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Introduction: Re-establishment of coronary artery blood flow in diabetic patients has always been a controversial issue in the treatment of cardiovascular diseases. Due to the importance of this issue and the increase in mortality due to heart disease, the present study was performed to determine the relationship between HbA1C and cardiovascular events in diabetic patients with coronary angioplasty referred to Imam Khomeini Hospital in Ahvaz. Methods: This was a descriptive cross-sectional study in which 114 patients were enrolled in a census study that was followed for 3 to 6 months. Data was collected by a checklist and by the researcher using the patient's medical record. Then it was analyzed by SPSS 22 software and descriptive statistics. Results: There was no significant relationship between age, gender, family history of diabetes, family history of heart disease, duration of diabetes, stroke, myocardial infarction, and heart failure with HbA1c (P > 0.05). However, there was a significant relationship between the type of coronary angioplasty, hypertension, and heart block with HbA1c (P < 0.05). Conclusion: According to the results of this study, there was a significant relationship between the type of coronary angioplasty, hypertension, and heart block with HbA1c; thus HbA1c should be better controlled in diabetic patients who decide to have angioplasty.
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OBJECTIVE: This study defines the relationship between salivary beta-2 microglobulin (ß2-M) and intensity of uremia in male patients diagnosed with chronic renal failure (CRF). MATERIALS AND METHODS: In total of 42 males were enrolled in a case-control study. There were 21 cases of CRF and 21 control cases. We collected 10cc of saliva plus 5 cc of blood from all patients to determine ß2-M, blood urea nitrogen (BUN) and creatinine (Cr) levels. RESULTS: There was a correlation between the level of serum BUN and salivary urea in controls and patients, which was statistically significant for controls (p=0.028).The correlation between serum and salivary Cr was 0.195 in controls (p=0.398) and 0.598 in patients (p=0.006), which was statistically significant in patients. The correlation between serum and saliva was 0.133 (p=0.566) in controls and 0.078 (p=0.737) in patients, which was not statistically significant. The correlation between serum BUN and ß2-M was 0.168 (p=0.469) in the control group and 0.629 (p=0.002) in patients, which was statistically significant in patients. The correlation between serum Cr and ß2-M was 0.110 (p=0.635) in the control group and 0.678 (p=0.001) in patients, which was statistically significant in patients. The correlation between serum BUN and salivary ß2-M was 0.093 (p=0.0690) in controls and 0.152 (p=0.152) in patients, which was not statistically significant. The correlation between serum Cr and salivary ß2-M was 0.072 (p=0.070) in the control group and 0.286 (p=0.209) in patients, which was not statistically significant in either group. CONCLUSION: The results of the study indicated that salivary ß2-M cannot be used as a noninvasive indicator to detect the severity of renal failure.
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BACKGROUND: This randomized study was aimed to compare the diagnostic value of two head-up tilt testing protocols using sublingual nitroglycerin for provocation in patients with recurrent unexplained syncope and normal heart. METHODS: The patients with normal findings in physical examination, electrocardiography and echocardiography were randomly submitted to one of upright tilt test protocols. The only difference between two protocols was that nitroglycerin was administered after a five minute resting phase in supine position during protocol B. We also considered eighty normal persons as the control group. RESULTS: Out of 290 patients that underwent tilt testing, 132 patients were in group A versus 158 patients in group B. Both groups had an identical distribution of clinical characteristics. Tilt test was positive in 79 patients in group A (25 in passive phase, 54 in active phase) versus 96 patients in group B (43 in passive phase, 53 in active phase). There was no significant difference between results in two groups (P value= 0.127). Forty cases were tested with protocol A and forty underwent tilt testing with protocol B. Tilt test was positive in 4 cases with protocol A versus 3 cases in protocol B. The positive rates of tilt testing with protocol A was 60% while it was 61% in protocol B. The specificity of testing with protocol A was 90% and it was 92.5% in protocol B. CONCLUSIONS: According to our data, adding a period of rest and returning to supine position before nitroglycerin administration had no additional diagnostic yield.