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Ultrasonics ; 67: 136-150, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26836291

RESUMO

We investigate the potential of using ultrasonic diffraction tomography technique for characterization of biological tissues. Unlike most of other studies where ultrasonic tomography operates at frequencies higher than 1 MHz, low-frequency tomography uses lower frequencies on the order of 0.3-0.5 MHz. Such a choice is due to low attenuation at these frequencies, resulting in higher precision of input data. In this paper we explore transmission and reflection schemes for both 2D (layer-by-layer) and 3D tomography. We treat inverse tomography problems as coefficient inverse problems for the wave equation. The time-domain algorithms employed for solving the inverse problem of low-frequency tomography focus on the use of GPU clusters. The results obtained show that a spatial resolution of about 2-3mm can be achieved when operating at the wavelength of about 5mm even using a stationary 3D scheme with a few fixed sources and no rotating elements. The study primarily focuses on determining the performance limits of ultrasonic tomography devices currently designed for breast cancer diagnosis.


Assuntos
Neoplasias da Mama/diagnóstico por imagem , Simulação por Computador , Neoplasias de Tecidos Moles/diagnóstico por imagem , Ultrassonografia/métodos , Algoritmos , Humanos , Tomografia por Raios X
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