Comparative in vitro evaluation of microgap in titanium stock versus cobalt-chrome custom abutments on a conical connection implant: Effect of crown cementation and ceramic veneering.

OBJECTIVE: To compare the implant-abutment connection microgap between computer-aided design and computer-aided manufacturing (CAD/CAM) milled or laser-sintered cobalt-chrome custom abutments with or without ceramic veneering and titanium stock abutments with or without crown cementation. MATERIAL AND METHODS: Six groups of six abutments each were prepared: (1) CAD/CAM cobalt-chrome custom abutments: milled, milled with ceramic veneering, laser-sintered, and laser-sintered with ceramic veneering (four groups: MIL, MIL-C, SIN, and SIN-C, respectively) and (2) titanium stock abutments with or without zirconia crown cementation (two groups: STK and STK-Z, respectively). Abutments were screwed to the implants by applying 30 Ncm torque. All 36 samples were sectioned along their long axes. The implant-abutment connection microgap was measured using scanning electron microscopy on the right and left sides of the connection at the upper, middle, and lower levels. Data were analyzed using the Kruskal-Wallis test (p < .05). RESULTS: Mean values (µm) of the microgap were 0.54 ± 0.44 (STK), 0.55 ± 0.48 (STK-Z), 1.53 ± 1.30 (MIL), 2.30 ± 2.2 (MIL-C), 1.53 ± 1.37 (SIN), and 1.87 ± 1.8 (SIN-C). Although significant differences were observed between the STK and STK-Z groups and the other groups (p < .05), none were observed between the milled and laser-sintered groups before or after ceramic veneering. The largest microgap was observed at the upper level in all groups. CONCLUSIONS: Titanium stock abutments provided a closer fit than cobalt-chrome custom abutments. Neither crown cementation nor ceramic veneering resulted in significant changes in the implant-abutment connection microgap.

Challenging Diagnosis of Invasive Sinus Aspergillosis Mimicking Gradenigo's Syndrome in an Elderly Patient with T-Cell Lymphoma.

(1) Background: Gradenigo's Syndrome (GS) is a rare complication of acute otitis media characterized by the triad of diplopia, otitis, and facial pain. The widespread use of antibiotics has significantly reduced its occurrence. (2) Case summary: We present the case of an elderly patient with T-cell lymphoma who developed neurological deficits resembling GS. The patient was ultimately diagnosed with invasive sinus aspergillosis. The diagnostic process was challenging due to the atypical clinical presentation and the lack of specific imaging findings. A biopsy was the most important test for clarifying the diagnosis. (3) Conclusions: The prognosis for this complication is extremely poor without surgery, and the patient died despite adequate antifungal coverage. Therefore, maintaining high clinical suspicion is paramount to avoid adverse outcomes in similar cases, particularly in the geriatric population, wherein this syndrome's occurrence may not be expected.

Garantías explícitas en salud odontológica de las embarazadas y la salud pública por regiones y años 2010-2019 en Chile

Objetivo: Estimar la tasa de uso de las Garantías Explícitas de Salud (GES) dental de la embarazada entre 2010 a 2019 en todas las regiones de Chile. Pacientes y métodos: Diseño: descriptivo, observacional. Participantes: mujeres embarazadas, atendidas en el sistema público. Se estudió un total de 1 854 621 gestantes, 1 445 903 de gestantes con ingreso al GES y 1 257 775 de gestantes con alta dental integral pertenecientes a cada región y año analizado. Mediciones: estimación de tasas de uso del GES odontológico, análisis de las tasas de eficacia y de la evolución de las tasas de uso del GES mediante series de tiempo. Resultados: Las medias del uso del GES y la eficacia de la atención por GES fue inferior al valor óptimo (100 %). Ambas tasas difieren del valor meta de la autoridad sanitaria. Los valores de las tasas del uso del GES varían por año y región. La forma de las curvas fue predominantemente no lineal. Conclusión: El uso y la eficacia del GES odontológico en embarazadas chilenas no está en correspondencia con los objetivos del Ministerio de Salud Pública. Se requieren nuevos estudios para explicar las causas de estos resultados.

Objective. Estimate the rate of use of the Explicit Dental Health Guarantees (GES) by pregnant women from 2010 to 2019 in the regions of Chile. Patients and methods. Design: Descriptive, observational. Participants: Pregnant women, cared for in the public system. The total of pregnant women (1,854,621), pregnant women admitted to the GES (1,445,903), and pregnant women with full dental discharge (1,257,775) belonging to each of the regions and years analyzed (2010-2019) were studied. Measurements: estimation of dental GES use rates, evolution of rates over time using time series (regressions). Results. The means of the use of the GES and the effectiveness of the care by the GES was less than the optimal value (100%). Both rates differ from the target value of the health authority. The value of usage fees varies by year and region. The shape of the curves was predominantly non-linear. Conclusions. The use and effectiveness of the dental GES in Chilean pregnant women is not in correspondence with the objectives of the Ministry of Public Health. New studies are required to explain the causes of these results.

Orthopedic Surgeons' Accuracy When Orienting an Acetabular Cup. A Comparison with Untrained Individuals.

Background and Objectives: Previous studies demonstrated a huge variability among surgeons when it comes to reproducing the position of an acetabular cup in total hip arthroplasty. Our main objective is to determine if orthopedic surgeons can replicate a given orientation on a pelvic model better than untrained individuals. Our secondary objective is to determine if experience has any influence on their ability for this task. Materials and Methods: A group of specialist orthopedic hip surgeons and a group of volunteers with no medical training were asked to reproduce three given (randomly generated) acetabular cup orientations (inclination and anteversion) on a pelvic model. Error was measured by means of a hip navigation system and comparisons between groups were made using the appropriate statistical methods. Results: The study included 107 individuals, 36 orthopedic surgeons and 71 untrained volunteers. The mean error among surgeons was slightly greater as regards both inclination (7.84 ± 5.53 vs. 6.70 ± 4.03) and anteversion (5.85 ± 4.52 vs. 5.48 ± 3.44), although statistical significance was not reached (p = 0.226 and p = 0.639, respectively). Similarly, although surgeons with more than 100 procedures a year obtained better results than those with less surgical experience (8.01 vs. 7.67 degrees of error in inclination and 5.83 vs. 5.87 in anteversion), this difference was not statistically significant, either (p = 0.852 and p = 0.981). Conclusions: No differences were found in the average error made by orthopedic surgeons and untrained individuals. Furthermore, the surgeons' cup orientation accuracy was not seen to improve significantly with experience.

Trends in HIV Infection Incidence in a Mostly Mining Population

Objective: To determine the trends in the incidence of HIV infection in the Atacama region, Chile, according to age and sex, for the 2010-2017 period. Material and Methods: Analysis from the database of confirmed HIV-positive diagnosis cases. HIV incidence rates were made up from confirmed HIV cases adjusted by year, age, and sex, with population denominators from the INE. General and specific trend analysis was performed using regression equations. Results: The groups with the highest incidence of HIV infection were: 20-29 years, 30-39 years, and 40-49 years. The analysis of the curve and its general trend showed that the growth curve of the 20-29 years group is the strongest. Adjusting for sex, it was observed that, in men, the 20-29 years group has the strongest growth and growth forecast of all groups, followed by men aged 50-59 years. In the case of women, the 50-59 and 60-69 age groups are the fastest growing, however, it is a slower growth in relation to the men's group. Conclusions: Chile has one of the fastest growing HIV epidemics in the world. We estimate that the most incidental groups are linked to the mining population, which denotes the importance of the relationship between mining activity and the high incidence of HIV infection. The results suggest the need for prevention and early detection of the sources of HIV infection and the need to adapt strategies in this population. It is necessary to close the gap of HIV-positive people who do not know their health status, in order to stop the spread of HIV among miners and in the communities surrounding the mining industry.

Objetivo: Determinar las tendencias de la incidencia del contagio por VIH en la región de Atacama, Chile, según edad y sexo, para el período 2010-2017. Materiales y Métodos: Análisis desde la base de datos de casos confirmados de diagnóstico de VIH positivos. Las tasas de incidencia de VIH se confeccionaron a partir de los casos confirmados por VIH ajustados por año, edad y sexo, con denominadores poblacionales del INE. Se realizó un análisis de tendencia general y específica mediante ecuaciones de regresión. Resultados: Los grupos con mayor incidencia de infección por VIH fueron: 20-29 años, 3039 años y 40-49 años. El análisis de la curva y su tendencia general mostró que la curva de crecimiento del grupo 20-29 años es la más fuerte. Ajustando por sexo, se observó que en los hombres del grupo 20-29 años el crecimiento y el pronóstico de crecimiento es el más fuerte de todos los grupos, seguido por hombres de 50-59 años. En el caso de las mujeres, los grupos más incidentes fueron 50-59 y 60-69 años. Conclusiones: Chile tiene una de las epidemias de VIH de más rápido crecimiento en el mundo. Estimamos que los grupos más incidentes están vinculados a la población minera, lo que denota la importancia de la relación existente entre la actividad minera y la alta incidencia del contagio por VIH. Los resultados sugieren la necesidad de prevenir y pesquisar tempranamente las fuentes de infección por VIH y adaptar las estrategias en esta población.

Relación entre la tasa de letalidad por COVID-19 y los recursos hospitalarios / Relation between COVID-19 fatality rate and hospital resources

Introducción: La tasa de letalidad por COVID-19 ha generado mucha preocupación entre los ciudadanos y los medios de comunicación con respecto a los números oficiales proporcionados por distintos gobiernos. La salud pública en la actualidad debe hacer frente a la pandemia más significativa del siglo xxi. Objetivo: Analizar la tasa de letalidad por COVID-19 y su relación con recursos hospitalarios críticos, en el contexto de la pandemia de la COVID-19. Métodos: Se analizó la tasa de letalidad sobre la base de datos oficiales. Se subestimó el número de casos para obtener una estimación más real del alcance de la infección, de los indicadores de recursos hospitalarios importantes (críticos) en transición pandémica que podrían elevar la tasa de letalidad posterior al estudio. Se emplearon curvas de tendencia exponencial doblemente suavizadas, distribución S y técnicas de regresión. Resultados: La curva que mejor explicó el comportamiento de fallecidos por COVID-19 en Chile fue una ecuación de regresión cúbica. La variable hospitalización básica se distribuyó como una curva S. Las variables hospitalización media, pacientes críticos, unidad tratamiento intensivo, unidad cuidado intensivo, ventiladores mecánicos totales y ventiladores mecánicos ocupados; se pudieron explicar mediante regresiones cúbicas. En todos los casos, los valores de R2 fueron superiores al 95 por ciento. Conclusiones: El número de fallecidos seguirá en aumento. Se sugiere fortificar las unidades de hospitalización básica para imposibilitar el colapso de la red sanitaria. Es necesario seguir creciendo en términos de hospitalización de media complejidad, unidad tratamiento intensivo, unidad cuidado intensivo y número total de ventiladores mecánicos para asegurar el soporte sanitario(AU)

Introduction: The fatality rate by COVID-19 has generated a lot of concern among citizens and the media regarding the official numbers provided by different governments. Public health today must cope with the most significant pandemic of the twenty-first century. Objective: Analyze the fatality rate due to COVID-19 and its relation with critical hospital resources, in the context of the COVID-19 pandemic. Methods: The fatality rate was analyzed on the basis of official data. The number of cases was underestimated to obtain a more real estimate of the extent of the infection, of the indicators of important (critical) hospital resources in pandemic transition that could raise the post-study fatality rate. Double-smoothed exponential trend curves, S-distribution and regression techniques were used. Results: The curve that best explained the behavior of COVID-19 deaths in Chile was a cubic regression equation. The basic hospitalization variable was distributed as an S-curve. The variables called mean hospitalization, critical patients, intensive treatment unit, intensive care unit, total mechanical ventilators and busy mechanical ventilators could be explained by cubic regressions. In all cases, R2 values were greater than 95percent. Conclusions: The number of deaths will continue to rise. It is suggested to fortify the basic hospitalization units to prevent the collapse of the health network. It is necessary to continue growing in terms of medium complexity hospitalization, intensive treatment unit, intensive care unit and total number of mechanical ventilators to ensure health support(AU)

[Prediction of end of lockdown post-peak of cases in first wave of the COVID-19 pandemic in Chile]. / Predicción del fin del confinamiento después del máximo de casos en la primera ola de la pandemia COVID-19 en Chile.

INTRODUCTION: The results of mandatory confinement have been detrimental in several respects. Nonetheless, they have resulted in reducing the number of active cases of COVID-19. Chile has begun the de-escalation and needs to know the best time to end the restrictions. OBJECTIVE: We discuss the best conditions and guarantees for the end of compulsory confinement. METHODS: This study is based on a trend model with prediction estimation. The data of the variables of interest were subjected to linear regression studies to determine the curve that best explained the data. The coefficient of determination, the standard deviation of y in x, and the confidence interval of the observed curve were estimated. The trend curve was chosen in accordance with the regression estimates. OUTCOMES: It was found that all dependent variables tended to decrease over time in a quadratic fashion, except for the new cases variable. In general, the R2 and MAPE estimates are satisfactory, except for the variable number of PCR tests per day. CONCLUSIONS: Gradual and cautious steps should be taken before ending mandatory confinement. In the current de-escalator, daily PCR tests should be increased, maintaining vigilance on indicators of incidence, prevalence, and positivity of PCR tests. Evidence suggests with some degree of confidence that mandatory confinement could be safely lifted as of August 30, 2020. Long-term preparations must be made to contain future waves of new cases.

INTRODUCCIÓN: Los resultados del confinamiento obligatorio han sido perjudiciales en varios aspectos. No obstante, han surtido efecto en lograr el descenso de casos activos de COVID-19. Chile ha comenzado la desescalada y precisa conocer el mejor momento para poner fin a las restricciones. OBJETIVOS: Discutir las mejores condiciones y garantías para el fin del confinamiento obligatorio sobre la base de los casos nuevos, casos activos y positividad de exámenes de reacción en cadena de la polimerasa. MÉTODOS: Estudio basado en un modelo de tendencia con estimación de predicciones. Los datos de las variables de interés fueron sometidas a estudios de regresión lineal, con el objeto de determinar la curva que mejor explicaba los datos. Se estimó el coeficiente de determinación, la desviación estándar de y en x y el intervalo de confianza de la curva observada. Posteriormente, fue escogida la curva de tendencia en concordancia con las estimaciones de regresión. RESULTADOS: Se encontró que todas las variables dependientes tendían a disminuir con el tiempo de forma cuadrática, con excepción de la variable casos nuevos. En general, las estimaciones de coeficiente de determinación (R2) y error porcentual absoluto medio son satisfactorias, con excepción de la variable: número de exámenes de reacción en cadena de la polimerasa por día. CONCLUSIONES: Se deben tomar medidas graduales y cautelosas antes de poner fin al confinamiento obligatorio. En la actual desescalada, se deben aumentar los exámenes de reacción en cadena de la polimerasa diarios y mantener vigilancia en los indicadores de incidencia, prevalencia y positividad de dichos exámenes. La evidencia sugiere con cierto grado de confiabilidad que el confinamiento obligatorio podría levantarse de forma segura a contar del día 30 de agosto de 2020. Se deben hacer preparativos a largo plazo en contención de las futuras olas, es decir, una nueva alza de casos nuevos y activos luego del descenso.

Predicción del fin del confinamiento después del máximo de casos en la primera ola de la pandemia COVID-19 en Chile / Prediction of end of lockdown post-peak of cases in first wave of the COVID-19 pandemic in Chile

Introducción Los resultados del confinamiento obligatorio han sido perjudiciales en varios aspectos. No obstante, han surtido efecto en lograr el descenso de casos activos de COVID-19. Chile ha comenzado la desescalada y precisa conocer el mejor momento para poner fin a las restricciones. Objetivos Discutir las mejores condiciones y garantías para el fin del confinamiento obligatorio sobre la base de los casos nuevos, casos activos y positividad de exámenes de reacción en cadena de la polimerasa. Métodos Estudio basado en un modelo de tendencia con estimación de predicciones. Los datos de las variables de interés fueron sometidas a estudios de regresión lineal, con el objeto de determinar la curva que mejor explicaba los datos. Se estimó el coeficiente de determinación, la desviación estándar de y en x y el intervalo de confianza de la curva observada. Posteriormente, fue escogida la curva de tendencia en concordancia con las estimaciones de regresión. Resultados Se encontró que todas las variables dependientes tendían a disminuir con el tiempo de forma cuadrática, con excepción de la variable casos nuevos. En general, las estimaciones de coeficiente de determinación (R2) y error porcentual absoluto medio son satisfactorias, con excepción de la variable: número de exámenes de reacción en cadena de la polimerasa por día. Conclusiones Se deben tomar medidas graduales y cautelosas antes de poner fin al confinamiento obligatorio. En la actual desescalada, se deben aumentar los exámenes de reacción en cadena de la polimerasa diarios y mantener vigilancia en los indicadores de incidencia, prevalencia y positividad de dichos exámenes. La evidencia sugiere con cierto grado de confiabilidad que el confinamiento obligatorio podría levantarse de forma segura a contar del día 30 de agosto de 2020. Se deben hacer preparativos a largo plazo en contención de las futuras olas, es decir, una nueva alza de casos nuevos y activos luego del descenso.

Introduction The results of mandatory confinement have been detrimental in several respects. Nonetheless, they have resulted in reducing the number of active cases of COVID-19. Chile has begun the de-escalation and needs to know the best time to end the restrictions. Objective We discuss the best conditions and guarantees for the end of compulsory confinement. Methods This study is based on a trend model with prediction estimation. The data of the variables of interest were subjected to linear regression studies to determine the curve that best explained the data. The coefficient of determination, the standard deviation of y in x, and the confidence interval of the observed curve were estimated. The trend curve was chosen in accordance with the regression estimates. Outcomes It was found that all dependent variables tended to decrease over time in a quadratic fashion, except for the new cases variable. In general, the R2 and MAPE estimates are satisfactory, except for the variable number of PCR tests per day. Conclusions Gradual and cautious steps should be taken before ending mandatory confinement. In the current de-escalator, daily PCR tests should be increased, maintaining vigilance on indicators of incidence, prevalence, and positivity of PCR tests. Evidence suggests with some degree of confidence that mandatory confinement could be safely lifted as of August 30, 2020. Long-term preparations must be made to contain future waves of new cases.

Which curve provides the best explanation of the growth in confirmed COVID-19 cases in Chile?

OBJECTIVE: to explore the best type of curve or trend model that could explain the epidemiological behavior of the infection by COVID-19 and derive the possible causes that contribute to explain the corresponding model and the health implications that can be inferred. METHOD: data were collected from the COVID-19 reports of the Department of Epidemiology, Ministry of Health, Chile. Curve adjustment studies were developed with the data in four different models: quadratic, exponential, simple exponential smoothing, and double exponential smoothing. The significance level used was α≤0.05. RESULTS: the curve that best fits the evolution of the accumulated confirmed cases of COVID-19 in Chile is the doubly-smoothed exponential curve. CONCLUSION: the number of infected patients will continue to increase. Chile needs to remain vigilant and adjust the strategies around the prevention and control measures. The behavior of the population plays a fundamental role. We suggest not relaxing restrictions and further improving epidemiological surveillance. Emergency preparations are needed and more resource elements need to be added to the current health support. This prediction is provisional and depends on keeping all intervening variables constant. Any alteration will modify the prediction.

Which curve provides the best explanation of the growth in confirmed COVID-19 cases in Chile? / Qual é a curva que melhor explica o crescimento de casos confirmados da COVID-19 no Chile? / ¿Cuál es la curva que mejor explica el crecimiento de los casos confirmados de COVID-19 en Chile?

Objective to explore the best type of curve or trend model that could explain the epidemiological behavior of the infection by COVID-19 and derive the possible causes that contribute to explain the corresponding model and the health implications that can be inferred. Method data were collected from the COVID-19 reports of the Department of Epidemiology, Ministry of Health, Chile. Curve adjustment studies were developed with the data in four different models: quadratic, exponential, simple exponential smoothing, and double exponential smoothing. The significance level used was α≤0.05. Results the curve that best fits the evolution of the accumulated confirmed cases of COVID-19 in Chile is the doubly-smoothed exponential curve. Conclusion the number of infected patients will continue to increase. Chile needs to remain vigilant and adjust the strategies around the prevention and control measures. The behavior of the population plays a fundamental role. We suggest not relaxing restrictions and further improving epidemiological surveillance. Emergency preparations are needed and more resource elements need to be added to the current health support. This prediction is provisional and depends on keeping all intervening variables constant. Any alteration will modify the prediction.

Tendencias de la incidencia del virus de la inmunodeficiencia humana (VIH) en Chile, según edad y género 2010-2017 / Trends in the incidence of the human immunodeficiency (HIV) virus in Chile, by age and gender 2010-2017

RESUMEN Objetivos Determinar las tendencias de la incidencia del contagio por VIH en Chile, según edad y género, para el período 2010-2017. Métodos Análisis desde la base de datos de casos confirmados de diagnóstico de VIH positivos. Las tasas de incidencia de VIH se confeccionaron a partir de los casos confirmados por VIH ajustados por año, edad y sexo, con denominadores poblacionales del INE. Se realizó un análisis de tendencia general y específica mediante ecuaciones de regresión. Resultados Existe tendencia al aumento en tasas de incidencia del VIH en el periodo de estudio. El 36,48% de los casos reportados corresponde al sexo masculino entre 20 y 29 años, grupo con más alta incidencia en el período. Las ecuaciones de regresión estimadas efectivamente aumentan más sostenidamente en población masculina y joven. Conclusiones Existen factores informativos y educacionales deficitarios en la prevención del VIH en la población chilena. A pesar de la fuerte progresión de los casos nuevos, aún resta consolidar la brecha diagnóstica de personas que viven con VIH que desconocen su estado de salud. Se identificaron brechas entre recomendaciones, políticas públicas y resultados chilenos obtenidos.(AU)

ABSTRACT Objetive To determine the trends in the incidence of contagion by the HIV in Chile, according to age and gender, for the period 2010-2017. Methods Analysis from the database of confirmed HIV positive diagnosis cases. HIV incidence rates were made from HIV-confirmed cases adjusted for year, age, and sex, with population denominators from the INE. A general and specific trend analysis was performed using regression equations. Results There is a trend to increase in HIV incidence rates in the study period. 36.48% of the reported cases correspond to the male sex between 20-29 years, group with the highest incidence in the period. The estimated regression equations effectively increase more steadily in the male and young population. Conclusions There are deficit informative and educational factors in HIV prevention in the Chilean population. Despite the strong progression of new cases, the diagnostic gap of people living with HIV who are unaware of their health remains to be consolidated. Gaps were identified between recommendations, public policies and the Chilean results obtained.(AU)

Causas de mortinatalidad en Chile entre 2002-2015 / Causes of stillbirth in Chile from 2002 to 2015

RESUMEN Introducción: Un mortinato, es un evento del embarazo que supone un resultado negativo para padres, familias y personal de salud involucrado. La falta de recursos podría ser el principal obstáculo al acceso de atención prenatal, síntoma de inequidades en salud. El débil conocimiento de causas de mortinatalidad se asocia a la creencia de que son inevitables; sin embargo, muchos factores vinculantes son potencialmente modificables. Objetivo: Describir las causas de mortinatalidad en Chile. Material y métodos: Estudio transversal y analítico. El análisis se precisó desde las 22 semanas gestacionales, según criterio estándar de la Organización Mundial de la Salud. Las causas de mayor frecuencia se utilizaron para determinar asociación mediante test con nivel de significación estadística p<0,05. Resultados: El mayor porcentaje de muertes fetales se registró a las 35 o más semanas (35,63%). Principales macro-causas de mortinatalidad fueron tipo: fetal (47,0%), placentaria (31,4%) y desconocida (10,89%). Principales causas específicas fueron: hipoxia intrauterina (24,4%), causa no especificada (10,87%), y anomalías morfológicas-funcionales placentarias (10,83%). Causa específica hipoxia intrauterina se asocia a edad gestacional, edad materna y nivel educacional materno (p<0,05). Conclusiones: La salud prenatal es reflejo de atención obstétrica, calidad y progreso en atención sanitaria. Existen brechas en detección de causas y calidad de los registros, por lo que las causas desconocidas tiendan al alza en el tiempo. Es recomendable adicionar al registro de muertes fetales componentes temporal, biológico y social maternos.

ABSTRACT Introduction: A stillbirth is an event in pregnancy that supposes a negative result for parents, families and the health personnel involved. The lack of resources could be the main obstacle to accessing prenatal care, a symptom of health imbalance. The poor knowledge of the causes of stillbirth is associated with the belief that these events are inevitable; however, many binding factors are potentially modifiable. Objective: To describe the causes of stillbirths in Chile. Material and methods: A cross-sectional and analytical study was conducted. The analysis was determined from the 22 weeks´ gestation, according to the standard criterion of the World Health Organization. The most frequent causes were used to determine the association between test and the level of statistical significance p <0.05. Results: The highest percentage of fetal deaths was recorded at 35 or more weeks (35.63%). The main macro-causes of stillbirth were: fetal (47.0%), placental (31.4%), and unknown (10.89%). The main specific causes were intrauterine hypoxia (24.4%), unspecified cause (10.87%), and placental morphological-functional abnormalities (10.83%). The specific cause of intrauterine hypoxia is associated with gestational age, maternal age, and maternal educational level (p <0.05). Conclusions: Prenatal health demonstrates obstetric care, quality, and progress in health care. There are gaps in the detection of the causes and quality of records, so unknown causes tend to rise over time. It is advisable to add temporal, biological and social components to the registry of fetal deaths.

[Trends in the incidence of the human immunodeficiency (HIV) virus in Chile, by age and gender 2010-2017]. / Tendencias de la incidencia del virus de la inmunodeficiencia humana (VIH) en Chile, según edad y género 2010-2017.

OBJETIVE: To determine the trends in the incidence of contagion by the HIV in Chile, according to age and gender, for the period 2010-2017. METHODS: Analysis from the database of confirmed HIV positive diagnosis cases. HIV incidence rates were made from HIV-confirmed cases adjusted for year, age, and sex, with population denominators from the INE. A general and specific trend analysis was performed using regression equations. RESULTS: There is a trend to increase in HIV incidence rates in the study period. 36.48% of the reported cases correspond to the male sex between 20-29 years, group with the highest incidence in the period. The estimated regression equations effectively increase more steadily in the male and young population. CONCLUSIONS: There are deficit informative and educational factors in HIV prevention in the Chilean population. Despite the strong progression of new cases, the diagnostic gap of people living with HIV who are unaware of their health remains to be consolidated. Gaps were identified between recommendations, public policies and the Chilean results obtained.

OBJETIVOS: Determinar las tendencias de la incidencia del contagio por VIH en Chile, según edad y género, para el período 2010-2017. MÉTODOS: Análisis desde la base de datos de casos confirmados de diagnóstico de VIH positivos. Las tasas de incidencia de VIH se confeccionaron a partir de los casos confirmados por VIH ajustados por año, edad y sexo, con denominadores poblacionales del INE. Se realizó un análisis de tendencia general y específica mediante ecuaciones de regresión. RESULTADOS: Existe tendencia al aumento en tasas de incidencia del VIH en el periodo de estudio. El 36,48% de los casos reportados corresponde al sexo masculino entre 20 y 29 años, grupo con más alta incidencia en el período. Las ecuaciones de regresión estimadas efectivamente aumentan más sostenidamente en población masculina y joven. CONCLUSIONES: Existen factores informativos y educacionales deficitarios en la prevención del VIH en la población chilena. A pesar de la fuerte progresión de los casos nuevos, aún resta consolidar la brecha diagnóstica de personas que viven con VIH que desconocen su estado de salud. Se identificaron brechas entre recomendaciones, políticas públicas y resultados chilenos obtenidos.