Aggressive adenomatoid odontogenic tumor of mandible showing root resorption: A histological case report.

Adenomatoid odontogenic tumor (AOT) is a benign odontogenic tumor with slow but progressive growth. The three variants: Follicular, extra follicular (both central type), and peripheral present with identical histologic findings. This case report describes a patient with a large AOT in the mandible of the extra follicular type which is the less common of the two central types. It also strikes as an unusual case as it shows significant root resorption of the involved displaced teeth which is not generally reported in AOT's.

Invasive aspergillosis in an immunocompetent host.

Aspergillosis is a common opportunistic fungal infection affecting the nose and paranasal sinuses. The disease presents in various forms ranging from non-invasive to invasive, destructive and allergic types. We report here a rare case of invasive aspergillosis in an immunocompetent host with the literature review.

Determination of levels of salivary IgA subclasses in patients with minor recurrent aphthous ulcer.

CONTEXT: Recurrent Aphthous Ulcer (RAU) is an inflammatory disease characterized by recurrent, painful oral ulcers. It is of multifactorial etiology. Salivary immunoglobulins have important role in the protection of mucosal surfaces. AIM: The aim of this study was to determine salivary immunoglobulin A1 (IgA1) and IgA2 in acute and remission phases of the disease. MATERIALS AND METHODS: Thirty clinically confirmed cases of RAU and 30 age-and sex-matched controls were included in the study. After detailed case history and thorough clinical examination, 2 mL of saliva was collected in both acute and remission phases of the disease. The obtained saliva samples were subjected to quantification of IgA1 and IgA2 levels using RID kit. RESULTS: The mean IgA2 level was significantly higher (P<.001) in both acute and remission phase of the study group. The mean IgA1 level also showed a significant increase in the acute phase compared to remission as well as controls (P<.05). Females exhibited a higher level in acute phase for IgA1 and in both phases for IgA2 (P<.05). CONCLUSION: The results associated with clinical observations suggest that acute phase is characterized with increase in IgA2 that might reflect increased immune response as a possible result of the microbial stimulation seen in the acute phase in comparison to the remission period. IgA plays an important role in the pathogenesis of RAU and it can be used as a parameter to assess the mucosal immune status.