RESUMO
This phase I/II study evaluates the influence of selected vegetables (SV) that contain known antitumor components on the survival of stage III-IV non-small cell lung cancer (NSCLC) patients. All patients were treated with conventional therapies. SV was added to the daily diet of 5 stage I patients in the toxicity study group (TG) and 6 stage III and IV patients in the treatment group (SVG), but not to the diet of 13 stage III and IV patients in the control group (CG). Age, Karnofsky performance status (KPS), and body mass index of SVG and CG patients were comparable at entry. KPS declined in the CG patients (79 +/- 8 to 55 +/- 11) but improved in the SVG patients (75 +/- 8 to 80 +/- 13) one to three months after entry. Weight change in the CG, SVG, and TG patients was -12 +/- 5%, -2 +/- 2%, and +4 +/- 4%, respectively. The median survival time and mean survival of the CG patients were 4 and 4.8 months, but in the SVG patients they were 15.5 and 15 months (p < 0.01). No clinical signs of toxicity were found in the TG patients in the 24-month study period. Adding SV to the daily diet of NSCLC patients was found to be nontoxic and associated with improved weight maintenance, KPS, and survival of stage III and IV NSCLC patients.
Assuntos
Carcinoma Pulmonar de Células não Pequenas/dietoterapia , Suplementos Nutricionais , Neoplasias Pulmonares/dietoterapia , Magnoliopsida , Verduras , Adulto , Idoso , Índice de Massa Corporal , Carcinoma Pulmonar de Células não Pequenas/mortalidade , República Tcheca/epidemiologia , Feminino , Humanos , Avaliação de Estado de Karnofsky , Neoplasias Pulmonares/mortalidade , Masculino , Pessoa de Meia-Idade , Análise de SobrevidaAssuntos
Adenocarcinoma Papilar/secundário , Neoplasias da Coluna Vertebral/secundário , Neoplasias da Glândula Tireoide/diagnóstico por imagem , Adenocarcinoma Papilar/diagnóstico por imagem , Feminino , Humanos , Pessoa de Meia-Idade , Radiografia , Cintilografia , Neoplasias da Coluna Vertebral/diagnóstico por imagemAssuntos
Hipotireoidismo/sangue , Lipídeos/sangue , Adulto , Idoso , Colesterol/sangue , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Hormônios Tireóideos/sangueAssuntos
Vértebras Lombares , Osteomielite/diagnóstico , Idoso , Diagnóstico Diferencial , Feminino , Humanos , Osteomielite/terapiaRESUMO
Scintigraphic scanning of the lumbar spine skeleton was performed in 9 patients with spondylodiscitis following an operation for the herniation of a lumbar intervertebral disk. The difference in scintigraphic findings demonstrates the valuable diagnostic contribution of this examination to an early diagnosis of postoperative spondylodiscitis.