Gender-Specific Fat Distribution and Association with Type 2 Diabetes Mellitus: A Study of Adiposity Indicators (DEXA, BMI, Waist-to-Hip Ratio) in Adults from Qatar.

Aim: This study aimed to investigate the difference in adiposity measured by DEXA between people with type 2 diabetes mellitus (T2DM) and those without. Moreover, we investigated the most reliable adiposity measure for discriminating people with T2DM from those without in clinical settings. Methods: A cross-sectional study was conducted from the database of Qatar Biobank (QBB), which comprised adults with a previous diagnosis of T2DM mellitus in Qatar. t-test and multivariable linear regression models were used to assess the association between T2DM and the difference in DEXA and BMI adiposity measures. Moreover, an evaluation of the odds of abnormal waist-hip ratio in participants with T2DM using an adjusted multivariable logistic regression was conducted. Results: Among the participants with T2DM, males had less fat in the leg region, while females had less fat in the legs and gynoid regions, compared to individuals without T2DM. Females with T2DM had a higher average BMI. Moreover, the odds of having an abnormal waist-to-hip ratio were higher in males and females with T2DM compared to persons without T2DM. Conclusion: There were different patterns of fat deposition in males and females with T2DM. T2DM was associated with a higher BMI in females only. The odds of abnormal waist-hip ratio were higher in individuals with T2DM of both genders. Waist-hip ratio showed reliable discrimination for T2DM and has implications for clinical practice.

Corrigendum to "Second round statewide sentinel-based population survey for estimation of the burden of active infection and anti-SARS-CoV-2 IgG antibodies in the general population of Karnataka, India, during January-February 2021" [IJID Regions Vol 1(2021) pages 107-116].

[This corrects the article DOI: 10.1016/j.ijregi.2021.10.008.].

Association of Subclinical Hypothyroidism with Type 2 Diabetes Mellitus in Qatar: A Cross-Sectional Study.

Purpose: The relationship between subclinical hypothyroidism and type 2 diabetes mellitus (T2DM) in Qatar is under-studied, despite the high prevalence of diabetes in the region. This study evaluates the potential association between subclinical hypothyroidism and T2DM in Qatar. Patients and Methods: A cross-sectional study used participants with and without T2DM from the Qatar Biobank (QBB). Logistic regression analysis was used to assess the association between subclinical hypothyroidism and T2DM, with multivariable logistic regression used to adjust for potential confounders. Results: The study found that subclinical hypothyroidism was significantly associated with a 2.82 increase in the odds of having T2DM (OR=2.82, 95% CI (1.13, 7.02), p=0.026) after adjusting for potential confounders. The proportion of subclinical hypothyroidism among individuals with T2DM in Qatar was 4.6%, significantly higher than in those without T2DM (2.8%, p=0.18). Conclusion: This study demonstrates a significant association between subclinical hypothyroidism and T2DM in Qatar. Further research is required to investigate the directionality of this association and its clinical implications.