Transverse coronary dissection resulting in abrupt vessel closure following directional coronary atherectomy: clinical, angiographic, and intracoronary ultrasound findings.

A 60-year-old man underwent directional coronary atherectomy (DCA) of the mid portion of a large, anatomically dominant left circumflex coronary artery, resulting in propagating transverse dissection and subsequent complete distal occlusion. Intravascular ultrasound imaging (IVUS) of the dissected segment demonstrated the entry point of the dissection, and systolic compression of the true vessel lumen, prior to angiographic deterioration of distal coronary flow.

The improvement and standardization of the simplified process for the production of foot and mouth disease virus from BHK suspension cells.

Improvements have been made to the methodology for the production of foot and mouth disease (FMD) virus from BHK 21 clone 13 suspension cells by the simplified process. Data derived from some 600 individual 8-1 cultures covering all seven types of FMD virus has been analysed. The production of virus was shown to (1) have no direct relationship to cell passage level and (2) to be inversely related to the cell multiplication factor observed during the cell growth cycle immediately prior to infection.