[Effectiveness of intravenous sedation with midazolam-diphenhydramine in patients who are going to perform an magnetic resonance]. / Efectividad de la sedación intravenosa con midazolam- difenhidramina en pacientes a quienes se va a realizar una resonancia magnética (RM).

INTRODUCTION: The requirement of the anesthesiologist for patient care outside the surgical area is constantly increasing. It is an activity that encompasses the different degrees of monitoring, sedation, and anesthesia. OBJECTIVE: To compare the safety and efficacy of midazolam midazolam-diphenhydramine against magnetic resonance with level of sedation on the Ramsay scale. MATERIALS AND METHODS: We performed a study in the Instituto Mexicano del Seguro Social Obregon, Sonora, of patients scheduled for cranial magnetic resonance imaging with sedation, during October and December 2013, comparing two groups: midazolam/diphenhydramine against midazolam groups. RESULTS: We included 68 patients, 34 in the experimental group (midazolam-diphenhydramine) versus 34 controls (midazolam). The Ramsay scale showed, in the experimental group, an increased sedation effect resulting in one Ramsay 1, at 10 minutes 2.8 2.8 20 minutes and 30 minutes 2.0. In the control group the basal Ramsay was 1, 2.1 to 10 minutes, 20 minutes and 2.1 to 2.0 at 30 minutes (p = 0.0001). The analysis of heart rate, respiratory, and baseline oxygen saturation, at 10, 20 and 30 minutes, was p = 0.0001 for both groups. CONCLUSION: The combination of diphenhydramine with intravenous midazolam is safe, with the degree of sedation being better compared with use of midazolam alone, resulting in less failure of sedation during magnetic resonance imaging.

Efectos de la educación comunitaria sobre factores de riesgo en adultos mayores prediabéticos / Effects of community-based education on the risk factors in prediabetic older adults

Introducción: la educación es piedra angular en la prevención, atención y tratamiento de la diabetes mellitus. Promueve efectos positivos en la salud de los enfermos y sus familiares a través del conocimiento, con la finalidad de prevenir o retardar las complicaciones de la diabetes, por lo que ningún grupo etario debe ser excluido de este beneficio. Objetivo: determinar el efecto de la educación comunitaria sobre el sedentarismo, los hábitos alimentarios y la glucemia, en adultos mayores con prediabetes. Métodos: estudio cuasi experimental en 20 adultos mayores de ambos géneros, con glucemia capilar de 100 mg/dL a 125 mg/dL, derechohabientes del Instituto Mexicano del Seguro Social, adscritos a la Unidad de Medicina Familiar No. 17 del Instituto Mexicano del Seguro Social, en Villa Juárez, Sonora, México. Resultados: el promedio de edad fue 67 ± 6 años, con predominio del género femenino (60 %) y escolaridad baja. El 72 % de la población tenía familiares directos con diabetes mellitus. Luego de la estrategia educativa, mejoraron los conocimientos sobre diabetes, y hubo cambios significativos antes-después en la evaluación global (p= 0,0001), glucemia capilar (p= 0,0001) y hemoglobina glucosilada (p= 0,003). Así mismo, mejoraron los hábitos dietéticos y de ejercicio físico. Conclusiones: la estrategia educativa tiene un efecto benéfico sobre variables metabólicas y favorece cambios en el estilo de vida(AU)

Introduction: education is the milestone in the prevention, care and treatment of diabetes mellitus. It promotes positive effects for the patient's and the relatives' health through acquisition of knowledge for the purpose of preventing or delaying the diabetes complications, so any age group should be excluded from this benefit. Objective: to determine the effect of community-based education on sedentary and feeding habits and glycemia in pre-diabetic older adults. Methods: quasi-experimental study of 20 older adults of both sexes with capillary glycemia of 100 mg/dL a 125 mg/dL, rightful owners of the Instituto Mexicano del Seguro Social and ascribed to the family medicine unit no. 17 of Instituto Mexicano del Seguro Social in Villa Juarez, Sonora, Mexico. Results: the average age was 67 ± 6 years, females (60 percent) and low schooling prevailed. Seventy two percent of the population had first-line relatives with diabetes. After the educational strategy implementation, knowledge on diabetes improved and significant changes occurred when comparing before and after this intervention in terms of global assessment (p= 0.0001), capillary glycemia (p= 0.0001), and glycosylate hemoglobin (p= 0.003). Feeding habits and physical exercising showed some improvement. Conclusions: educational strategy has beneficial effects on the metabolic parameters and encourages lifestyle changes(AU)

[Seroprevalence of antinuclear antibodies in blood donors in the Yaqui Valley]. / Seroprevalencia de anticuerpos antinucleares en donadores de sangre del valle del Yaqui.

BACKGROUND: Antinuclear antibodies are immunoglobulins that recognize autologous nuclear and cytoplasmic cellular components. In healthy persons they are not associated with autoimmune disease. However, they may be related to an immune risk phenotype that has not been sufficiently studied. We undertook this study to examine the presence of antinuclear antibodies in serum from blood donors. METHODS: Cross-sectional study on 379 blood donors between 18 and 65 years old. Serum for the presence of antinuclear antibodies by indirect immunofluorescence in HEp-2 cells was analyzed. The prevalence and pattern of expression were compared with age, gender, and history of rheumatic or thyroid disease. RESULTS: Prevalence of antinuclear antibodies in the study population was 13%. Most of the positive subjects were between 21 and 40 years old. Male gender expressed a greater proportion of positivity (11%) than females (2%). Likewise, 82% of males had low titers (1:80) and nucleolar type in 66% of cases (OR = 10.66 [1.83 to 62.18], p = 0.007). CONCLUSIONS: The presence of antinuclear antibodies in healthy individuals at low levels may not mean an autoimmune condition; however, it could reflect exposure to environmental factors that have not been sufficiently studied. New studies of healthy individuals are necessary in order to explain the association between the presence of these antibodies and toxic and environmental factors and their effects on health.

Antecedentes: los anticuerpos antinucleares son inmunoglobulinas que reconocen componentes celulares nucleares y citoplasmáticos autólogos. En personas sanas no se relacionan con alguna enfermedad autoinmune; sin embargo, pueden estar vinculados con un fenotipo inmunológico de riesgo que no ha sido suficientemente estudiado. Objetivo: examinar la existencia de anticuerpos antinucleares en el suero de donadores de sangre. Material y métodos: estudio transversal y analítico en búsqueda de anticuerpos antinucleares en suero mediante inmunofluorescencia indirecta en células HEp-2. La prevalencia y patrón de expresión se contrastaron con la edad, el género y los antecedentes de enfermedad reumática o tiroidea. Resultados: se estudiaron 379 donadores de sangre con límites de edad entre 18 y 65 años. La prevalencia de anticuerpos antinucleares en la población estudiada fue de 13%. La mayoría de los sujetos positivos tenía entre 21 y 40 años de edad. El género masculino expresó mayor proporción de positividad (11%) en comparación con las mujeres (2%). De la misma forma, 82% de los hombres tenía títulos bajos (1:80) y en 66% eran de tipo nucleolar (RM = 10.66 [1.83 a 62.18]; p = 0.007). Conclusiones: en individuos sanos, la existencia de anticuerpos antinucleares a títulos bajos puede no significar un estado de autoinmunidad; sin embargo, podría ser el reflejo de una exposición a factores ambientales que no han sido lo suficientemente estudiados. Es necesario realizar nuevos estudios en población sana que permitan explicar la asociación entre estos anticuerpos y los factores tóxicoambientales, así como sus efectos en la salud.

[Anthropometric measures in urban child population from 6 to 12 years from the northwest of México]. / Medidas antropométricas en la población infantil urbana de 6 a 12 años del noroeste de México.

BACKGROUND: The degree of overweight-obesity varies according to the conditions of each population and depending on geographical area, race or ethnicity, socioeconomic status, and susceptibility of each individual. The aim of this study was to determine anthropometric measures in urban child population from 6 to 12 years of Ciudad Obregón, Sonora. METHODS: We studied 684 schoolchildren from 6 to 12 years of age, of both genders in the urban area of Ciudad Obregón, Sonora. We measured weight, height, arm circumference (AC), waist, and body mass index (BMI). We used descriptive statistics (frequencies, percentages), and to compare the growth charts of this study vs. the reference standards (CDC and Ramos-Galván), we employed statistical inference (Student t test). RESULTS: On average, weight, height, AC, BMI for age by gender were higher than the reference standards at all ages. Seventy-four boys (22 %) and 51 girls (14.5 %) were above 95th percentile. With regards to size, 42 children (12.6 %) were below the 5th percentile and 37 (10.5 %) above the 95th percentile. CONCLUSION: Schoolchildren in the southern zone of Sonora showed a higher anthropometric pattern than the reference standards.

INTRODUCCIÓN: el grado de sobrepeso-obesidad tendrá variaciones de acuerdo con las condiciones de cada población, según el ámbito geográfico, la raza o etnia, el status socioeconómico y la susceptibilidad de cada individuo. El objetivo de este estudio fue determinar medidas antropométricas en la población infantil urbana de 6 a 12 años de Ciudad Obregón, Sonora. MÉTODOS: se estudiaron 684 escolares de 6 a 12 años de edad, sanos y de ambos géneros de la zona urbana de Ciudad Obregón, Sonora, en quienes se midieron peso, talla, perímetro braquial (PB), cintura e índice de masa corporal (IMC). Se realizó estadística descriptiva mediante frecuencias, porcentajes, e inferencial mediante t de Student para comparar las tablas de crecimiento de Ramos Galván y las del Centro para el Control y Prevención de Enfermedades (CDC). RESULTADOS: en promedio, peso, talla, PB, IMC por edad según el género fueron superiores a los estándares de referencia en todas las edades. Setenta y cuatro niños (22 %) y 51 niñas (14.5 %) se situaron por arriba del percentil 95. Con respecto a la talla, 42 niños (12,6 %) se encontraron por abajo del percentil 5 y 37 (10.5 %) por arriba del percentil 95. CONCLUSIÓN: los escolares de la zona sur del estado de Sonora presentaron un patrón antropométrico superior a los patrones de referencia conocidos.

[Depression and state of nutrition in schoolchildren from Sonora]. / Depresión y estado de nutrición en escolares de Sonora.

BACKGROUND: Pediatric obesity has become a problem of epidemic proportions, due to the inadequate and excessive consumption of food, sedentary lifestyle, and the restricted socio-economic development. This causes a major risk in health complications that have an effect on the psychological and social spheres of the child, which makes him endure such diseases as depression and anxiety. The aim of this study was to determine the association between depression and the nutritional status of schoolchildren from a family medicine unit in Sonora. METHODS: Cross-sectional study performed during 2011 in 101 schoolchildren from Sonora. Kovacs test was applied to detect depressive symptoms; nutritional status was determined by weight and height; body mass index was calculated according to the Center for Disease Control and Prevention (CDC) percentiles. The results were analyzed in SPSS version 18 using Mann-Whitney U and chi-square. RESULTS: Of all the patients with depression, 19 were obese; the other 10 showed a normal nutrition status. Patients with low weight did not show depression. The odds ratio (OR) for depression in students with obesity was 3.16, 95 % CI = 1.13, 7.12. CONCLUSIONS: The detection and management of depression should be considered in the treatment of obesity.

INTRODUCCIÓN: la obesidad infantil se ha convertido en un problema cuyas proporciones son epidémicas, debido al consumo excesivo e inadecuado de alimentos, al sedentarismo y al limitado desarrollo socioeconómico. Esto ocasiona un mayor riesgo en complicaciones en la salud que repercuten en el ámbito psicológico y social del infante, lo cual lo lleva a padecer enfermedades como la depresión y la ansiedad. El objetivo de este estudio fue determinar la asociación entre la depresión y el estado de nutrición en escolares adscritos a una unidad de medicina familiar en Sonora. MÉTODOS: estudio transversal analítico que se llevó a cabo durante el 2011 en 101 escolares de Sonora. Se aplicó el test de Kovacs para detectar síntomas depresivos; se determinó el estado nutricional mediante peso y talla, y el cálculo del índice de masa corporal se hizo de acuerdo con los percentiles de las tablas del Centro para el Control y la Prevención de Enfermedades (CDC, por sus siglas en inglés) de Atlanta. El análisis de los resultados se realizó con U de Mann-Whitney y chi cuadrada en el programa SPSS, versión 18. RESULTADOS: del total de pacientes con depresión, 19 presentaron obesidad y el resto presentó estado de nutrición normal (10); los pacientes con bajo peso no presentaron depresión. La razón de momios para depresión en escolares con obesidad fue de 3.16 con un IC al 95 % de 1.13; 7.12. CONCLUSIÓN: la detección y manejo de depresión debe ser considerada dentro del tratamiento de la obesidad.

Factores de riesgo para hipertensión arterial en escolares del noroeste de México / Risk factors for hypertension among school-age children in the northwest of Mexico

Introducción: Estudios epidemiológicos han demostrado que la hipertensión arterial sistémica (HTAS) puede comenzar desde los primeros años de vida. El objetivo de este estudio fue determinar la prevalencia de HTAS y factores de riesgo (FR) en escolares de una comunidad en el noroeste de México. Material y métodos: Estudio polietápico, aleatorizado en escolares sanos de 6 a 12 años de edad. Medición de presión arterial (PA) y variables antropométricas (VA). Se consideró HTAS cuando la PA con relación a talla fuera ≥ al porcentil 95 en tablas locales (TL) y Task Force (TF). Evaluación de los FR mediante cuestionario aplicado a padres y alumnos. Resultados: En 684 niños, 51.3% mujeres y 46.8% hombres, la prevalencia de HTAS según TF fue de 7.74% y 2.63% con TL. Se observó una asociación entre PA con VA. El peso y la edad son FR para PAS, en cambio el peso sólo para PAD. Conclusiones: La prevalencia de HTAS fue similar a reportes en la literatura según TL, pero se encuentra aumentada según el TF. Hubo correlación directa entre la PA con VA y resultaron como FR para HTAS el peso y edad.

Introduction:Epidemiological studies have shown that arterial hypertension can start since the first years of life. The aim of this study was to determine the prevalence of hypertension and risk factors (RF) among school-age children from one community in the northwest of Mexico. Material and methods: A poly-stage, randomized study was carried out in healthy pupils aged 6 to 12 years old. Blood pressure (BP) and anthropometrical variables were measured. Hypertension was considered whenever BP in relation to body height was ≥ 95 percentil in local tables (LT) and task force (TF). RF was assessed using a questionnaire applied to parents and students. Results: In 684 children, 51.3% females and 46.8% males, the prevalence of hypertension according to TF was 7.74% and 2.63% according to LT. An association between hypertension and anthropometrical variables was observed. Weight and age are RF for systolic hypertension, while weight was RF for diastolic hypertension. Conclusion: Hypertension prevalence according to LT was similar to the one reported in other studies; however, it is increased according to TF. There was a direct correlation between hypertension and anthropometrical variables. Weight and age were RF for hypertension.

[Transcutaneous electrical nervous stimulation in the prognosis of Bell's palsy]. / Estimulación nerviosa eléctrica transcutánea para el pronóstico de parálisis de Bell.

BACKGROUND: The peripheral face palsy (PFP) is the commonest acute cranial neuropathy. The PFP has a showy clinical pattern which contrasts with a favorable course. Our objective was to determine the sensitivity and specificity for the nervous excitability test (NET) with transcutaneous electrical nerve stimulation (TENS) and the time required to obtain face symmetry. METHODS: An analytical cross-sectional study was made in 22 patients with PFP. The goal was the time (days) to obtain face symmetry. The sensitivity and specificity was carried out. RESULTS: A sensitivity and specificity of the NET was of 100 %. The correlation corrected by sex and age between both variables was 0.89. The average in days of recovery was smaller in those with a positive NET (p < 0.05) test. CONCLUSIONS: The test of nervous excitability for PFP with TENS is safe and simple to use in primary care and urgencies services.

[The cross-sectional area of the median nerve by sonography in the diagnosis of carpal tunnel syndrome]. / Determinación ultrasonográfica del área de corte transversal del nervio mediano en síndrome del túnel carpiano.

OBJECTIVE: To measure the median nerve cross-sectional area (MNCSA) at the carpal tunnel (CT) level by sonography (S) in a Mexican population. METHODS: A comparative cross-sectional design study with a nonprobabilistic sampling with 50 women and 50 men in good health were submitted for measuring MNCSA at the level of the CT. Other variables like sex; side and degree of daily hand activity were also studied. The analysis was made by descriptive statistics, and Mann-Whitney U or Kruskal-Wallis tests. RESULTS: The mean MNCSA was 0.063 +/- 0.015 cm(2), in women; in men it was 0.072 +/- 0.018 cm(2); the difference was significant (p < 0.004). The median MNCSA among women was 0.062 cm(2) in the right side and 0.060 cm(2) in the left (90th percentile for both hands of 0.084 cm(2)); in men, it was of 0.070 cm(2) in the right hand and of 0.069 cm(2) in the left (90th percentile for both hands of 0.097 cm(2)). The difference between women and men was significant in each side, but not between right and left hands (p = 0.21). There was no correlation between age and MNCSA on either side, or with hand activity. CONCLUSIONS: A MNCSA value of 0.1 cm(2) for men and 0.09 cm(2) for women is proposed as a standard parameter for the Mexican population.

[Acromial osteophyte in shoulder impingement syndrome. Diagnosis and prevalence]. / Osteofito acromial en el síndrome de pinzamiento de hombro. Diagnóstico y prevalencia.

INTRODUCTION: The shoulder impingement syndrome (SIS) is caused by the compression of the rotator cuff tendon tear and the subacromial bursa between the humeral head and the structures that conforms the subacromial arc. OBJECTIVE: To determine a proportion of the acromial spur in the SIS comparing it with the general population. A second one would be to evaluate the quality of the radiological technique. MATERIAL AND METHODS: A comparative cross-sectional study was made in 148 patients, divided in two groups: one conformed by 52 persons, for patients with SIS and the other, conformed by 96, for the general population of similar age. The technique used to detect the acromial spur was the anteroposterior shoulder plate with a ray at 30 degrees in caudal direction in a bilateral way that was blindly interpreted by an orthopedist in two occasions, obtaining a high concordance index of Kappa of 0.90. The criteria to consider positive spur was that the bone growth could exceed a prolongation of an imaginary line at the inferior edge of the clavicle. RESULTS: The average age in both groups was of 48.7 years +/- 14.5 years for the patients with SIS, and of 43.2 years +/- 12.9 for the patients of the control group. It was founded that 84.6% of the patients with SIS had acromial spur and in the ones of the control group, it was founded in a 36%, being this difference significant with OR of 9.3 times more frequent to have spur in patients with SIS. The quality of the technique was good in 92% of the Rx. CONCLUSION: The frequency of spur in SIS is high (84.6%), but it calls our attention that the frequency in general population was moderate (36%).

[Community-acquired pneumonia: risk focus and family functionality]. / Neumonía adquirida en la comunidad. Enfoque de riesgo y funcionalidad familiar.

INTRODUCTION: Community-acquired pneumonia is one of the five most prevalent causes of death worldwide; in Mexico, it accounts for more than 10% of the hospital admissions. OBJECTIVE: To identify the risk factors and the kind of family functionality associated to community-acquired pneumonia among adult patients. MATERIAL AND METHODS: With the prior authorization of the research and bioethics committees, a study of cases and controls took place, where both groups were asked about the following variables: alcohol consumption or active smoking, conditions of house and family functionality, anti-flu and anti-pneumococcal vaccination, disablement, and chronic pulmonary disease, among others. RESULTS: It was found that the significant variables were active smoking, disablement, pulmonary emphysema, chronic bronchitis, overcrowding at home, and alcohol consumption; and with a protective effect for this disease: a functional family and anti-pneumococcal vaccination. CONCLUSION: There are risk factors that predispose the development of community-acquired pneumonia, and that allow us to make a population profile in which some preventive strategy could diminish the frequency and lethality of this disease.

[Chronic complications of diabetes mellitus. What is the prevalence of diabetes in a family medical unit?]. / Complicaciones crónicas en la diabetes mellitus. Prevalencia en una unidad de medicina familiar.

INTRODUCTION: The role of the family doctor in fundamental in the prevention of diabetic complications, because these complications will be minor if there is good glycemic control during life. OBJECTIVE: Determine the frequency of late complications of diabetes mellitus (DM) among IMSS-insured population in Ciudad Obregón, Sonora, México. MATERIALS AND METHODS: A retrospective analysis included 252 diabetic patients selected by a systematized and stratified randomized sampling including all patient files available in the Family Medicine Unit 1 in Ciudad Obregón, Sonora. The information was taken from the clinical charts got by family physicians and specialists. We used descriptive statistics and correlation of Pearson looking for the association between glicemia's level and enough time to produce complications. RESULTS: Arterial hypertension was found in 168 cases (67%), hypertriglyceridemia in 148 (59.4%), neuropathy in 106 (42.6%), hypercholesterolemia in 89 (35.7%), retinopathy in 69 (27.5%), nephropathy in 51 (20.5%), diabetic foot in 27 (10.8%), ischemic cardiopathy in 25 (10%), cerebral thrombosis in 11 (4.4%). The period between DM diagnosis and the appearance of complications was 3.2 to 13.1 years. The correlations were high and significant in every complication. CONCLUSIONS: The frequency of DM complications in this study was very high, with an increasing tendency of developing complications throughout the time.