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1.
Int J Food Sci Nutr ; 63(4): 431-9, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22098476

RESUMO

Garlic (Allium sativum L) has distinct nutritional profile with special reference to its bioactive components and is used in different diet-based therapies to cure various lifestyle-related disorders. For this purpose, characterization and extraction of garlic were carried out followed by antioxidant assays. Different solvents (50% aqueous ethanol, 50% aqueous methanol and water) at different time intervals (4, 5 and 6 h) at 60°C were used to optimize aqueous extraction efficiency of garlic. Among the solvents, water extract resulted in better extraction yield (31.85 ± 2.09 g/25 g) at 5 h. The antioxidant potential of all these solvents was estimated through in vitro studies. In this context, it was observed that higher amount of total phenolic contents was present in aqueous methanol 71.87 ± 1.69% at 45 min. Antiradical (1,1-diphenyl-2-picrylhydrazyl assay) and antioxidant activity showed that the maximum value was 73.80 ± 3.69 and 83.83 ± 0.16%, respectively, in methanolic extract at 45 min while glucose diffusion and ferric reducing antioxidant power were 97.00 ± 0.20 and 32.66 ± 0.72% at p < 0.05, respectively. Aqueous garlic extract was selected as the best treatment on the basis of percentage yield and safety modulation in human body absorption. Aqueous garlic extract was subjected to pH, acidity, total soluble solids (TSS) and colour. It was observed that the pH of aqueous garlic extract decreased with the passage of time while acidity increased. It was also concluded that storage affected the value of TSS and colour significantly. L* values for colour on 0 day were 34.18 ± 0.08, whereas those on 28th day were 38.84 ± 0.03. It was predicted that 28 days storage resulted in significant increase in L* value, while a* value decreased from 4.31 ± 0.01 to 0.32 ± 0.01 at the end of storage study.


Assuntos
Antioxidantes/farmacologia , Alho/química , Fenóis/farmacologia , Extratos Vegetais/farmacologia , Antioxidantes/análise , Compostos de Bifenilo/metabolismo , Cor , Compostos Férricos/metabolismo , Glucose/metabolismo , Humanos , Concentração de Íons de Hidrogênio , Fenóis/análise , Picratos/metabolismo , Extratos Vegetais/química , Raízes de Plantas/química
2.
Eur J Nutr ; 47(2): 68-79, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18301937

RESUMO

This review is intended to focus on the composition of oat and its therapeutic potential in the pharmacology that supports its use to cure various maladies. Oat (Avena sativa) is distinct among the cereals due to its multifunctional characteristics and nutritional profile. Recent advancement in food and nutrition has revealed the importance of its various components. It is a good source of dietary fiber especially beta-glucan, minerals and other nutrients. Oat and oat by products have been proven to be helpful in the treatment of diabetes and cardiovascular disorders. Oat bran in particular, is good source of B complex vitamins, protein, fat, minerals besides heart healthy soluble fiber beta-glucan. The beta-glucan has outstanding functional properties and is of immense importance in human nutrition. Different physiological effects of beta-glucan are related to its viscosity, attenuation of postprandial plasma glucose and insulin responses, high transport of bile acids towards lower parts of the intestinal tract and high excretion of bile acids thereby lowering of serum cholesterol levels. Moreover, it is helpful against coeliac disease. The incorporation of oat grains and oat bran in the food products improves not only the nutrition but also a therapy against various maladies.


Assuntos
Avena , Glicemia/metabolismo , Fibras na Dieta/metabolismo , beta-Glucanas/metabolismo , Área Sob a Curva , Avena/química , Avena/fisiologia , Glicemia/efeitos dos fármacos , Doença Celíaca/dietoterapia , Colesterol/metabolismo , Diabetes Mellitus Tipo 2/dietoterapia , Fibras na Dieta/análise , Humanos , Hipercolesterolemia/dietoterapia , Absorção Intestinal , Minerais/análise , Período Pós-Prandial , Solubilidade , Viscosidade , Vitaminas/análise , beta-Glucanas/análise
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