Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 6 de 6
Filtrar
1.
J Adv Prosthodont ; 16(2): 77-90, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38694191

RESUMO

PURPOSE: The study aims to investigate the influence of the ferrule effect and types of posts on the stress distribution in three morphological types of the maxillary central incisor. MATERIALS AND METHODS: Nine models were created for 3 maxillary central incisor morphology types: "Fat" type - crown 12.5 mm, root 13 mm, and buccolingual cervical diameter 7.5 mm, "Medium" type - crown 11 mm, root 14 mm, and buccolingual cervical diameter 6.5 mm, and "Slim" type - crown 9.5 mm, root 15 mm, and buccolingual cervical diameter 5.5 mm. Each model received an anatomical castable post-and-core or glass-fiber post with resin composite core and three ferrule heights (nonexistent, 1 mm, and 2 mm). Then, a load of 14 N was applied at the cingulum with a 45° slope to the long axis of the tooth. The Maximum Principal Stress and the Minimum Principal Stress were calculated in the root dentin, crown, and core. RESULTS: Higher tensile and compression stress values were observed in root dentin using the metallic post compared to the fiber post, being higher in the slim type maxillary central incisor than in the medium and fat types. Concerning the three anatomical types of maxillary central incisors, the slim type without ferrule height in mm presented the highest tensile stress in the dentin, for both types of metal and fiber posts. CONCLUSION: Post system and tooth morphology were able to modify the biomechanical response of restored endodontically-treated incisors, showing the importance of personalized dental treatment for each case.

2.
Stem Cells Dev ; 31(15-16): 498-505, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35730119

RESUMO

Paracrine factors secreted in the conditioned media (CMs) of periodontal ligament-derived stem cells (PDLSCs) have been shown to downregulate inflammatory effects of interleukin (IL)-1ß on chondrocytes wherein milk fat globule-epidermal growth factor 8 (MFG-E8) is one of the PDLSCs' highly secretory proteins. Therefore, the objective of this study was to investigate the ability of PDLSC CMs and MFG-E8 to reduce the inflammatory effects of impact injury on porcine talar articular cartilage (AC) and IL-1ß on chondrocytes, respectively. Stem cells were isolated from human periodontal ligaments. The MFG-E8 content in CM collected at 5% and 20% oxygen was measured by ELISA assay and compared across subcultures and donors. AC samples were divided into three groups: control, impact, and impact+CM. Chondrocytes were isolated from pig knees and were divided into three groups: control, IL-1ß, and IL-1ß+MFG-E8. Gene expression data were analyzed by reverse transcription-polymerase chain reaction. It was found that impact load and IL-1ß treatment upregulated IL-1ß, TNF-α, ADAMTS-4, and ADAMTS-5 gene expression in AC and chondrocytes, respectively. PDLSCs-CM prevented the upregulation of all four genes due to impact, whereas MFG-E8 prevented upregulation of IL-1ß, ADAMTS-4, and ADAMTS-5 in chondrocytes, but it did not prevent TNF-α upregulation. There were no significant differences in MFG-E8 content in CM among oxygen levels, passage numbers, or donors. The findings suggested that MFG-E8 is an effective anti-inflammatory agent contributing to the chondroprotective effects of PDLSCs-CM on acutely injured AC. Thus, introducing PDLSCs-CM to sites of acute traumatic AC injury could prevent the development of post-traumatic osteoarthritis.


Assuntos
Cartilagem Articular , Proteínas do Leite , Animais , Antígenos de Superfície/metabolismo , Cartilagem Articular/metabolismo , Meios de Cultivo Condicionados/farmacologia , Humanos , Proteínas do Leite/genética , Proteínas do Leite/metabolismo , Oxigênio , Ligamento Periodontal/metabolismo , Células-Tronco/metabolismo , Suínos , Fator de Necrose Tumoral alfa
3.
J Prosthodont ; 28(6): 677-683, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31149753

RESUMO

PURPOSE: To investigate the effect of the location of a partial ferrule on 2 walls and the influence of ferrule height variations on remaining walls, fracture resistance, and failure mode of maxillary incisors endodontically treated and restored with fiber posts. MATERIALS AND METHODS: Sixty intact human maxillary central incisors were divided into 6 groups (n = 10): no ferrule (NF), 2-mm ferrule (CF2), absence of lingual wall and 1 proximal wall with remaining walls' height, 1 mm (IF1), 2 mm (IF2), 3 mm (IF3), and 4 mm (IF4). They were restored with a fiberglass post and composite resin core. Complete metal crowns were then cemented on all specimens. Completed specimens were subjected to thermal cycling (6000 cycles, 5°C/55°C) followed by the immediate testing of fracture resistance. After failure, the specimens were sectioned buccolingually and evaluated to identify the mode of failure. The data were analyzed with an ANOVA and the Student-Newman-Keuls multiple comparison tests (α = 0.05). RESULTS: An incomplete ferrule (IF2) with the lingual wall missing and 1 proximal wall had a fracture resistance of 494 ± 137 N, which was significantly less that of a complete ferrule (CF2) (707 ± 162 N, p = 0.002). An increase of 3 to 4 mm in height of the remaining walls had negligible influence on the fracture resistance: 514 ± 117 N (IF3), 557 ± 177 N (IF4). Partial decementation was observed in all specimens of IF3 and IF4, in 9 of IF1 and IF2, in 6 in NF, and in 3 in CF2. Root fractures occurred in 7 specimens, 4 in CF2, 1 in IF1, 1 in IF2, and 1 in IF4. Cracks under the cemento-enamel junction occurred in 4 specimens (NF and IF1), in 5 (IF2 and IF3), and in 6 (CF2 and IF4) and were considered catastrophic failures. CONCLUSIONS: Specimens with a complete ferrule of 2 mm height were more resistant to fracture than specimens with 2 mm height and absence of the lingual wall and 1 proximal wall. A 3 or 4 mm wall height increase was associated with an insignificant increase in fracture resistance and cannot compensate for the absence of the lingual wall and 1 proximal wall.


Assuntos
Técnica para Retentor Intrarradicular , Fraturas dos Dentes , Dente não Vital , Resinas Compostas , Coroas , Falha de Restauração Dentária , Análise do Estresse Dentário , Humanos , Incisivo
4.
J Prosthet Dent ; 119(3): 390-396, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28756865

RESUMO

STATEMENT OF PROBLEM: Limited information is available on the effect of an incomplete ferrule because of the varying residual axial wall heights and the volume of residual tooth structure on the fracture resistance of endodontically treated and restored maxillary incisors. PURPOSE: The purpose of this in vitro investigation was to examine the effect of varying residual axial wall heights, residual coronal tooth structure, and the absence of 1 proximal axial wall on the fracture resistance and failure mode of endodontically treated teeth restored with metal posts. MATERIAL AND METHODS: Sixty intact human maxillary central incisors were divided into 6 groups (n=10): no ferrule (NF), 2-mm complete ferrule (CF2), 2-mm (IF2), 3-mm (IF3), and 4-mm (IF4) incomplete ferrules missing a single interproximal wall, and a control group that had a 6-mm incomplete ferrule (IF6). Cast metal post-and-cores were placed in all experimental specimens except for controls. Control specimens received 1 interproximal cavity preparation extending to the root canal access and a composite resin restoration. Complete metal crowns were then cemented on all specimens. Completed specimens were subjected to thermocycling (6000 cycles, 5°C/55°C) followed by the immediate testing of fracture resistance. Failed specimens were sectioned buccolingually and evaluated to identify the failure mode. The data were analyzed with an analysis of variance (ANOVA) and the Student-Newman-Keuls multiple comparison test (α=.05). RESULTS: An incomplete ferrule (IF2) with 1 interproximal wall missing had significantly reduced fracture resistance (697 N) compared with a complete ferrule (932 N). An increase of 3 to 4 mm of remaining wall height improved fracture resistance, from 844 N (IF3) to 853 N (IF4). Partial decementation was noticed in 8 NF and 5 IF2 specimens. IF3 and IF4 had no decementations. Radicular fractures and cracks (catastrophic failure) were observed in all IF2, IF3, and IF4, 9 CF2, and 6 NF specimens. In 7 specimens without posts (IF6, control), composite resin foundation and/or coronal dentin fracture were observed and the failure was considered repairable. CONCLUSIONS: The results of this in vitro study indicated that specimens with a 2-mm ferrule of uniform height were more resistant to fracture than specimens with a 2-mm ferrule and 1 missing interproximal wall. An increased wall height of 3 or 4 mm was associated with a significant increase in fracture resistance and can compensate for the missing interproximal wall.


Assuntos
Planejamento de Prótese Dentária , Incisivo , Fraturas dos Dentes , Dente não Vital , Estudos de Casos e Controles , Coroas , Falha de Restauração Dentária , Análise do Estresse Dentário , Humanos , Técnica para Retentor Intrarradicular
6.
In. Santos Pantaleón, Domingo. Odontología clínica práctica contemporánea. Santo Domingo, IOES, 2001. p.17-54, ilus.
Monografia em Espanhol | LILACS, BBO - Odontologia | ID: lil-303997
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA