Understanding the effects of a sudden directional shift in somatosensory feedback and increasing task complexity on postural adaptation in individuals with and without chronic ankle instability.

BACKGROUND: Individuals with chronic ankle instability (CAI) present somatosensory dysfunction following an initial ankle sprain. However, little is known about how individuals with CAI adapt to a sudden sensory perturbation of instability with increasing task and environmental constraints to maintain postural stability. METHODS: Forty-four individuals with and without unilateral CAI performed the Adaptation Test to a sudden somatosensory inversion and plantarflexion perturbations (environment) in double-, injured-, and uninjured- limbs. Mean sway energy scores were analyzed using 2 (group) × 2 (somatosensory perturbations) × 3 (task) repeated measures analysis of variance. RESULTS: There were significant interactions between the group, environment, and task (P=.025). The CAI group adapted faster than healthy controls to a sudden somatosensory inversion perturbation in the uninjured- (P=.002) and injured- (P<.001) limbs, as well as a sudden somatosensory plantarflexion perturbation in the double- (P=.033) and uninjured- (P=.035) limbs. The CAI and healthy groups presented slower postural adaptation to a sudden inversion perturbation than a sudden somatosensory plantarflexion perturbation in double-limb (P<.001). Whereas both groups demonstrated faster postural adaptation to a sudden somatosensory inversion perturbation compared to somatosensory plantarflexion perturbation while maintaining posture in the injured- (P<.001) and uninjured- (P<.001) limbs. The CAI and healthy groups adapted faster to a sudden somatosensory inversion perturbation in the injured- (P<.001) and uninjured- (P<.001) limbs than in double-limb, respectively. DISCUSSION: Postural adaptation in individuals with and without CAI depended on environmental (somatosensory perturbations) and task constraints. The CAI group displayed comparable and faster postural adaptation to a sudden somatosensory inversion and plantarflexion in double-, injured-, and uninjured- limbs, which may reflect a centrally mediated alteration in neuromuscular control in CAI.

Sensory Reweighting System Differences on Vestibular Feedback with Increased Task Constraints in Individuals with Chronic Ankle Instability Compared to Healthy Controls.

CONTEXT: Chronic ankle instability (CAI) is associated with a less flexibly adaptable sensorimotor system. Thus, individuals with CAI may present an inadequate sensory reweighting system inhibiting the ability to emphasize weight on reliable sensory feedback to control posture. However, how individuals with CAI reweight sensory feedback to maintain postural control in bilateral and unilateral stances has yet to be established. OBJECTIVES: The primary purpose was to examine group differences in how the sensory reweighting system changes to control posture in a simple double-limb stance and a more complex single-limb stance (uninjured-limb, injured-limb) under increased environmental constraints manipulating somatosensory and visual information for individuals with and without CAI. The secondary purpose was to examine the effect of environmental and task constraints on postural control. STUDY DESIGN: Case-control study. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: 21 individuals with CAI (26.4±5.7years, 171.2±9.8cm, 76.6±15.17kg) and 21 healthy controls (25.8±5.7years, 169.5±9.5cm, 72.4±15.0kg) participated in the study. MAIN OUTCOME MEASURE(S): Equilibrium10 were examined while completing 6 environmental conditions of the Sensory Organization Test (SOT) during 3 tasks (double-limb and single-limb [uninjured, injured] stances). Sensory reweighting ratios for sensory systems (somatosensory, vision, vestibular) were computed from paired Equilibrium10. RESULTS: Significant 3-factor interactions were found between group, sensory systems, and tasks (P=0.006) and for groups, task, and environment (P=0.007). The CAI group failed to downweight vestibular feedback compared to healthy controls while maintaining posture in the injured-limb (P=0.030). The CAI group displayed better postural stability than healthy controls while standing with absent vision, fixed surroundings, and a moving platform in the injured-limb (P=0.032). CONCLUSIONS: The CAI group relied on vestibular feedback while maintaining better postural stability than healthy controls in the injured-limb. Group differences in postural control depended on both environmental (absent vision, moving platform) and task (injured-limb) constraints.

The Impact of Differential Knee Laxity on Brain Activation During Passive Knee Joint Loading.

Although higher anterior knee laxity is an established risk factor of ACL injury, underlying mechanisms are uncertain. While decreased proprioception and altered movement patterns in individuals with anterior knee laxity have been identified, the potential impact of higher laxity on brain activity is not well understood. Thus, the purpose of this study is to identify the impact of different magnitudes of knee laxity on brain function during anterior knee joint loading. Twenty-seven healthy and active female college students without any previous severe lower leg injuries volunteered for this study. Anterior knee laxity was measured using a knee arthrometer KT-2000 to assign participants to a higher laxity (N=15) or relatively lower laxity group (N=12). Functional magnetic resonance images were obtained during passive anterior knee joint loading in a task-based design using a 3T MRI scanner. Higher knee laxity individuals demonstrated diminished cortical activation in the left superior parietal lobe during passive anterior knee joint loading. Less brain activation in the regions associated with awareness of bodily movements in females with higher knee laxity may indicate a possible connection between brain activity and knee laxity. The results of this study may help researchers and clinicians develop effective rehabilitation programs for individuals with increased knee laxity. This article is protected by copyright. All rights reserved.

Sex-Specific Brain Activations during Single-Leg Exercise.

Background: Females have an increased incidence of musculoskeletal injuries compared to males. Sex differences in neuromuscular control has been widely studied regarding the dynamics and muscle activity during preplanned movements. While muscle activation patterns and movement biomechanics are understood to differ between sexes, it is not well understood how sex influences brain activity for lower extremity movement. Since the brain plays a vital role for voluntary movement and joint stability, it is important to understand the sex differences in brain function in order to better understand neuromuscular control associated with increased musculoskeletal injury risk in female. Hypothesis/Purpose: The purpose of this study is to understand the differences in brain activation patterns between sexes during a simple active knee extension-flexion movement. It was hypothesized that females would demonstrate higher cortical activation in the somatosensory areas compared to males as a compensatory strategy. Study Design: Cross-Sectional Study. Methods: Thirteen males and seventeen females who were healthy and physically active participated in this study (Male: 23.7±3.8 years, 74.5±13.5 kg, 172.3±6.4 cm; Female: 20.6±1.6 years, 65.4±12.8 kg, 163±6.1 cm). Functional magnetic resonance imaging data were obtained during a simple left knee extension-flexion exercise with their own leg weight while lying on the MRI table. The blood oxygen level dependent (BOLD) signals were compared between sexes. Results: There was significantly greater activation in the visual cortices and premotor cortex in females compared to males during the studied movement. Males demonstrated significantly greater activation in the right cerebellum. Conclusion: The results revealed sex differences in BOLD signal during simple knee extension-flexion movement. The results suggest that sex may be a biological factor in understanding brain activity associated with knee motor control. Level of Evidence: Level 3.

Practice-Not Task Difficulty-Mediated the Focus of Attention Effect on a Speed-Accuracy Tradeoff Task.

External focus (attention to the movement effect) has been found effective in motor performance and learning. However, while some investigators have suggested that the effect of attentional focus varies with task difficulty, others reported external focus benefits regardless of difficulty. We hypothesized that attentional focus effects would vary with practice, due to changes in the individual's processing efficiency. We had three 20-person participant groups (external focus instructions, internal focus instructions, control) practice three difficulty levels of a Fitts reciprocal tapping task over two days. Participants in the external/internal focus groups were instructed to "mentally focus on moving the pen/your hand as fast and accurately as possible," while control participants were instructed to "mentally focus only on doing your best to achieve the task goal." We then analyzed the effect of attentional focus by task difficulty at the initial performance (the beginning of the practice) and after learning (the retention/transfer phase), using movement time (MT) and number of error taps (Err) as performance measures. The internal focus group made more errors than the control group only at the retention/transfer phase. We found no error differences between the external and internal focus groups, and there were no MT differences between any groups. Our primary hypothesis about the differential effect of attentional focus by practice was supported. The attentional focus effect on Err differed in the retention/transfer phase from the immediate phase, suggesting that practice mediated the attentional focus effect. We discuss how information theory may supplement understanding of attentional focus interventions in motor skill acquisition.

Ankle Dorsiflexion Affects Hip and Knee Biomechanics During Landing.

BACKGROUND: Restricted ankle dorsiflexion range of motion (DFROM) has been linked to lower extremity biomechanics that place an athlete at higher risk for injury. Whether reduced DFROM during dynamic movements is due to restrictions in joint motion or underutilization of available ankle DFROM motion is unclear. HYPOTHESIS: We hypothesized that both lesser total ankle DFROM and underutilization of available motion would lead to high-risk biomechanics (ie, greater knee abduction, reduced knee flexion). STUDY DESIGN: Cross-sectional study. LEVEL OF EVIDENCE: Level 3. METHODS: Nineteen active female athletes (age, 20.0 ± 1.3 years; height, 1.61 ± 0.06 m; mass, 67.0 ± 10.7 kg) participated. Maximal ankle DFROM (clinical measure of ankle DFROM [DF-CLIN]) was measured in a weightbearing position with the knee flexed. Lower extremity biomechanics were measured during a drop vertical jump with 3-dimensional motion and force plate analysis. The percent of available DFROM used during landing (DF-%USED) was calculated as the peak DFROM observed during landing divided by DF-CLIN. Univariate linear regressions were performed to identify whether DF-CLIN or DF-%USED predicted knee and hip biomechanics commonly associated with injury risk. RESULTS: For every 1.0° less of DF-CLIN, there was a 1.0° decrease in hip flexion excursion (r2 = 0.21, P = 0.05), 1.2° decrease in peak knee flexion angles (r2 = 0.37, P = 0.01), 0.9° decrease in knee flexion excursion (r2 = 0.40, P = 0.004), 0.002 N·m·N-1·cm-1 decrease in hip extensor work (r2 = 0.28, P = 0.02), and 0.001 N·m·N-1·cm-1 decrease in knee extensor work (r2 = 0.21, P = 0.05). For every 10% less of DF-%USED, there was a 3.2° increase in peak knee abduction angles (r2 = 0.26, P = 0.03) and 0.01 N·m·N-1·cm-1 lesser knee extensor work (r2 = 0.25, P = 0.03). CONCLUSION: Lower levels of both ankle DFROM and DF-%USED are associated with biomechanics that are considered to be associated with a higher risk of sustaining injury. CLINICAL RELEVANCE: While total ankle DFROM can predict some aberrant movement patterns, underutilization of available ankle DFROM can also lead to higher risk movement strategies. In addition to joint specific mobility training, clinicians should incorporate biomechanical interventions and technique feedback to promote the utilization of available motion.

Quadriceps muscle volume positively contributes to ACL volume.

Females have smaller anterior cruciate ligaments (ACLs) than males and smaller ACLs have been associated with a greater risk of ACL injury. Overall body dimensions do not adequately explain these sex differences. This study examined the extent to which quadriceps muscle volume (VOLQUAD ) positively predicts ACL volume (VOLACL ) once sex and other body dimensions were accounted for. Physically active males (N = 10) and females (N = 10) were measured for height, weight, and body mass index (BMI). Three-Tesla magnetic resonance images of their dominant and nondominant thigh and knee were then obtained to measure VOLACL , quadriceps, and hamstring muscle volumes, femoral notch width, and femoral notch width index. Separate three-step regressions estimated associations between VOLQUAD and VOLACL (third step), after controlling for sex (first step) and one body dimension (second step). When controlling for sex and sex plus BMI, VOLHAM , notch width, or notch width index, VOLQUAD consistently exhibited a positive association with VOLACL in the dominant leg, nondominant leg, and leg-averaged models (p < 0.05). Findings were inconsistent when controlling for sex and height (p = 0.038-0.102). Once VOLQUAD was included, only notch width and notch width index retained a statistically significant individual association with VOLACL (p < 0.01). Statement of Clinical Significance: The positive association between VOLQUAD and VOLACL suggests ACL size may in part be modifiable. Future studies are needed to determine the extent to which an appropriate training stimulus (focused on optimizing overall lower extremity muscle mass development) can positively impact ACL size and structure in young females.

Sex-Specific Changes in Physical Risk Factors for Anterior Cruciate Ligament Injury by Chronological Age and Stages of Growth and Maturation From 8 to 18 Years of Age.

OBJECTIVE: To critically assess the literature focused on sex-specific trajectories in physical characteristics associated with anterior cruciate ligament (ACL) injury risk by age and maturational stage. DATA SOURCES: PubMed, CINAHL, Scopus, and SPORTDiscus databases were searched through December 2021. STUDY SELECTION: Longitudinal and cross-sectional studies of healthy 8- to 18-year-olds, stratified by sex and age or maturation on ≥1 measure of body composition, lower extremity strength, ACL size, joint laxity, knee-joint geometry, lower extremity alignment, balance, or lower extremity biomechanics were included. DATA EXTRACTION: Extracted data included study design, participant characteristics, maturational metrics, and outcome measures. We used random-effects meta-analyses to examine sex differences in trajectory over time. For each variable, standardized differences in means between sexes were calculated. DATA SYNTHESIS: The search yielded 216 primary and 22 secondary articles. Less fat-free mass, leg strength, and power and greater general joint laxity were evident in girls by 8 to 10 years of age and Tanner stage I. Sex differences in body composition, strength, power, general joint laxity, and balance were more evident by 11 to 13 years of age and when transitioning from the prepubertal to pubertal stages. Sex differences in ACL size (smaller in girls), anterior knee laxity and tibiofemoral angle (greater in girls), and higher-risk biomechanics (in girls) were observed at later ages and when transitioning from the pubertal to postpubertal stages. Inconsistent study designs and data reporting limited the number of included studies. CONCLUSIONS: Critical gaps remain in our knowledge and highlight the need to improve our understanding of the relative timing and tempo of ACL risk factor development.

Relationship of Anterior Cruciate Ligament Volume and T2* Relaxation Time to Anterior Knee Laxity.

BACKGROUND: High anterior knee laxity (AKL) has been prospectively identified as a risk factor for anterior cruciate ligament (ACL) injuries. Given that ACL morphometry and structural composition have the potential to influence ligamentous strength, understanding how these factors are associated with greater AKL is warranted. HYPOTHESIS: Smaller ACL volumes combined with longer T2* relaxation times would collectively predict greater AKL. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: College-aged active male (n = 20) and female (n = 30) participants underwent magnetic resonance imaging (MRI) and AKL testing. T2-weighted MRI scans were used to assess ACL volumes, and T2* relaxation times were used to assess ACL structural composition. AKL was measured via a commercial knee arthrometer. Forward stepwise linear regression with sex and weight (first step; suppressor variables) as well as ACL volume and T2* relaxation time (second step; independent variables) was used to predict AKL (dependent variable). RESULTS: After initially adjusting for sex and weight (R 2 = 0.19; P = .006), smaller ACL volumes combined with longer T2* relaxation times collectively predicted greater AKL (R 2 = 0.52; P < .001; R 2 Δ = 0.32; P Δ < .001). A smaller ACL volume was the primary predictor of greater AKL (R 2 Δ = 0.28; P < .001), with a longer T2* relaxation time trending toward a significant contribution to greater AKL (R 2 Δ = 0.04; P = .062). After adjusting for ACL volume and T2* relaxation time, sex (partial r = 0.05; P = .735) and weight (partial r = 0.05; P = .725) were no longer significant predictors. CONCLUSION: AKL was largely predicted by ACL volume and to a lesser extent by T2* relaxation time (and not a person's sex and weight). These findings enhance our understanding of how AKL may be associated with a structurally weaker ACL. The current study presents initial evidence that AKL is a cost-effective and clinically accessible measure that shows us something about the structural composition of the ACL. As AKL has been consistently shown to be a risk factor for ACL injuries, work should be done to continue to investigate what AKL may tell a clinician about the structure and composition of the ACL.

The Effects of Gluteal Strength and Activation on the Relationship Between Femoral Alignment and Functional Valgus Collapse During a Single-Leg Landing.

CONTEXT: A bias toward femoral internal rotation is a potential precursor to functional valgus collapse. The gluteal muscles may play a critical role in mitigating these effects. OBJECTIVE: Determine the extent to which gluteal strength and activation mediate associations between femoral alignment measures and functional valgus collapse. DESIGN: Cross-sectional. SETTING: Research laboratory. PATIENTS OR OTHER PARTICIPANTS: Forty-five females (age = 20.1 [1.7] y; height = 165.2 [7.6] cm; weight = 68.6 [13.1] kg) and 45 males (age = 20.8 [2.0] y; height = 177.5 [8.7] cm; weight = 82.7 [16.5] kg), healthy for 6 months prior. INTERVENTION(S): Femoral alignment was measured prone. Hip-extension and abduction strength were obtained using a handheld dynamometer. Three-dimensional biomechanics and surface electromyography were obtained during single-leg forward landings. MAIN OUTCOME MEASURES: Forward stepwise multiple linear regressions determined the influence of femoral alignment on functional valgus collapse and the mediating effects of gluteus maximus and medius strength and activation. RESULTS: In females, less hip abduction strength predicted greater peak hip adduction angle (R2 change = .10; P = .02), and greater hip-extensor activation predicted greater peak knee internal rotation angle (R2 change = .14; P = .01). In males, lesser hip abduction strength predicted smaller peak knee abduction moment (R2 change = .11; P = .03), and the combination of lesser hip abduction peak torque and lesser gluteus medius activation predicted greater hip internal rotation angle (R2 change = .15; P = .04). No meaningful mediation effects were observed (υadj < .01). CONCLUSIONS: In females, after accounting for femoral alignment, less gluteal strength and higher muscle activation were marginally associated with valgus movement. In males, less gluteal strength was associated with a more varus posture. Gluteal strength did not mediate femoral alignment. Future research should determine the capability of females to use their strength efficiently.

A Magnetic Resonance Imaging-Compatible Device to Perform In Vivo Anterior Knee Joint Loading.

CONTEXT: Greater anterior knee laxity (AKL) is associated with impaired sensory input and decreased functional knee stability. As functional magnetic resonance imaging (MRI) is the gold standard for understanding brain function, methods to load the anterior cruciate ligament in the MRI environment could further our understanding of the ligament's sensory role in knee joint stability. OBJECTIVE: To design and validate an MRI-compatible anterior knee joint loading device. DESIGN: Descriptive laboratory study. SETTING: University laboratory study. PARTICIPANTS: Sixteen healthy and physically active females participated (age = 23.4 [3.7] y; mass = 64.4 [8.4] kg). INTERVENTIONS: The AKL was assessed by a commercially available arthrometer. The AKL was also assessed with a custom-made, MRI-compatible device that produced anterior knee joint loading in a manner similar to the commercial arthrometer while obtaining dynamic structural MRI data. MAIN OUTCOME MEASUREMENTS: The AKL (in millimeters) at 133 N of loading was assessed with the commercial knee arthrometer. Anterior displacement of the tibia relative to the femur obtained at 133 N of loading was measured from dynamic MRI data obtained during usage of the custom device. Pearson correlations were used to examine relationships between the 2 measures. The 95% limits of agreement compared the absolute differences between the 2 devices. RESULTS: There was a 3.2-mm systematic difference between AKL (6.3 [1.6] mm) and anterior tibial translation (3.2 [1.0] mm) measures. There was a significant positive correlation between values obtained from the commercial arthrometer and the MRI-compatible device values (r = .553, P = .026). CONCLUSIONS: While systematic differences were observed, the MRI-compatible anterior knee joint loading device anteriorly translated the tibia relative to the femur in a similar manner to a commercial arthrometer design to stress the anterior cruciate ligament. Such a device may be beneficial in future functional magnetic resonance imaging study of anterior cruciate ligament mechanoreception.

Sex-Specific Associations between Cartilage Structure and Metabolism at Rest and Acutely Following Walking and Drop-Landing.

OBJECTIVE: Cartilage health is thought to be dependent on the relationship between mechanics, structure, and metabolism, rather than these individual components in isolation. Due to sex differences in cartilage health, there is need to determine if the relationships between these cartilage components separately for males and females. Therefore, we sought to determine the sex-specific associations between cartilage structure and metabolism at rest and their acute response following walking and drop-landing in healthy individuals. DESIGN: A cartilage ultrasound assessment and an ante-cubital blood draw were performed before and after walking and drop-landing conditions in 20 males and 20 females. Cartilage structure was assessed via medial and lateral femoral cartilage cross-sectional area. Cartilage metabolism was quantified with serum cartilage oligomeric matrix protein (COMP) concentration. Percent change scores from pre- to postloading were used to calculate acute alterations in cross-sectional area and COMP. Correlational analyses were used to assess the association between cartilage structure and metabolism measures separately for males and females. RESULTS: In females, greater resting COMP concentration was associated with less cartilage cross-sectional area in the medial(ρ = -0.50, P = 0.03) and lateral (ρ = -0.69, P = 0.001) femur. Resting cartilage measures were not associated among males. Following walking and drop-landing, percent change scores in cartilage structure and metabolism were not associated. CONCLUSIONS: This study highlights that, in females, thinner anterior femoral cartilage is associated with greater resting serum COMP concentrations, a biomarker often linked to cartilage breakdown. Future studies into the relationships between various cartilage components should consider sex-specific analyses as these relationships are sex dependent.

ACL Size and Notch Width Between ACLR and Healthy Individuals: A Pilot Study.

BACKGROUND: Given the relatively high risk of contralateral anterior cruciate ligament (ACL) injury in patients with ACL reconstruction (ACLR), there is a need to understand intrinsic risk factors that may contribute to contralateral injury. HYPOTHESIS: The ACLR group would have smaller ACL volume and a narrower femoral notch width than healthy individuals after accounting for relevant anthropometrics. STUDY DESIGN: Cross-sectional study. LEVEL OF EVIDENCE: Level 3. METHODS: Magnetic resonance imaging data of the left knee were obtained from uninjured (N = 11) and unilateral ACL-reconstructed (N = 10) active, female, collegiate-level recreational athletes. ACL volume was obtained from T2-weighted images. Femoral notch width and notch width index were measured from T1-weighted images. Independent-samples t tests examined differences in all measures between healthy and ACLR participants. RESULTS: The ACLR group had a smaller notch width index (0.22 ± 0.02 vs 0.25 ± 0.01; P = 0.004; effect size, 1.41) and ACL volume (25.6 ± 4.0 vs 32.6 ± 8.2 mm3/(kg·m)-1; P = 0.025; effect size, 1.08) after normalizing by body size. CONCLUSION: Only after normalizing for relevant anthropometrics, the contralateral ACLR limb had smaller ACL size and narrower relative femoral notch size than healthy individuals. These findings suggest that risk factor studies of ACL size and femoral notch size should account for relevant body size when determining their association with contralateral ACL injury. CLINICAL RELEVANCE: The present study shows that the method of the identified intrinsic risk factors for contralateral ACL injury could be used in future clinical screening settings.

The Effects of Attentional Focus on Brain Function During a Gross Motor Task.

CONTEXT: Although the beneficial effects of using an external focus of attention are well documented in attainment and performance of movement execution, neural mechanisms underlying external focus' benefits are mostly unknown. OBJECTIVE: To assess brain function during a lower-extremity gross motor movement while manipulating an internal and external focus of attention. DESIGN: Cross-over study. SETTING: Neuroimaging center Participants: A total of 10 healthy subjects (5 males and 5 females) Intervention: Participants completed external and internal focus of attention unilateral left 45° knee extension/flexion movements at a rate of 1.2 Hz laying supine in a magnetic resonance imaging scanner for 4 blocks of 30 seconds interspersed with 30-second rest blocks. During the internal condition, participants were instructed to "squeeze their quadriceps." During the external condition, participants were instructed to "focus on a target" positioned above their tibia. MAIN OUTCOME MEASURES: T1 brain structural imaging was performed for registration of the functional data. For each condition, 3T functional magnetic resonance imaging blood oxygenation level dependent data representing 90 whole-brain volumes were acquired. RESULTS: During the external relative to internal condition, increased activation was detected in the right occipital pole, cuneal cortex, anterior portion of the lingual gyrus, and intracalcarine cortex (Zmax = 4.5-6.2, P < .001). During the internal relative to external condition, increased activation was detected in the left primary motor cortex, left supplementary motor cortex, and cerebellum (Zmax = 3.4-3.5, P < .001). CONCLUSIONS: Current results suggest that an external focus directed toward a visual target produces more brain activity in regions associated with vision and ventral streaming pathways, whereas an internal focus manipulated through instruction increases activation in brain regions that are responsible for motor control. Results from this study serve as baseline information for future prevention and rehabilitation investigations of how manipulating focus of attention can constructively affect neuroplasticity during training and rehabilitation.

Temporal kinematic differences throughout single and double-leg forward landings.

Screening methods for anterior cruciate ligament (ACL) injuries often involve double-leg landings, though the majority of ACL injuries occur during single-leg landings. Differences in kinematic temporal characteristics between single-leg and double-leg landings are poorly understood. The purpose of this study was to examine discrete and temporal kinematics associated with functional valgus collapse during single-leg and double-leg landings (LANDSL and LANDDL). Three-dimensional kinematics were obtained during the landing phases of LANDSL and LANDDL in ninety participants (45 females: 20.1 ± 1.7 yr, 165.2 ± 7.6 cm, 68.6 ± 13.1 kg; 45 males: 20.7 ± 2.0 yr, 177.7 ± 8.5 cm, 82.8 ± 16.3 kg). Peak joint angles and time series curves for frontal and transverse plane hip and knee kinematics were analyzed with an RMANOVA (discrete variables) and Statistical Parametric Mapping (SPM) paired t-tests (time series). LANDSL elicited greater knee abduction than LANDDL from 0 to 35% (0-73 ms) but greater knee adduction from 54 to 100% (112-207 ms). Peak knee abduction was 2.0° greater during LANDDL than during LANDSL (p < .001). LANDSL elicited greater hip adduction than LANDDL from 2 to 33% (4-69 ms) and greater hip abduction from 49 to 100% (102-207 ms). Peak hip adduction was 4.6° greater during LANDSL than during LANDDL (p < .001). LANDSL elicited less knee internal rotation from 0 to 3% and greater hip internal rotation from 52 to 75% of the landing phase. Peak transverse plane joint angles did not differ between tasks. During the time frame in which ACL injuries are thought to occur, LANDSL elicited frontal plane knee and hip movement consistent with risky biomechanics. Researchers and clinicians should be cognizant of how a chosen screening task alters observed kinematic effects.

The Influence of Hip Structure on Functional Valgus Collapse During a Single-Leg Forward Landing in Females.

Clinical femoral anteversion (Craig test) and hip range of motion (ROM) have been associated with valgus collapse, but their clinical usefulness in predicting biomechanics is unknown. Our purpose was to determine the individual and combined predictive power of femoral anteversion and passive hip ROM on 3-dimensional valgus collapse (hip internal rotation and adduction, knee rotation, and abduction) during a single-leg forward landing in females. Femoral anteversion and passive hip ROM were measured on 20 females (24.9 [4.1] y, 168.7 [8.0] cm, 63.8 [11.6] kg). Three-dimensional kinematics and kinetics were collected over 5 trials of the task. Each variable was averaged across trials. Backward, stepwise regressions determined the extent to which our independent variables were associated with valgus collapse. The combination of greater hip internal and external rotation ROM (partial r = .52 and .56) predicted greater peak knee internal rotation moment (R2 = .38, P = .02). Less hip internal rotation ROM (partial r = -.44) predicted greater peak knee abduction moments (R2 = .20, P = .05). Greater total hip ROM (internal and external rotation ROM) was not consistently associated with combined motions of valgus collapse but was indicative of isolated knee moments. Passive hip ROM is more associated with knee moments than is femoral anteversion as measured with Craig test.

Sex Comparisons of In Vivo Anterior Cruciate Ligament Morphometry.

CONTEXT: Females have consistently higher anterior cruciate ligament (ACL) injury rates than males. The reasons for this disparity are not fully understood. Whereas ACL morphometric characteristics are associated with injury risk and females have a smaller absolute ACL size, comprehensive sex comparisons that adequately account for sex differences in body mass index (BMI) have been limited. OBJECTIVE: To investigate sex differences among in vivo ACL morphometric measures before and after controlling for femoral notch width and BMI. DESIGN: Cross-sectional study. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: Twenty recreationally active men (age = 23.2 ± 2.9 years, height = 180.4 ± 6.7 cm, mass = 84.0 ± 10.9 kg) and 20 recreationally active women (age = 21.3 ± 2.3 years, height = 166.9 ± 7.7 cm, mass = 61.9 ± 7.2 kg) participated. MAIN OUTCOME MEASURE(S): Structural magnetic resonance imaging sequences were performed on the left knee. Anterior cruciate ligament volume, width, and cross-sectional area measures were obtained from T2-weighted images and normalized to femoral notch width and BMI. Femoral notch width was measured from T1-weighted images. We used independent-samples t tests to examine sex differences in absolute and normalized measures. RESULTS: Men had greater absolute ACL volume (1712.2 ± 356.3 versus 1200.1 ± 337.8 mm3; t38 = -4.67, P < .001) and ACL width (8.5 ± 2.3 versus 7.0 ± 1.2 mm; t38 = -2.53, P = .02) than women. The ACL volume remained greater in men than in women after controlling for femoral notch width (89.31 ± 15.63 versus 72.42 ± 16.82 mm3/mm; t38 = -3.29, P = .002) and BMI (67.13 ± 15.40 versus 54.69 ± 16.39 mm3/kg/m2; t38 = -2.47, P = .02). CONCLUSIONS: Whereas men had greater ACL volume and width than women, only ACL volume remained different when we accounted for femoral notch width and BMI. This suggests that ACL volume may be an appropriate measure of ACL anatomy in investigations of ACL morphometry and ACL injury risk that include sex comparisons.

Potential Mediators of Load-Related Changes in Movement Complexity in Young, Healthy Adults.

CONTEXT: Movement screening has become increasingly popular among tactical professionals. This popularity has motivated the design of interventions that cater to improving outcomes on the screens themselves, which are often scored in reference to an objective norm. In contrast to the assumptions underlying this approach, dynamical systems theory suggests that movements arise as a function of continuously evolving constraints and that optimal movement strategies may not exist. To date, few data address behavioral complexity in the fundamental movement tasks commonly used in clinical screenings. OBJECTIVE: To provide evidence of complex variability during movement screens and test the role of modifiable-that is, trainable-constraints in mediating loss of complexity during experimental-task manipulations. DESIGN: Crossover study. SETTING: Research laboratory. PATIENTS OR OTHER PARTICIPANTS: Twenty-five male (age = 23.96 ± 3.74 years, height = 178.82 ± 7.51 cm, mass = 79.66 ± 12.66 kg) and 25 female (age = 22.00 ± 2.02 years, height = 165.40 ± 10.24 cm, mass = 63.98 ± 11.07 kg) recreationally active adults. INTERVENTION(S): Participants performed tests of balance, range of motion, and strength. Additionally, they performed cyclical movement tasks under a control (C) condition and while wearing an 18.10-kg weight vest (W). MAIN OUTCOME MEASURE(S): Ground reaction forces were sampled at 1000 Hz and used to calculate center of pressure during cyclical movement tests. Multivariate multiscale entropy (MMSE) for the center-of-pressure signal was then calculated. Condition effects (C versus W) were analyzed using paired t tests, and penalized varying-coefficients regression was used to identify models predicting entropy outcomes from balance, range of motion, and strength. RESULTS: The MMSE decreased during the W condition (MMSEC > MMSEW; t49 range = 3.17-5.21; all P values < .01). CONCLUSIONS: Moderate evidence supported an association between modifiable constraints and behavioral complexity, but a role in mediating load-related loss of complexity was not demonstrated.