FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis.

BACKGROUND: Chronic Gulf War Illness (GWI) is characterized by cognitive and mood impairments, as well as persistent neuroinflammation and oxidative stress. This study aimed to investigate the efficacy of Epidiolex®, a Food and Drug Administration (FDA)-approved cannabidiol (CBD), in improving brain function in a rat model of chronic GWI. METHODS: Six months after exposure to low doses of GWI-related chemicals [pyridostigmine bromide, N,N-diethyl-meta-toluamide (DEET), and permethrin (PER)] along with moderate stress, rats with chronic GWI were administered either vehicle (VEH) or CBD (20 mg/kg, oral) for 16 weeks. Neurobehavioral tests were conducted on 11 weeks after treatment initiation to evaluate the performance of rats in tasks related to associative recognition memory, object location memory, pattern separation, and sucrose preference. The effect of CBD on hyperalgesia was also examined. The brain tissues were processed for immunohistochemical and molecular studies following behavioral tests. RESULTS: GWI rats treated with VEH exhibited impairments in all cognitive tasks and anhedonia, whereas CBD-treated GWI rats showed improvements in all cognitive tasks and no anhedonia. Additionally, CBD treatment alleviated hyperalgesia in GWI rats. Analysis of hippocampal tissues from VEH-treated rats revealed astrocyte hypertrophy and increased percentages of activated microglia presenting NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) complexes as well as elevated levels of proteins involved in NLRP3 inflammasome activation and Janus kinase/signal transducers and activators of the transcription (JAK/STAT) signaling. Furthermore, there were increased concentrations of proinflammatory and oxidative stress markers along with decreased neurogenesis. In contrast, the hippocampus from CBD-treated GWI rats displayed reduced levels of proteins mediating the activation of NLRP3 inflammasomes and JAK/STAT signaling, normalized concentrations of proinflammatory cytokines and oxidative stress markers, and improved neurogenesis. Notably, CBD treatment did not alter the concentration of endogenous cannabinoid anandamide in the hippocampus. CONCLUSIONS: The use of an FDA-approved CBD (Epidiolex®) has been shown to effectively alleviate cognitive and mood impairments as well as hyperalgesia associated with chronic GWI. Importantly, the improvements observed in rats with chronic GWI in this study were attributed to the ability of CBD to significantly suppress signaling pathways that perpetuate chronic neuroinflammation.

Prosthetic Management of an Eviscerated Eye of a 13-month-old Patient: A Case Report.

Background: On account of loss of eye following Rubella infection, a 13-month-old baby girl patient required a maxillofacial prosthesis to restore her facial esthetics and social health as she grows. Case presentation: The process of prosthesis fabrication began at the time of enucleation where a conformer was given. Post healing the procedure was completed in a span of 2 days taking adequate trials and cross references for the like-like appearance of the prosthesis. Conclusion: A heat-cure acrylic resin based prosthetic eye was delivered with adequate instructions on the insertion and removal and hygiene maintenance given to the care providers. How to cite this article: Shetty NHG, Shetty MS, Saha S, et al. Prosthetic Management of an Eviscerated Eye of a 13-month-old Patient: A Case Report. Int J Clin Pediatr Dent 2024;17(1):89-91.

Correlation of "K" plane to occlusal plane and three different ala-tragal lines in dentulous subjects with different skeletal forms: A cephalometric study.

Aim: Orientation of the occlusal plane is an important clinical procedure for complete denture fabrication. An attempt had been made to reconstruct the occlusal plane using a different reference plane. The aim of this study was to find the correlation of the "K" plane to the occlusal plane and to assess the angular deviation between the K-plane to the occlusal plane (KO) with different skeletal forms. Settings and Design: An in vivo observational study was conducted on dentulous subjects having Class I dental occlusion with different skeletal forms undergoing orthodontic treatment. Materials and Methods: The study was conducted on 54 subjects aged 18-30 years. Metallic balls (3 mm in diameter) were attached to the desired landmarks, and a lateral cephalogram was taken for each subject. Cephalometric analysis was done using the Dolphin Imaging software, and the values obtained were recorded and subjected to statistical analysis. Statistical Analysis Used: The values obtained were recorded and subjected to statistical analysis using simple descriptive analysis, Shapiro-Wilk test, Mann-Whitney U-test, and Pearson's correlation. Results: A positive correlation was found between KO with a mean angular deviation of 8.59° ± 3.05°. The angle was found to be steeper in skeletal Class II subjects. Conclusions: Clinical application of the K-plane to use as a reference plane to orient the posterior occlusal plane can enhance the treatment outcome for a removable prosthesis. The results of this study provide a theoretical foundation for the practical restoration of the occlusal plane in different skeletal forms.

Evaluation of the marginal fit of full contoured zirconia, lithium disilicate and metal crowns fabricated using CAD-CAM: An in vitro study.

Introduction: The marginal fit of any dental restoration is vital to its long-term success. Lack of adequate fit is potentially detrimental to both the tooth and the supporting periodontal tissues. The purpose of this study was to evaluate the marginal fit of monolithic zirconia, monolithic lithium disilicate and monolithic metal crowns and compare the three groups. Methods: The study was conducted by fabricating ten samples for each group, total of 30 samples. A premolar stainless steel die was used to standardize the preparation. PVS putty material was used to make impressions of the model and was poured using type IV die stone. The samples were all fabricated using CAD-CAM. The marginal gap was measured by SEM, and the results were analysed using SPSS software. Results: The mean marginal gap of zirconia, metal and lithium disilicate crowns was 79.49 µm, 46.83 µm and 70.79 µm, respectively. Discussion: The metal group showed the lowest marginal gap among the groups. This difference in marginal fit is due to the sintering process where the organic binders in soft metal burn out and the metallic powder particles are being sintered (caked) without creating a fused phase. Clinical Significance: Marginal fit plays a very important role in the long-term success of a crown. Discrepancy in marginal fit results in food and plaque accumulation causing caries and periodontal breakdown, eventuating the failure of the restoration. A perfect marginal fit would enhance the longevity of any indirect restoration. Knowledge about which indirect restoration has the best marginal fit is critical.

Correlation of intercondylar distance and occlusal vertical dimension in dentate individuals: A clinical study.

STATEMENT OF PROBLEM: Determining the vertical dimension of occlusion for an edentulous patient depends on clinical judgment and the skill and experience of the dentist. Though many methods have been advocated, a universally accepted method of determining the vertical dimension of occlusion in edentulous patients is lacking. PURPOSE: This clinical study aimed to find a correlation between the intercondylar distance and occlusal vertical dimension in dentate individuals. MATERIAL AND METHODS: This study was conducted on 258 dentate individuals aged 18 to 30 years. The Denar posterior reference point was used to determine the center of the condyle. The posterior reference point was marked on either side of the face with this scale, and the intercondylar width between these 2 posterior reference points was measured with custom digital vernier calipers. A modified Willis gauge was used to measure the occlusal vertical dimension from the base of the nose to the lower border of the chin when the teeth were in maximum intercuspation. The relationship between the ICD and OVD was analyzed with the Pearson correlation test. Simple regression analysis was used to formulate a regression equation. RESULTS: The mean intercondylar distance was 133.5 mm, and the mean occlusal vertical dimension was 55.4 mm. A statistically significant correlation (R=0.619) was found between the intercondylar distance and occlusal vertical dimension in the study population (P<.001). CONCLUSIONS: A significant correlation was found between the intercondylar distance and occlusal vertical dimension of the participants. Occlusal vertical dimension may be predicted from the intercondylar distance by using a regression model.

An Assessment of the Accuracy of Recurring Esthetic Dental Proportion: An In Vivo Comparative Analysis of Maxillary Anterior Teeth Proportion With Chu's Gauge and Custom-Made Calipers.

Smile designing, in harmony with nature, has always been a challenge in dentistry. Several theories have been proposed in the past with a view to replicate an esthetic smile. One such method proposed by Dr. Chu involves using the recurring esthetic dental (RED) proportion. He designed a scale for calculating the average values for the height and width of upper anterior teeth for a specified population. However, whether this average is valid for other populations has not been verified. Hence, this study was conducted to evaluate if Chu's gauge value agrees with the dimension of anterior teeth in the South Indian population. The study involved 362 subjects whose anterior teeth dimension was assessed using Chu's gauge and a custom-made caliper. The proportion of the population whose dimension aligns with the average values on Chu's gauge was evaluated. The results showed that in the cohort, 39% had their central incisor dimension coinciding with the red band of Chu's esthetic scale, 10% had their lateral incisor coinciding with the blue band of Chu's esthetic scale, and 6.4% of the subjects had their canine dimension coinciding with the yellow band of Chu's esthetic scale.

An Evaluation of the Relation Between Variation in Arch Forms and Relative Parallelism of the Occlusal Plane to the Line Joining the Inferior Border of Ala of the Nose With Different Tragal Levels of the Ear in Dentulous Subjects: An In Vivo Study.

Introduction The purpose of this study was to evaluate which of the three positions on the tragus (superior, middle, and inferior), when connected to the inferior border of the ala of the nose, was the most parallel to the natural occlusal plane in dentate patients, to correlate the level of the naturally existing occlusal plane with the ala-tragal line when the tragus was divided into three portions (superior, middle, and inferior), and to determine which position in the tragus occlusal plane is the most parallel. The study also evaluated the correlation between the variation of arch forms and the relative parallelism of the occlusal plane to the ala-tragal line at different tragal levels. Methods This study included 1405 subjects between the ages of 18 and 35 years. A custom-made occlusal plane analyzer was used to check the relative parallelism between the existing occlusal plane and the ala-tragal line when the tragus was divided into the superior, middle, and inferior portions. The Fox plane of the occlusal plane analyzer was placed on the occlusal plane and the paralleling rod was adjusted till parallelism was obtained. The point on the tragus (superior, middle, or inferior) at which parallelism existed was recorded. The study also measured the inter-canine and intermolar distance to find the type of arch form and related it to the position (superior, middle, or inferior) at which the ala tragal line was parallel to the occlusal plane. The assessment was done on both the right and left sides of the subjects. Results Out of the 2810 tragi, the most common location at which parallelism was established was the inferior part of the tragus, which accounted for 47% of the total. Seventy-one percent (71%) of the subjects showed ovoid arch form. When the variation of arch forms was compared to the level of occlusal plane, 46.8% of the subjects with tapered arch form, 54.5% of subjects with square arch form, and 46.0% of subjects with ovoid arch form had the level of the occlusal plane at the inferior portion of the tragus. Conclusion The result of the study indicated that in the majority of the tragi studied, 47% of the subjects had the occlusal plane parallel to a line joining the inferior border of the ala of the nose to the inferior part of the tragus. Irrespective of the arch form, the occlusal plane was found parallel to a line joining the inferior border of the ala of the nose and the inferior part of the tragus. Thus the tragal position did not show any correlation to the variation of arch forms.

Prosthodontic Management of Congenital Hypothyroidism with Anodontia: A Case Report.

Thyroid dysfunction has various manifestations which include orofacial abnormalities like delayed eruption, retained deciduous teeth, etc. Early detection of this deregulation of thyroid homeostasis can prevent associated complications. This report is a case of congenital hypothyroidism (CH) in a 4-year-old boy who presented with a completely edentulous maxilla and hypodontic mandible. Based on various biochemical and radiographic investigations, a diagnosis of CH was established. He was prosthodontically rehabilitated with removable dentures. How to cite this article: Bhat V, Bhat VS, Vadakkan J, et al. Prosthodontic Management of Congenital Hypothyroidism with Anodontia: A Case Report. Int J Clin Pediatr Dent 2021;14(4):586-589.

Influence of Aerated Drink, Mouthwash, and Simulated Gastric Acid on the Surface Roughness of Dental Ceramics: A Comparative In Vitro Study.

BACKGROUND: Dental ceramics are known for their natural appearance and their durable chemical and optical properties, and their uses mainly reflect their excellent aesthetic properties, biocompatibility and resistance to wear. In addition, dental ceramics are considered to be chemically inert restorative material with large differences in the chemical compositions and microstructures. Although ceramics exhibit excellent physical properties and biocompatibility, the oral environment presents a series of external factors that affect its physical and mechanical properties in its long term function. AIMS AND OBJECTIVES: The aim of this study is to compare and evaluate the surface roughness of 2 dental ceramics (Noritake® & IPS Emax ceram) before and after exposure to an aerated drink, a mouthwash and simulated vomit solution with distilled water. MATERIALS AND METHODS: 128 ceramic discs were made, 16 for each of the 4 groups of 2 ceramics to be tested. It was fabricated in the form of discs of diameter 10 mm × 2 mm thickness. The test specimens were calibrated by grinding, using a medium grit diamond bur. Both the above specimens were divided into 4 groups of 16 each. They were then subjected to test solutions. Each specimen in a group was immersed in the following solutions: Coca-Cola, chlorhexidine mouthwash, simulated vomit solution and distilled water. RESULTS: The results analyzed statistically using one way ANOVA (analysis of variance), paired t test and independent t test. CONCLUSION: Within the limitations of this study, it was concluded that the surface roughness of the evaluated ceramics increased upon exposure to Coca-Cola, chlorhexidine mouthwash and simulated vomit solution. Simulated vomit solution caused the maximum change in surface roughness followed by coca cola and then chlorhexidine mouthwash. No changes were observed after immersion in distilled water. Noritake® showed slightly more resistance to change in surface profile when compared to IPS e.max.

Hearing Assessment of Dental Personnel: A Cross-sectional Exploratory Study.

AIM: Dental professionals are prone to have hearing impairment due to prolonged exposure of noise in dental college. The aim of the study was to assess the hearing ability of dental personnel working in Yenepoya Deemed to be University, Mangaluru, Karnataka, India. MATERIALS AND METHODS: A cross-sectional exploratory study was conducted on 60 subjects (30 male and 30 female). Audiometric analysis was carried out using pure-tone audiometry (PTA) and otoacoustic emission test (OAE). STATISTICAL ANALYSIS: Data were calculated and analyzed using two-way analysis of variance and Tukey's honestly significant difference test. RESULTS: No statistically significant difference was observed between hearing loss and its association with age, gender, working experience, mean daily working time, and specialization. PTA results showed a statistically significant hearing loss in the left ear, showing a dip at frequency of 4000 Hz among working experience group of 11-15 years and at 6000 Hz for 21-25 years. Also, a statistically significant hearing loss was observed in the left ear at 6000 and 8000 Hz for the age-group of 51-55 years. OAE results were consistent with PTA findings. CONCLUSION: Dentists and dental personnel are at a higher risk of noise-induced hearing loss. As the working experience increases, the threshold shift is seen to shift from 4000 to 6000 Hz, which is indicative of sensorineural hearing loss due to noise-induced dental environment.

A Novel Design Modification to Improve Flexural Strength of Zirconia Framework: A Comparative Experimental In Vitro Study.

AIM: Zirconia-based restoration is successfully replacing metal ceramic restorations in posterior areas. Although higher mechanical properties of zirconia, their use in compromised situation is questionable. Hence, there is a need to modify the design which to strengthen the framework. The aim of this in vitro study was to evaluate the influence of lingual collar design on the flexural strength of CAD/CAM-fabricated posterior three-unit zirconia framework. MATERIALS AND METHODS: A mandibular metallic stainless steel master mold is designed for a three-unit fixed partial denture framework. All CAD-milled 20 samples are divided into two groups based on the design. Group A--with collar (10 samples) and Group B--without collar (10 samples), tested using universal testing machine to calculate the mean fracture load and flexural strength. STATISTICAL ANALYSIS USED: Descriptive statistics and independent sample t test were used to find the difference between the groups, and simple linear regression was used to find the relationship between load and displacement between the groups. RESULTS: The result of the mean flexural strength for Group A was 11328.06 ± 3770MPa and for Group B was 7633.95 ± 3196MPa; the mean fracture strength observed for Group A was 1274.04 ± 424MPa and for Group B was 858.80 ± 359MPa. A statistically significant difference was observed in flexural strength between Groups A and B (P < 0.05). CONCLUSION: Zirconia framework with connector dimension of 7 mm2 with lingual collar design can be successfully incorporated in compromised situation where an ideal connector dimension of 9 mm2 cannot be placed.

Comparison of the Bond Strength of Composite Resin to Zirconia and Composite Resin to Polyether Ether Ketone: An In Vitro Study.

AIM: The aim of the study was to compare the shear bond strength of composite resin bonded to polyether ether ketone (PEEK) and zirconia, and also to evaluate the effect of thermocycling on the shear bond strength. MATERIALS AND METHODS: A total of 22 zirconia (Group 1) and 22 PEEK (Group 2) specimens (disks of 10 mm in diameter and 10 mm in thickness) were machine milled using computer-aided design (CAD)/computer-aided manufacturing (CAM) from commercially available zirconia and PEEK. These specimens were air abraded with 110-µm aluminum oxide. Following which these two groups were subdivided into four groups, that is, Group 1A: 11 zirconia specimens before thermocycling, Group 1B: 11 zirconia specimens after thermocycling, Group 2A: 11 PEEK specimens before thermocycling, and Group 2B: 11 PEEK specimens after thermocycling. These four groups of specimens were embedded in an acrylic block, and bonding agent was applied over the upper surfaces of the disks of each of these specimens. Composite resin was then cured, and then Group 1B and group 2B were thermocycled under a standard temperature. The bond strength of the specimen was tested using universal testing machine. RESULT: The result showed that there was no significant difference in shear bond strength between the groups, although higher shear bond strength was observed in the PEEK group. CONCLUSION: Shear bond strength of PEEK is similar to zirconia. The results suggest that the pretreatment method and primers used were effective in improving the bonding of resin cements to zirconia ceramic and the bonding properties of the veneering resin to the PEEK surface.

A Study to Assess the Bond Strength of Acrylic Teeth With Different Retentive Features.

BACKGROUND AND AIM: Flexible denture base has been gaining attention as a denture base material because of its toxicological safety, comfort, and enhanced aesthetics. Debonding of acrylic teeth from the flexible denture base material has posed a great problem to the clinician and patient. This study aimed at comparing the bond strength between flexible denture base with acrylic teeth having different mechanical modifications. MATERIALS AND METHODS: Forty mandibular molar teeth (Combination Acry Rock, Badia Polesine (Ro), Italy) were used in four groups for mechanical modifications on the ridge lap area. The groups were group 1 (no mechanical modifications), group 2 (round groove 2 mm in diameter and 2 mm deep on the ridge lap surface), group 3 (horizontal slot 2 mm deep, 2 mm wide, and 4 mm long prepared on the ridge lap surface of the teeth), and group 4 (T-shaped groove 2 mm deep, 2 mm wide, and length of 4 mm mesiodistally and 2 mm buccolingually prepared with a straight fissure bur). The acrylic teeth were attached to a wax block of dimension 1.2 cm × 1.2 cm × 2.5 cm. These were flasked and dewaxed, followed by injection molding with Valplast flexible denture base material. The bond strength was assessed by attaching the specimens to universal testing machine tested under a tensile load at a cross-head speed of 1 mm/min till it fractured. Data obtained were statistically evaluated by one-way analysis of variance and post hoc test. RESULTS: There was significant increase in mean bond strength after various mechanical modifications. Group with T-shaped diatoric hole showed greatest bond strength value compared to other groups. CONCLUSION: Incorporating mechanical retentive features with increased surface area and undercut can improve the bonding of acrylic teeth to flexible denture base.

Influence of Different Zirconia Coping Designs on the Fracture Resistance of All-Ceramic Crowns: An In Vitro Study.

BACKGROUND AND AIM: Increased demand for metal-free restorations in posterior areas has increased the focus on zirconia restorations because of its advantages in excellent mechanical properties, patient comfort, and acceptance. Although all-ceramic crowns have better biocompatibility and esthetic properties, there are some clinical reasons for the fracture of the veneer or the core materials in the posterior region. This study aims at comparing the influence of zirconia coping designs on the fracture resistance of all-ceramic crowns. MATERIALS AND METHODS: A total of 32 zirconia copings (n = 8 for each group) were designed and fabricated based on the marginal collar height of zirconia coping. The groups were the following: Group 1: 0.0 mm zirconia coping; Group 2: 0.5 mm collar; Group 3: 1.0 mm collar; and Group 4: 1.5 mm collar. All these zirconia copings were veneered with porcelain. Master die with cemented ceramic-layered zirconia copings was tested using Universal testing machine. Data obtained were statistically evaluated by one-way analysis of variance and post hoc test. RESULTS: There was statistically significant difference between the groups with P < 0.001. Group 4 has the highest strength (3318.89 ± 395.67) followed by Group 3 (2910.0 ± 219.22), then Group 1 (2320.02 ± 547.36) that is the control group and the least strength with Group 2 (2286.59 ± 496.66). CONCLUSION: On the basis of the results obtained from this study, it can be concluded that, the more the height of the zirconia collar, the higher the fracture strength of the all-ceramic crowns. Thus ceramic-layered zirconia coping design with 1.5 mm marginal collar height is recommended for functional long life, at least in the posterior higher load-bearing areas with lesser esthetic demands.

Evaluation of Fracture Resistance and Color Stability of Crowns Obtained by Layering Composite Over Zirconia and Polyetheretherketone Copings Before and After Thermocycling to Simulate Oral Environment: An In Vitro Study.

BACKGROUND: Most common material used for the fabrication of an implant restoration is full-ceramic crown or an all-ceramic crown. Frequent chipping of the ceramic under occlusal load has posed a great problem to the clinician and the patient. Composites have been layered over zirconia successfully in the recent past to overcome this problem. This study, thus, aimed to evaluate and compare the fracture resistance and color stability of crowns obtained by layering composite over zirconia and polyetheretherketone (PEEK) copings before and after thermocycling to simulate oral environment. MATERIALS AND METHODS: A total of 40 crowns (20 per group) were obtained by layering composite of A3 shade over computer-aided design/computer-aided milling milled zirconia and PEEK copings. Thermocycling of the 10 out of the 20 crowns was performed in a thermocycler (5000 cycles, in water temperature of 5°C and 55°C with dwell time of 30s), and then they were kept in hot and cold beverages for 24h each, to simulate oral environmental conditions. After thermocycling, the crowns were divided into four groups of 10 samples each: Group Z, ZT, P, and PT. Shade evaluation of all the crowns was performed using digital shade guide (VITA Easyshade® Advance; VITA Zahnfabrik, Bad Säckingen, Germany) and VITAPAN classical (VITA Zahnfabrik). Fracture strength was tested for all the crowns in a universal testing machine. Fracture strength in megapascal and the applied occlusal load in kilograms were recorded. Data obtained were statistically evaluated by one-way analysis of variance and post hoc test. RESULTS: The final shade of the crowns obtained by layering A3 shade composite in the groups Z was A3, ZT was B3, P was C3, and PT was D2. The value of mean fracture strength of crowns of groups Z was 1142.3MPa, ZT was 1034.57MPa, P was 2134.64MPa, and PT was 1765.01MPa. CONCLUSION: Thermocycling affected the shade of all the crowns. The mean fracture strength of the crowns having PEEK copings was significantly higher than that of zirconia copings. Thermocycling did not have a significant effect on the mean fracture strength.

Assessment of Periodontal Disease Among the Dental Prosthetic and Nonprosthetic Wearers in an Adult Rural Population in Mangalore Taluk, South India.

BACKGROUND: Oral health as an integral part of general health. Rural population neglect oral health as they lack awareness on oral diseases and also due to inadequate availability of dental services. There is a very high prevalence of chronic inflammatory periodontal disease in the rural Indian population, which is left untreated. Hence, this cross-sectional survey was taken up in the rural area of Mangalore taluk, Karnataka, India. MATERIALS AND METHODS: A cross-sectional survey was carried out on 1312 participants aged 18 years and older. The prevalence of periodontal disease among the dental prosthetic and nonprosthetic wearers was assessed. The World Health Organization format was used to record the periodontal status and loss of attachment. Data collected were analyzed using chi-square test. P < 0.05 was considered as significant. RESULT: Of the 1312 included subjects, 520 were males (39.6%) and 792 were females (60.3%). Periodontal status showed that calculus was found to be high among all age groups. When the prevalence of periodontal disease was assessed among the prosthetic wearers, it was found that subjects wearing removable partial denture showed increased prevalence of periodontal pocket depth and attachment loss irrespective of age group, gender, and educational qualification. CONCLUSION: Lack of awareness among the individuals regarding periodontal diseases has been associated with consistently higher prevalence of periodontal diseases and treatment needs. Demographical studies need to be carried out at regular intervals, thus helping in planning the treatment needs nationwide for better oral health care in rural population.

A clinico-radiographic study to compare and co-relate sagittal condylar guidance determined by intraoral gothic arch tracing method and panoramic radiograph in completely edentulous patients.

PURPOSE: The purpose of this study was to compare and correlate sagittal condylar guidance determined by intraoral gothic arch tracing method and panoramic radiograph in edentulous patients. MATERIALS AND METHODS: Twelve completely edentulous patients were selected by the inclusion and exclusion criteria. Conventional steps in the fabrication of complete denture till jaw relation were carried out. Intraoral gothic arch tracing and protrusive interocclusal records were obtained for each patient. Protrusive interocclusal record was used to program the Hanau Wide-Vue semi-adjustable articulator, thus obtaining the sagittal condylar guidance angle. Using RadiAnt DICOM software, on the orthopantomogram obtained for each patient in the study, two reference lines were drawn. The Frankfort's horizontal plane and the mean curvature line (joining the most superior and the inferior points on the glenoid fossa curvature) were drawn. The mean curvature line was extended to intersect the Frankfort's horizontal plane, thus obtaining the radiographic sagittal condylar guidance angle. The condylar guidance angles obtained by these two methods were compared and subjected to paired t-test. RESULTS: There was no statistically significant difference between the sagittal condylar guidance angles obtained between right and left sides with intraoral gothic arch tracing and radiographic methods (P = 0.107 and 0.07, respectively). CONCLUSION: Within the limitations of this study, it was concluded that the protrusive condylar guidance angles obtained by panoramic radiograph may be used for programming semi-adjustable articulators.

Nasal reconstruction with silicone using customised impression technique.

Facial defects can result from a variety of reasons including trauma, burns, infections, congenital disorders, and neoplasms which require surgical correction or prosthetic rehabilitation or both. Prosthetic replacement using various materials is the treatment of choice when other surgical options are not possible. This report presents a case of acquired nasal defect secondary to a surgically operated adenoid cystic carcinoma using silicone as the material of choice.

An In Vivo Study to Compare and Evaluate the Correlation of the Facial Measurements with the Combined Mesiodistal Width of the Maxillary Anterior Teeth between Males and Females.

AIM: The aim of this study was to compare and evaluate the correlation of the facial measurements (interalar, intercommissural, intercanthal, and interpupillary distance) with the combined mesiodistal width of the maxillary anterior teeth between males and females. OBJECTIVES: The objectives of this study were: (a) To evaluate the correlation of the facial measurements (interalar, intercommissural, intercanthal, and interpupillary distance) and combined mesiodistal width of maxillary anterior teeth. (b) To compare the correlation of the facial measurements (interalar, intercommissural, intercanthal, and interpupillary distance) with the combined mesiodistal width of maxillary anterior teeth between males and females. MATERIALS AND METHODS: This study was carried out on 120 dentate Subjects selected from Yenepoya Dental College, Mangalore. The vernier caliper was used to measure the interalar, intercommissural, intercanthal, and interpupillary distance. The mesiodistal width of maxillary anterior teeth was measured on the cast. For accuracy, every distance was measured three times and the mean taken. RESULTS: Comparison of parameters between males and females was calculated using independent sample t-test. The values obtained for each variables are interalar distance: for males 38.89 ± 2.19 and for females 35.58 ± 2.33. Intercommissural distance: for males 50.96 ± 2.99 and for females 47.15 ± 2.97. Intercanthal distance: for males 31.92 ± 1.46 and for females 30.46 ± 2.07. Interpupillary distance: for males 65.15 ± 2.82 and for females 61.78 ± 3.18. Mesiodistal width of maxillary anterior teeth: for males 52.55 ± 1.82 and for females 51.33 ± 2.50. CONCLUSION: Within the limitations of this study, the study concluded there is a significant correlation between interalar, intercommissural, intercanthal, interpupillary distance, and mesiodistal width of maxillary anterior teeth in total subjects. In females, there is a significant correlation between interalar, intercanthal, interpupillary distance, and mesiodistal width of maxillary anterior teeth.

Excision Versus Fixation of the Radial Head: A Comparative Study of the Functional Outcomes of the Two Techniques.

INTRODUCTION: The management of displaced and comminuted radial head fractures has been a matter of debate amongst surgeons for many years. Radial head excision formed the mainstay of surgical management of these injuries. Over the years, there have been improvements in the surgical techniques and availability of better implants and instrumentation techniques, hence, open reduction and internal fixation of these fractures is gaining popularity. AIM: To compare the outcome of elbow function between radial head excision and open reduction and internal fixation of the radial head with mini screws of Mason Type II and Type III radial head fractures and to assess the complications that occur in both techniques. MATERIALS AND METHODS: A prospective study was conducted in the Department of Orthopaedic Surgery of Justice K.S.Hegde Charitable hospital. A total of 40 patients between the age group of 30-50 years with Mason Type II and Type III fresh closed radial head fractures were included in the study. Group I consisted of 20 patients who underwent radial head excision and Group II consisted of 20 patients who underwent open reduction and internal fixation with mini screws. Patients were reviewed at postoperative week 3, 6 and 24. Radiographs were taken and functional outcome assessment of the elbow was done during all the follow ups. Elbow physiotherapy was started on postoperative week three. Scoring of elbow function was done as per the Disabilities of the Arm, Shoulder and Hand (DASH) scoring system. Results were tabulated, compared and analysed statistically using the 'chi-square test'. RESULTS: At the end of six months, the patients of the open reduction and internal fixation group had lower DASH scores (4.82±2.73 points) than the radial head excision group (14.23±5.60 points). This inferred that patients who underwent open reduction and internal fixation had better functional outcomes than the excision group. Complications of proximal radial migration was noted in three patients, elbow osteoarthritis was noted in two and periarticular ossification was noted in six patients who underwent radial head excision. CONCLUSION: Open reduction and internal fixation of Mason Type II and Type III radial head fractures is a better management technique as compared to radial head excision for management of Mason Type II and III radial head fractures.