Computational modeling of human multisensory spatial representation by a neural architecture.

Our brain constantly combines sensory information in unitary percept to build coherent representations of the environment. Even though this process could appear smooth, integrating sensory inputs from various sensory modalities must overcome several computational issues, such as recoding and statistical inferences problems. Following these assumptions, we developed a neural architecture replicating humans' ability to use audiovisual spatial representations. We considered the well-known ventriloquist illusion as a benchmark to evaluate its phenomenological plausibility. Our model closely replicated human perceptual behavior, proving a truthful approximation of the brain's ability to develop audiovisual spatial representations. Considering its ability to model audiovisual performance in a spatial localization task, we release our model in conjunction with the dataset we recorded for its validation. We believe it will be a powerful tool to model and better understand multisensory integration processes in experimental and rehabilitation environments.

UNet and MobileNet CNN-based model observers for CT protocol optimization: comparative performance evaluation by means of phantom CT images.

Purpose: The aim of this work is the development and characterization of a model observer (MO) based on convolutional neural networks (CNNs), trained to mimic human observers in image evaluation in terms of detection and localization of low-contrast objects in CT scans acquired on a reference phantom. The final goal is automatic image quality evaluation and CT protocol optimization to fulfill the ALARA principle. Approach: Preliminary work was carried out to collect localization confidence ratings of human observers for signal presence/absence from a dataset of 30,000 CT images acquired on a PolyMethyl MethAcrylate phantom containing inserts filled with iodinated contrast media at different concentrations. The collected data were used to generate the labels for the training of the artificial neural networks. We developed and compared two CNN architectures based respectively on Unet and MobileNetV2, specifically adapted to achieve the double tasks of classification and localization. The CNN evaluation was performed by computing the area under localization-ROC curve (LAUC) and accuracy metrics on the test dataset. Results: The mean of absolute percentage error between the LAUC of the human observer and MO was found to be below 5% for the most significative test data subsets. An elevated inter-rater agreement was achieved in terms of S-statistics and other common statistical indices. Conclusions: Very good agreement was measured between the human observer and MO, as well as between the performance of the two algorithms. Therefore, this work is highly supportive of the feasibility of employing CNN-MO combined with a specifically designed phantom for CT protocol optimization programs.

Unsupervised Synthetic Acoustic Image Generation for Audio-Visual Scene Understanding.

Acoustic images are an emergent data modality for multimodal scene understanding. Such images have the peculiarity of distinguishing the spectral signature of the sound coming from different directions in space, thus providing a richer information as compared to that derived from single or binaural microphones. However, acoustic images are typically generated by cumbersome and costly microphone arrays which are not as widespread as ordinary microphones. This paper shows that it is still possible to generate acoustic images from off-the-shelf cameras equipped with only a single microphone and how they can be exploited for audio-visual scene understanding. We propose three architectures inspired by Variational Autoencoder, U-Net and adversarial models, and we assess their advantages and drawbacks. Such models are trained to generate spatialized audio by conditioning them to the associated video sequence and its corresponding monaural audio track. Our models are trained using the data collected by a microphone array as ground truth. Thus they learn to mimic the output of an array of microphones in the very same conditions. We assess the quality of the generated acoustic images considering standard generation metrics and different downstream tasks (classification, cross-modal retrieval and sound localization). We also evaluate our proposed models by considering multimodal datasets containing acoustic images, as well as datasets containing just monaural audio signals and RGB video frames. In all of the addressed downstream tasks we obtain notable performances using the generated acoustic data, when compared to the state of the art and to the results obtained using real acoustic images as input.

Addressing signal alterations induced in CT images by deep learning processing: A preliminary phantom study.

PURPOSE: We investigate, by an extensive quality evaluation approach, performances and potential side effects introduced in Computed Tomography (CT) images by Deep Learning (DL) processing. METHOD: We selected two relevant processing steps, denoise and segmentation, implemented by two Convolutional Neural Networks (CNNs) models based on autoencoder architecture (encoder-decoder and UNet) and trained for the two tasks. In order to limit the number of uncontrolled variables, we designed a phantom containing cylindrical inserts of different sizes, filled with iodinated contrast media. A large CT image dataset was collected at different acquisition settings and two reconstruction algorithms. We characterized the CNNs behavior using metrics from the signal detection theory, radiological and conventional image quality parameters, and finally unconventional radiomic features analysis. RESULTS: The UNet, due to the deeper architecture complexity, outperformed the shallower encoder-decoder in terms of conventional quality parameters and preserved spatial resolution. We also studied how the CNNs modify the noise texture by using radiomic analysis, identifying sensitive and insensitive features to the denoise processing. CONCLUSIONS: The proposed evaluation approach proved effective to accurately analyze and quantify the differences in CNNs behavior, in particular with regard to the alterations introduced in the processed images. Our results suggest that even a deeper and more complex network, which achieves good performances, is not necessarily a better network because it can modify texture features in an unwanted way.