Urocytogram, an index of maturity in premature infants.

Cellular material found in urinary sediment stems essentially from exfoliated cells of the vesical triangle whose morphology is under the influence of the sex hormones. The study of cellular modifications forms the basis of a cytological procedure--the urocytogram. The urocytograms of 103 newborns, both premature and full term, made in the intensive care unit of the Department of Neonatal Medicine, Port-Royal Hospital, Paris, showed that marked changes in hormonal impregnation occur as a function of gestational age and permitted the establishment of a maturation index for the epithelium of the vesical triangle. In boys, the percentage of basal cells varied from 17.30 at 28 weeks' gestational age to 31.64 at term; while in girls the variation were less marked: 0.20 at 28 weeks to 1.37 at term. The oestrogen index (OI) was higher in a girl at 28 weeks (OI = 45.20) than in a girl born at term (OI = 13.50). The lower the gestational age the higher the pyknotic index (PI = 52.80 at 28 weeks), and the latter decreased as gestational age rose (PI = 23.12 at term). In boys, the oestrogen and pyknotic indices showed less variation (18.50 at 28 weeks and 15.29 at term). It thus appears that the urocytogram, a totally nontraumatic examination of urine samples obtained by simple miction, has its place among the tests of fetal maturity.

[Turner's syndrome and the urocytogram]. / Syndrome de Turner et urocytogrammes.

The cellular material studied in the urinary sediment mainly obtained from exfoliated cells of the bladder trigone was submitted to hormonal stimulation. These cell changes constitute the basis of a cytological method called urocytogram. The urinary sediment was examined in twenty seven girls with Turner's syndrome. The authors consider the interest of repeat examinations in the follow-up and treatment of these patients.

[Value of aspiration cytology for the evaluation of breast cancer recurrence]. / Intérêt de la ponction cytologique pour l'évaluation des recidives carcinomateuses du sein.

The authors studied at the "Centre Anticancéreux de Rennes" the value of fine needle aspiration cytology in the valuation of recurrences in breast cancers. The cytologic procedures were made on breast scars. The cytologic investigation interested 32 cases of carcinoma recurrences. The high rate of correct cytology diagnosis and the very low of wrong results prove the value and interest of the fine needle aspiration cytology for recurrences in breast cancers.

[Use of the urocytogram in sexual ambiguities before puberty]. / Applications de l'urocytogramme dans les ambiguités sexuelles avant la puberté.

The cellular material studied in the urinary sediment mainly obtained from exfoliated cells of the bladder trigone was submitted to hormonal stimulation. The urocytogram has proved a useful and even necessary examination to establish the hormonal check-up of a child suffering from early puberty. This simple, painless method, without any psychological consequences is also indicated in pediatric gynecology, and in certain sexual ambiguity cases. This examination, undergone by a child premature or not, contributes to the early diagnosis of congenital adrenal hyperplasia. In the course of childhood, it helps to investigate pseudohermaphroditisms and various malformations. This examination has proved an important help in the diagnosis of all the cases of sexual ambiguity.

[Applications of the urocytogram in primary-secondary amenorrhea in adolescents]. / Applications de l'urocytogramme dans les aménorrhées primo-secondaires chez les adolescentes.

In the urinary sediment, the cellular material mainly originates from cells of the bladdertrigone. These cells are submitted to hormonal stimulation and their study constitutes the base of a cytological method called "urocytogram". The urinary sediment was examined in thirty-five young girls with backward puberty. The repeated examinations contribute to differential diagnosis and help in etiologic diagnosis. Whenever it is necessary to investigate adolescent's sex hormones, an urocytogram, a simple and painless method, is indicated.

[Cellular material in urinary sediment in retarded or precocious puberty]. / Etude cellulaire du sédiment urinaire au cours des retards pubertaires et des pubertés précoces.

The cellular material studied in the urinary sediment mainly obtained from exfolied alls the bladder trigone was submitted to hormonal stimulation. These cell changes constitute the basis of a cytologic method called the urocytogram. The urocytogram was followed up in six children with early puberty and ten young girls with backward puberty. These repeated examinations contribute to the diagnosis and help in the differential diagnosis. Whenever it is necessary to investigate a child' sex hormones the urocytogram, simple painless method is indicated.