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Comput Biol Med ; 81: 24-31, 2017 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-28011418

RESUMO

This paper describes a novel temporal logic-based framework for reasoning with continuous data collected from wearable sensors. The work is motivated by the Metabolic Syndrome, a cluster of conditions which are linked to obesity and unhealthy lifestyle. We assume that, by interpreting the physiological parameters of continuous monitoring, we can identify which patients have a higher risk of Metabolic Syndrome. We define temporal patterns for reasoning with continuous data and specify the coordination mechanisms for combining different sets of clinical guidelines that relate to this condition. The proposed solution is tested with data provided by twenty subjects, which used sensors for four days of continuous monitoring. The results are compared to the gold standard. The novelty of the framework stands in extending a temporal logic formalism, namely the Event Calculus, with temporal patterns. These patterns are helpful to specify the rules for reasoning with continuous data and in combining new knowledge into one consistent outcome that is tailored to the patient's profile. The overall approach opens new possibilities for delivering patient-tailored interventions and educational material before the patients present the symptoms of the disease.


Assuntos
Diagnóstico por Computador/métodos , Diagnóstico por Computador/normas , Aprendizado de Máquina , Síndrome Metabólica/diagnóstico , Monitorização Ambulatorial/métodos , Monitorização Ambulatorial/normas , Reconhecimento Automatizado de Padrão/métodos , Algoritmos , Diagnóstico por Computador/instrumentação , Europa (Continente) , Humanos , Monitorização Ambulatorial/instrumentação , Reconhecimento Automatizado de Padrão/normas , Guias de Prática Clínica como Assunto , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
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