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1.
Eur Rev Med Pharmacol Sci ; 26(23): 8637-8643, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-36524483

RESUMO

This paper is dedicated to reviewing relative research on humanistic caring ability of intern nursing students and proposing strategies to improve humanistic caring ability. Firstly, current paper collected information from both domestic and foreign literature, and then scientific analysis, summary and overview of research results were conducted with regards to humanistic caring ability of interns nursing students. By analyzing the current situation of intern nursing students' humanistic caring ability, and factors that have influence on humanistic caring ability of intern nursing students, the present paper is determined to come up with feasible change methods and form strategic paths. At present, the humanistic care ability of intern nursing students is relatively low. Students, schools, hospitals, and the society all exert influence on the humanistic care ability of intern nursing students. Although scholars' research is different in topics or focus, the conclusions drawn from this research are highly consistent. Nursing humanistic care is the internal quality of nursing staff concerning morality, humanity, and integration of knowledge, concepts, and attitudes. Nursing humanistic care ability includes caring experience ability and caring behavior ability. The necessary psychological characteristics of personality are regarded as a special ability. It is of great significance to promote the quality of nursing and humanistic care ability of intern nursing students who serve as the backup force of nursing talent team. Meanwhile, it is imperative to strengthen the construction of intern nursing students' humanistic care ability.


Assuntos
Estudantes de Enfermagem , Humanos , Estudantes de Enfermagem/psicologia , Humanismo
2.
Fish Shellfish Immunol ; 52: 85-93, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26993612

RESUMO

Inhibitors of nuclear factor kappa B (IκBs) are major control components of the Rel/NF-κB signaling pathway, a key regulator in the modulation of the expression of immune-related genes in vertebrates and invertebrates. The activation of the Rel/NF-κB signaling pathway depends largely in the degradation of IκB proteins and thus, IκBs are a main target for the identification of genes whose expression is controlled by Rel/NF-κB pathway. In order to identify such regulation in bivalve mollusks, the cDNA sequence encoding an IκB protein was characterized in the scallop Argopecten purpuratus, ApIκB. The cDNA sequence of ApIκB is comprised of 1480 nucleotides with a 1086 bp open reading frame encoding for 362 amino acids. Bioinformatics analysis showed that ApIκB displays the conserved features of IκB proteins. The deduced amino acid sequence consists of a 39.7 kDa protein, which has an N-terminal degradation motif, six ankyrin repeats and a C-terminal phosphorylation site motif. Phylogenetic analysis revealed a high degree of identity between ApIκB and other IκBs from mollusks, but also to arthropod cactus proteins and vertebrate IκBs. Tissue expression analysis indicated that ApIκB is expressed in all examined tissues and it is upregulated in circulating hemocytes from scallops challenged with the pathogenic Gram-negative bacterium Vibrio splendidus. After inhibiting ApIκB gene expression using the RNA interference technology, the gene expression of the antimicrobial peptide big defensin was upregulated in hemocytes from non-challenged scallops. Results suggest that ApIκB may control the expression of antimicrobial effectors such as big defensin via a putative Rel/NF-κB signaling pathway. This first evidence will help to deepen the knowledge of the Rel/NF-κB conserved pathway in scallops.


Assuntos
Peptídeos Catiônicos Antimicrobianos/metabolismo , Expressão Gênica , NF-kappa B/antagonistas & inibidores , Pectinidae/genética , Pectinidae/imunologia , Sequência de Aminoácidos , Animais , Peptídeos Catiônicos Antimicrobianos/genética , Clonagem Molecular , DNA Complementar/genética , DNA Complementar/metabolismo , Proteínas I-kappa B/química , Proteínas I-kappa B/genética , Proteínas I-kappa B/metabolismo , NF-kappa B/genética , NF-kappa B/metabolismo , Especificidade de Órgãos , Moléculas com Motivos Associados a Patógenos/farmacologia , Pectinidae/metabolismo , Filogenia , RNA Mensageiro/genética , RNA Mensageiro/metabolismo , Alinhamento de Sequência , Homologia Estrutural de Proteína
3.
Appl Opt ; 33(7): 1194-7, 1994 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-20862137

RESUMO

We implement a digital fringe-counting technique to measure in real time the relative mirror displacement of a suspended Michelson interferometer with modulated optical path length for oscillations much larger than the laser wavelength (λ). This provides the proper error signal for a servo mechanism that reduces the relative displacement within λ/2. The implemented technique does not require extra optics or polarizers and thus can be used for interferometric gravitational wave detectors as a starting procedure to get the system locked.

4.
Appl Opt ; 33(34): 7846-56, 1994 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-20962998

RESUMO

We discuss the application of digital systems to the automatic control of dual-wave optical interferometers. We show that, if the mechanical-modulation technique is used for error-signal extraction, digital techniques can be used both for error-signal extraction and for control-signal generation. Therefore, apart from two front/end amplifiers that are necessary to match the dynamics of the detectors and actuators to the dynamics of the analog-to-digital converters and digital-to-analog converters, no other analog devices are required. In particular, the mechanical-modulation technique requires the synchronous demodulation of the photodiode output signal. Hence we need to implement a digital lock-in amplifier whose algorithm is described here. Finally, we describe one of the possible applications of this digital control procedure, such as the control of a classic Mach-Zehnder interferometer in air.

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