RESUMO
We studied morphological changes in rat abdominal aorta and vena cava inferior induced by endovascular microwave destruction. This treatment induced thrombosis and necrosis of the vascular walls, but fibrous framework was not completely destroyed. Then we observed irreversible changes in vessels: obliteration, atrophy of the aorta walls, and sclerosis of venous walls. The preserved fibrous framework of the vessel walls probably plays a role of a framework for the formation of fibrous tissue.
Assuntos
Aorta Abdominal/patologia , Aorta Abdominal/efeitos da radiação , Endotélio Vascular/efeitos da radiação , Micro-Ondas , Veia Cava Inferior/patologia , Veia Cava Inferior/efeitos da radiação , Animais , Aorta Abdominal/ultraestrutura , Endotélio Vascular/patologia , Endotélio Vascular/ultraestrutura , Microscopia Eletrônica de Varredura , Necrose , Ratos , Veia Cava Inferior/ultraestruturaRESUMO
We studied morphological changes in the liver after local MW-destruction. Microwave radiation damaged vascular walls with the formation of extensive necrotic focus; demarcation zone appeared 24 h after exposure, encapsulation occurred after 7 days, and replacement with a fine cicatrix formed by mature connective tissue after 4 months.
Assuntos
Fígado/efeitos da radiação , Micro-Ondas/efeitos adversos , Animais , Fígado/patologia , Masculino , Ratos , Ratos Wistar , Fatores de TempoAssuntos
Criocirurgia/normas , Hemangioma/cirurgia , Pré-Escolar , Criocirurgia/métodos , Hemangioma/terapia , Humanos , Lactente , Ondas de RádioRESUMO
The mechanical parameters of the skin and scarring tissues were assessed in children aged 3-14 years who had various scar types, by using an ACA apparatus, which measures the propagation rates of superficial acoustic waves in the skin. It was found that the types (atrophic, hypertrophic, keloid) of scars could be significantly differentiated from the value of this parameter. The comparison of clinical and acoustic data shows high (as high as 90%) significance of the latter.
Assuntos
Acústica , Cicatriz/patologia , Adolescente , Atrofia , Criança , Pré-Escolar , Cicatriz Hipertrófica/patologia , Diagnóstico Diferencial , Humanos , Queloide/patologia , Pele/patologiaRESUMO
The procedures associated with the application of a super-frequency electromagnetic field (SFEMF) are being introduced into a therapeutical process in their various modifications at the Pediatric Surgery Hospital of Russian State Medical University. This has been preceded by enormous experimental work aimed at evaluating the potentialities of SFEMF for potentiation of cryogenic exposure and for individual use for endovascular occlusion and local hyperthermia. A total of 947 patients were treated with SFEMF from 1979 to 1990. The largest group included children with hemangiomas of various site (n = 465) and those with cheloid scars (n = 395). Thirty-one patients underwent intravascular coagulation with SFEMF in the treatment of arterial and venous malformations and 31 patients were treated for pigmentary spots of various site with SFEMF + cryodestruction. Local hypothermia was performed in 25 children with extensive hemangiomas of the face and neck with SFEMF. The total therapeutical benefits reached 98%. For these purposes the authors used a Plot routine apparatus, 915 mHz, with a set of contact and special emitters. The experience with SFEMF in pediatric surgery suggests that it is highly effective and the trend is promising.
Assuntos
Criocirurgia , Hemangioma/terapia , Hipertermia Induzida , Hipotermia Induzida , Queloide/terapia , Fotocoagulação a Laser , Animais , Pré-Escolar , Terapia Combinada , Campos Eletromagnéticos , Humanos , Lactente , Radiação , Resultado do TratamentoRESUMO
It has been established that heat conductivity was markedly increased after UHF-irradiation. The combined use of UHF-irradiation and cryogenic destruction is 30-40 times as effective as cryogenic destruction alone.
Assuntos
Temperatura Alta , Fígado/efeitos da radiação , Micro-Ondas , Animais , Terapia Combinada , Criocirurgia , Fígado/fisiologia , CoelhosAssuntos
Embolização Terapêutica , Hemangioma/terapia , Neoplasias Cutâneas/terapia , Varicocele/terapia , Adolescente , Criança , Pré-Escolar , Humanos , Lactente , MasculinoAssuntos
Criocirurgia , Neoplasias Experimentais/cirurgia , Animais , Criocirurgia/métodos , Estudos de Avaliação como Assunto , Cinética , Camundongos , Camundongos Endogâmicos C57BL , Camundongos Endogâmicos CBA , Transplante de Neoplasias , Neoplasias Experimentais/mortalidade , Neoplasias Experimentais/patologiaAssuntos
Hepatite Crônica/sangue , Lipídeos/sangue , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeAssuntos
Queloide/terapia , Adolescente , Adulto , Criança , Pré-Escolar , Terapia Combinada , Criocirurgia , Humanos , Micro-Ondas/uso terapêuticoAssuntos
Criocirurgia/tendências , Pediatria/tendências , Animais , Criança , Criocirurgia/instrumentação , Cães , Cobaias , Humanos , Magnetoterapia , Matemática , Modelos Biológicos , Coelhos , Temperatura , Condutividade TérmicaRESUMO
Experience gained so far by cryogenic surgery indicates that the possibilities of cryodestruction of sizable pathological formations are fairly limited. To overcome this barrier, it is necessary to change the status of the tissues, making them more sensitive to cryodestruction. The theoretical investigations suggest that microwave irradiation is one of the factors capable to change the status of tissues and to raise their sensitivity to cold exposure. Experiments made on the liver and muscles from rabbits, dogs and guinea-pigs have demonstrated that preliminary microwave irradiation followed by local freezing promotes the death of tissues 4-6-fold as compared to control.