RESUMO
BACKGROUND: Australia has the highest incidence of skin cancer globally. Early detection and treatment of skin cancer is critical for positive patient outcomes. General practitioners (GPs) play a central role in skin cancer management in Australia. OBJECTIVE: Collaboration between GPs and pathologists can improve the accuracy of skin cancer diagnosis. However, for improvement to occur, clear communication and high-quality specimens are essential. DISCUSSION: Inadequate clinical information and suboptimal biopsy specimens can hinder diagnosis. Improved communication, targeted training and selecting appropriate biopsy techniques are essential. A collaborative approach, guided by recommended techniques and clear guidelines, can minimise errors and improve patient outcomes in Australia's GP-led skin cancer management system.
Assuntos
Patologistas , Neoplasias Cutâneas , Humanos , Neoplasias Cutâneas/terapia , Neoplasias Cutâneas/diagnóstico , Austrália , Biópsia/métodos , Clínicos GeraisAssuntos
Dermoscopia/métodos , Melanoma/patologia , Recidiva Local de Neoplasia/diagnóstico , Fotografação/métodos , Neoplasias Cutâneas/patologia , Detecção Precoce de Câncer , Seguimentos , Humanos , Masculino , Melanoma/terapia , Pessoa de Meia-Idade , Monitorização Fisiológica/métodos , Recidiva Local de Neoplasia/terapia , Neoplasias Cutâneas/terapiaRESUMO
The term "dysplastic nevus" (DN) implies that this nevus exists as a distinct and defined entity of potential detriment to its host. We examine the current data, which suggest that this entity exists as histologically and possibly genetically different from common nevus, with some overlapping features. Studies show that a melanoma associated with a nevus is just as likely to arise in a common nevus as in DN. Furthermore, there is no evidence that a histologically defined DN evolves into a melanoma or that the presence of 1 or more DN on an individual patient confers any increased melanoma risk. We suggest that the term "dysplastic nevus" be abandoned so that the focus can shift to confirmed and relevant indicators of melanoma risk, including high nevus counts and large nevus size.
Assuntos
Síndrome do Nevo Displásico/patologia , Melanoma/patologia , Nevo Pigmentado/patologia , Lesões Pré-Cancerosas/patologia , Neoplasias Cutâneas/patologia , Biópsia por Agulha , Transformação Celular Neoplásica , Diagnóstico Diferencial , Síndrome do Nevo Displásico/diagnóstico , Feminino , Humanos , Imuno-Histoquímica , Masculino , Melanoma/diagnóstico , Nevo Pigmentado/diagnóstico , Sensibilidade e Especificidade , Neoplasias Cutâneas/diagnósticoRESUMO
Acquired Perforating Dermatosis (APD) is a perforating disease characterized by transepidermal elimination of dermal material [1,2]. This disease usually develops in adulthood. APD has been reported to occur in association with various diseases, but is most commonly associated with dialysis-dependent chronic renal failure (CRF) or diabetes mellitus (DM) [1,2,3,4]. Morton et al found that APD occurs in up to 10% of patients undergoing hemodialysis [5]. Additionally, Saray et al found that sixteen of twenty-two cases with APD were associated with CRF [3].