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Diagn Microbiol Infect Dis ; 103(4): 115729, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35716422

RESUMO

BACKGROUND: Skin and soft tissue infections (SSTIs) are commonly caused by group A Streptococcus (GAS). Rapid molecular assays for detecting GAS in wounds would help with clinical management. This study assessed a point-of-care system for the detection of GAS in non-severe SSTIs in a Native American community in the Southwest. METHODS: Patients presenting with a new non-severe SSTI were eligible if a swab was collected. The swab was tested by traditional culture methods and using the cobas® Liat® point-of-care (POC) system and results were compared. RESULTS: 399 samples were included. The final result from the POC assay was positive for 52.0% of samples. Compared to culture, the POC assay had a sensitivity of 100% and specificity of 99.5%. CONCLUSIONS: The cobas® Liat® system accurately and efficiently identified GAS in non-severe SSTIs. Having a POC test available to rapidly identify or rule out GAS could help to minimize overuse of antibiotics.


Assuntos
Infecções dos Tecidos Moles , Humanos , Patologia Molecular , Sistemas Automatizados de Assistência Junto ao Leito , Sensibilidade e Especificidade , Infecções dos Tecidos Moles/diagnóstico , Streptococcus pyogenes/genética
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