1.
Med Clin (Barc)
; 153(8): 338-339, 2019 10 25.
Artigo
em Inglês, Espanhol
| MEDLINE
| ID: mdl-30322651
Assuntos
Esclerose Tuberosa , Prestação Integrada de Cuidados de Saúde , Feminino , Marcadores Genéticos , Humanos , Masculino , Equipe de Assistência ao Paciente , Estudos Retrospectivos , Espanha , Centros de Atenção Terciária , Esclerose Tuberosa/diagnóstico , Esclerose Tuberosa/genética , Esclerose Tuberosa/terapia
2.
J Pediatr Hematol Oncol
; 40(2): e108-e110, 2018 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28859036
RESUMO
Hemophagocytic lymphohistiocytosis (HLH) is a condition caused by a pathologic immune activation, which is responsible for its signs and symptoms. It may also appear as a secondary process caused by malignancy. Developing HLH during treatment for acute lymphoblastic leukemia (ALL) is extremely uncommon, but underdiagnosis may be fatal. Two patients with ALL on chemotherapy maintenance treatment who developed HLH triggered by infection are presented here. We emphasize the importance of being aware of this condition when a patient with ALL in complete remission presents with unexplained hepatomegaly, cytopenia, and fever. Early diagnosis and treatment may be lifesaving.