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1.
J Environ Manage ; 368: 122084, 2024 Aug 08.
Artigo em Inglês | MEDLINE | ID: mdl-39121625

RESUMO

Accurately identifying the historical causes of carbon emissions in the process of national economic development is an important basis for developing countries to achieve carbon emission reduction. This paper explores the intrinsic institutional causes of China's high CO2 emission growth based on the characteristic economic growth target system of China, and attempts to empirically test the environmental effects behind this system. The results of the study show that the setting of absolute economic growth targets significantly increases the carbon dioxide emissions of cities under horizontal competition, and the setting of relative economic growth targets exacerbates the above carbon emission effect under vertical competition. In addition, the heterogeneity analysis shows that the carbon emission effect of setting economic growth targets is stronger in resource-dependent cities and cities with a lower level of economic development. Mechanism tests show that economic growth targets not only significantly increases total fossil energy consumption and reduces energy efficiency at the firm level, but also leads to the increase of energy consumption and the reduction of energy efficiency at the industry level. The findings of this study provide an intrinsic institutional explanation for China's high carbon emissions and provide useful guidance for the design of mechanisms to achieve large-scale carbon emission reductions in developing countries.

2.
Int J Mol Sci ; 25(13)2024 Jun 30.
Artigo em Inglês | MEDLINE | ID: mdl-39000340

RESUMO

Most α2-AR agonists derived from dexmedetomidine have few structural differences between them and have no selectivity for α2A/2B-AR or Gi/Gs, which can lead to side effects in drugs. To obtain novel and potent α2A-AR agonists, we performed virtual screening for human α2A-AR and α2B-AR to find α2A-AR agonists with higher selectivity. Compound P300-2342 and its three analogs significantly decreased the locomotor activity of mice (p < 0.05). Furthermore, P300-2342 and its three analogs inhibited the binding of [3H] Rauwolscine with IC50 values of 7.72 ± 0.76 and 12.23 ± 0.11 µM, respectively, to α2A-AR and α2B-AR. In α2A-AR-HEK293 cells, P300-2342 decreased forskolin-stimulated cAMP production without increasing cAMP production, which indicated that P300-2342 activated α2A-AR with coupling to the Gαi/o pathway but without Gαs coupling. P300-2342 exhibited no agonist but slight antagonist activities in α2B-AR. Similar results were obtained for the analogs of P300-2342. The docking results showed that P300-2342 formed π-hydrogen bonds with Y394, V114 in α2A-AR, and V93 in α2B-AR. Three analogs of P300-2342 formed several π-hydrogen bonds with V114, Y196, F390 in α2A-AR, and V93 in α2B-AR. We believe that these molecules can serve as leads for the further optimization of α2A-AR agonists with potentially few side effects.


Assuntos
Agonistas de Receptores Adrenérgicos alfa 2 , Simulação de Acoplamento Molecular , Receptores Adrenérgicos alfa 2 , Humanos , Animais , Células HEK293 , Receptores Adrenérgicos alfa 2/metabolismo , Agonistas de Receptores Adrenérgicos alfa 2/farmacologia , Camundongos , Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP/metabolismo , AMP Cíclico/metabolismo , Masculino , Ligação Proteica
3.
J Med Internet Res ; 26: e58174, 2024 Jul 31.
Artigo em Inglês | MEDLINE | ID: mdl-39083787

RESUMO

BACKGROUND: Developing adverse lifestyle behaviors increases the risk of a variety of chronic age-related diseases, including cardiovascular disease, obesity, and Alzheimer disease. There is limited evidence regarding the effectiveness of eHealth-based multiple health behavior change (MHBC) interventions to manage lifestyle risk behaviors. OBJECTIVE: The purpose of this systematic evaluation was to assess the effectiveness of eHealth MHBC interventions in changing ≥2 major lifestyle risk behaviors in people aged ≥50 years. METHODS: The literature search was conducted in 6 electronic databases-PubMed, Embase, Web of Science, Scopus, Cochrane Library, and SPORTDiscus-from inception to May 1, 2024. Eligible studies were randomized controlled trials of eHealth interventions targeting ≥2 of 6 behaviors of interest: alcohol use, smoking, diet, physical activity (PA), sedentary behavior, and sleep. RESULTS: A total of 34 articles with 35 studies were included. eHealth-based MHBC interventions significantly increased smoking cessation rates (odds ratio 2.09, 95% CI 1.62-2.70; P<.001), fruit intake (standardized mean difference [SMD] 0.18, 95% CI 0.04-0.32; P=.01), vegetable intake (SMD 0.17, 95% CI 0.05-0.28; P=.003), self-reported total PA (SMD 0.22, 95% CI 0.02-0.43; P=.03), and objectively measured moderate to vigorous PA (SMD 0.25, 95% CI 0.09-0.41; P=.002); in addition, the interventions decreased fat intake (SMD -0.23, 95% CI -0.33 to -0.13; P<.001). No effects were observed for alcohol use, sedentary behavior, or sleep. A sensitivity analysis was conducted to test the robustness of the pooled results. Moreover, the certainty of evidence was evaluated using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) framework. CONCLUSIONS: eHealth-based MHBC interventions may be a promising strategy to increase PA, improve diet, and reduce smoking among older adults. However, the effect sizes were small. Further high-quality, older adult-oriented research is needed to develop eHealth interventions that can change multiple behaviors. TRIAL REGISTRATION: PROSPERO International Prospective Register of Systematic Reviews CRD42023444418; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023444418.


Assuntos
Telemedicina , Humanos , Idoso , Pessoa de Meia-Idade , Exercício Físico , Estilo de Vida , Feminino , Masculino , Comportamentos Relacionados com a Saúde , Assunção de Riscos , Ensaios Clínicos Controlados Aleatórios como Assunto
4.
Digit Health ; 10: 20552076241239182, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38601186

RESUMO

Background: Despite the well-established health benefits of physical activity, a large population of older adults still maintain sedentary life style or physical inactivity. This network meta-analysis (NMA) aimed to compare the effectiveness of wearable activity tracker-based intervention (WAT), electronic and mobile health intervention (E&MH), structured exercise program intervention (SEP), financial incentive intervention (FI) on promoting physical activity and reducing sedentary time in older adults. Methods: The systematic review based on PRISMA guidelines, a systematic literature search of PubMed, Web of Science, Google Scholar, EMbase, Cochrane Library, Scopus were searched from inception to December 10th 2022. The randomized controlled trials (RCT) were included. Two reviewers independently conducted study selection, data extraction, risk of bias and certainty of evidence assessment. The effect measures were standard mean differences (SMD) and 95% confidence interval (CI) in daily steps, moderate-to-vigorous physical activity (MVPA) and sedentary time. Results: A total of 69 studies with 14,120 participants were included in the NMA. Among these included studies, the results of daily steps, MVPA and sedentary time was reported by 55, 25 and 15 studies, respectively. The NMA consistency model analysis suggested that the following interventions had the highest probability (surface under the cumulative ranking, SUCRA) of being the best when compared with control: FI + WAT for daily steps (SUCRA = 96.6%; SMD = 1.32, 95% CI:0.77, 1.86), WAT + E&MH + SEP for MVPA (SUCRA = 91.2%; SMD = 0.94, 95% CI: 0.36, 1.52) and WAT + E&MH + SEP for sedentary time (SUCRA = 80.3%; SMD = -0.50, 95% CI: -0.87, -0.14). The quality of the evidences of daily steps, MVPA and sedentary time was evaluated by very low, very low and low, respectively. Conclusions: In this NMA, there's low quality evidence that financial incentive combined with wearable activity tracker is the most effective intervention for increasing daily steps of older adults, wearable activity tracker combined with electronic and mobile health and structured exercise program is the most effective intervention to help older adults to increase MVPA and reduce sedentary time.

5.
Phytopathology ; 114(7): 1646-1656, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38648033

RESUMO

Actin filaments and their associated actin-binding proteins play key roles in plant innate immune signaling. CAP1, or cyclase-associated protein 1, is an important regulatory factor of the actin cytoskeleton-associated signaling network and was hypothesized here to be involved in resistance against wheat stripe rust because TaCAP1 expression was upregulated in response to Puccinia striiformis f. sp. tritici (Pst). Downregulation of TaCAP1 expression led to decreased resistance against Pst, in contrast to increased resistance upon TaCAP1 overexpressing, as demonstrated by the changes of phenotypes and hyphal growth. We found increased expression of pathogenesis-responsive or relative related genes and disease grade changed in TaCAP1 overexpressing plants. Our results also showed TaCAP1-regulated host resistance to Pst by inducing the production and accumulation of reactive oxygen species and mediating the salicylic acid signaling pathway. Additionally, TaCAP1 interacted with chlorophyll a/b-binding proteins TaLHCB1.3 and TaLHCB1.4, also known as the light-harvesting chlorophyll-protein complex II subunit B, which belong to the light-harvesting complex II protein family. Silencing of two TaLHCB1 genes showed higher susceptibility to Pst, which reduced wheat resistance against Pst. Therefore, the data presented herein further illuminate our understanding that TaCAP1 interacts with TaLHCB1s and functions as a positive regulator of wheat resistance against stripe rust.


Assuntos
Basidiomycota , Resistência à Doença , Regulação da Expressão Gênica de Plantas , Doenças das Plantas , Proteínas de Plantas , Puccinia , Triticum , Triticum/microbiologia , Triticum/genética , Triticum/imunologia , Doenças das Plantas/microbiologia , Doenças das Plantas/imunologia , Resistência à Doença/genética , Proteínas de Plantas/genética , Proteínas de Plantas/metabolismo , Puccinia/fisiologia , Basidiomycota/fisiologia , Espécies Reativas de Oxigênio/metabolismo , Ácido Salicílico/metabolismo , Transdução de Sinais , Plantas Geneticamente Modificadas
6.
Small ; 20(1): e2305200, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37649150

RESUMO

Artificially molding exciton flux is the cornerstone for developing promising excitonic devices. In the emerging hetero/homobilayers, the spatial separated charges prolong exciton lifetimes and create out-plane dipoles, facilitating electrically control exciton flux on a large scale, and the nanoscale periodic moiré potentials arising from twist-angle or/and lattice mismatch can substantially alter exciton dynamics, which are mainly proved in the heterostructures. However, the spatially indirect excitons dynamics in homobilayers without lattice mismatch remain elusive. Here the nonequilibrium dynamics of indirect exciton in homobilayers are systematically investigated. The homobilayers with slightly twist-angle can induce a deep moiré potential (>50 meV) in the energy landscape of indirect excitons, resulting in a strongly localized moiré excitons insulating the transport dynamics from phonons and disorder. These findings provide insights into the exciton dynamics and many-body physics in moiré superlattices modulated energy landscape, with implications for designing excitonic devices operating at room temperature.

8.
Geriatr Nurs ; 54: 318-323, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37939458

RESUMO

This study aimed to investigate the relationship between objectively measured step counts, step intensity and FOF in community-dwelling older Chinese women. Cross-sectional analyses were conducted on pooled data (n = 1101) from the baseline survey of the Physical Activity and Health Study (PAHIOWS). Step counts and step intensity were measured using wGT3X-BT accelerometers, and FOF was categorized into two levels (low and high) for logistic regression analysis. Higher step counts were significantly and negatively associated with FOF; however, after adjusting for step intensity, the association was no longer statistically significant. On the contrary, higher step intensity was negatively associated with FOF independent of step counts. This finding may provide new insights into the physical activity management of FOF in older women.


Assuntos
Medo , Vida Independente , Humanos , Feminino , Idoso , Estudos Transversais , China
9.
Int J Mol Sci ; 24(22)2023 Nov 16.
Artigo em Inglês | MEDLINE | ID: mdl-38003571

RESUMO

(1) Annexins are proteins that bind phospholipids and calcium ions in cell membranes and mediate signal transduction between Ca2+ and cell membranes. They play key roles in plant immunity. (2) In this study, virus mediated gene silencing and the heterologous overexpression of TaAnn12 in Arabidopsis thaliana Col-0 trials were used to determine whether the wheat annexin TaAnn12 plays a positive role in plant disease resistance. (3) During the incompatible interaction between wheat cv. Suwon 11 and the Puccinia striiformis f. sp. tritici (Pst) race CYR23, the expression of TaAnn12 was significantly upregulated at 24 h post inoculation (hpi). Silencing TaAnn12 in wheat enhanced the susceptibility to Pst. The salicylic acid hormone contents in the TaAnn12-silenced plants were significantly reduced. The overexpression of TaAnn12 in A. thaliana significantly increased resistance to Pseudomonas syringae pv. tomato DC3000, and the symptoms of the wild-type plants were more serious than those of the transgenic plants; the amounts of bacteria were significantly lower than those in the control group, the accumulation of Reactive Oxygen Species (ROS)and callose deposition increased, and the expression of resistance-related genes (AtPR1, AtPR2, and AtPR5) significantly increased. (4) Our results suggest that wheat TaAnn12 resisted the invasion of pathogens by inducing the production and accumulation of ROS and callose.


Assuntos
Arabidopsis , Basidiomycota , Resistência à Doença , Espécies Reativas de Oxigênio/metabolismo , Triticum/microbiologia , Anexinas/metabolismo , Regulação da Expressão Gênica de Plantas , Arabidopsis/metabolismo , Doenças das Plantas/microbiologia , Basidiomycota/metabolismo
10.
Sci Rep ; 13(1): 17811, 2023 Oct 19.
Artigo em Inglês | MEDLINE | ID: mdl-37857649

RESUMO

Nowadays environmental issues have been of great concern to the world, among which the problem of global warming caused by greenhouse gas emissions is particularly prominent. All countries in the Kyoto Protocol and the Paris Agreement have committed to control greenhouse gas emissions, and China, as the largest carbon emitter, has assumed a heavier burden. China has been striving to develop low-carbon technologies such as hydrogen, nuclear, wind, and solar energy, but the most attention should be paid to CCUS, which many scholars have high expectations that CCUS can help China reduce emissions to some extent. Therefore, this paper presents a prediction that CCUS can reduce 3.8% of carbon emissions for China in 2040 when CCUS emission reductions increase at a rate of 30%. The power and chemical industries could reduce carbon emissions by 2.3% and 17.3%, respectively.

11.
Front Public Health ; 11: 1241668, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37645705

RESUMO

Background: This study aimed to explore the association between physical activity (PA) and fear of falling (FOF) and to determine whether this relationship was mediated by physical fitness (PF) in community-dwelling older women. Methods: For this cross-sectional study, a total of 1,108 older women were recruited. Moderate-to-vigorous physical activity (MVPA) and light physical activity (LPA) were objectively measured by accelerometers. Physical fitness indicators including body mass index (BMI), forced vital capacity, choice reaction time, grip strength, sit and reach, and five times sit-to-stand were measured. FOF was evaluated by the Chinese version of the activities-specific balance confidence scale. A stepwise linear regression model analysis was used for mediation analysis, and bootstrap analysis was used to verify the mediation effects. Result: The Pearson correlation coefficient results suggested that MVPA was significantly and negatively correlated with FOF while LPA was not correlated with FOF. Logistic regression analysis suggested a significant association between MVPA, BMI, forced vital capacity, choice reaction time, sit and reach, grip strength, five times sit-to-stand, and FOF. The mediation analysis showed a negative relationship between MVPA and FOF. BMI completely mediated the relationship between MVPA and FOF while sit and reach, five times sit-to-stand, and forced vital capacity partially mediated the relationship between MVPA and FOF. Conclusion: Accumulation of more daily MVPA was associated with reducing the odds of FOF in community-dwelling older women. PF indicators fully or partially mediate the relationship between MVPA and FOF. Therefore, more intervention efforts should focus on the promotion of MVPA to improve PF and thus reduce FOF among older women.


Assuntos
Acidentes por Quedas , Vida Independente , Feminino , Humanos , Idoso , Acidentes por Quedas/prevenção & controle , Estudos Transversais , Medo , Exercício Físico , Aptidão Física , China
12.
Molecules ; 28(14)2023 Jul 24.
Artigo em Inglês | MEDLINE | ID: mdl-37513480

RESUMO

To study the use of partial or total potassium bicarbonate (PBC) to replace sodium tripolyphosphate (STPP) on reduced-phosphate silver carp batters, all the batters were composed of silver carp surimi, pork back fat, ice water, spices, sugar, and sodium chloride. Therein, the sample of T1 contained 4 g/kg STPP; T2 contained 1 g/kg PBC, 3 g/kg STPP; T3 contained 2 g/kg PBC, 2 g/kg STPP; T4 contained 3 g/kg PBC, 1 g/kg STPP; T5 contained 4 g/kg PBC, and they were all produced using a bowl chopper. The changes in pH, whiteness, water- and oil-holding capacity, gel and rheological properties, as well as protein conformation were investigated. The pH, cooking yield, water- and oil-holding capacity, texture properties, and the G' values at 90 °C of the reduced-phosphate silver carp batters with PBC significantly increased (p < 0.05) compared to the sample without PBC. Due to the increasing pH and enhanced ion strength, more ß-sheet and ß-turns structures were formed. Furthermore, by increasing PBC, the pH significantly increased (p < 0.05) and the cooked silver carp batters became darkened. Meanwhile, more CO2 was generated, which destroyed the gel structure, leading the water- and oil-holding capacity, texture properties, and G' values at 90 °C to be increased and then decreased. Overall, using PBC partial as a substitute of STPP enables reduced-phosphate silver carp batter to have better gel characteristics and water-holding capacity by increasing its pH and changing its rheology characteristic and protein conformation.


Assuntos
Carpas , Água , Animais , Água/química , Fosfatos , Reologia
13.
Artigo em Inglês | MEDLINE | ID: mdl-36613193

RESUMO

Previously conducted studies have established that the digital economy has a one-way inhibition effect on carbon emissions. Against this background, this paper aims to analyze the coordinated development effect of the interaction between the digital economy and carbon emissions reduction. The entropy weight method, coupling and coordination degree model, Dagum Gini coefficient and Moran's I index have been carried out as research methods in this paper. The results showed that: (1) The coupling and coordination of China's digital economy and carbon emissions reduction shows an overall growth trend, but the coupling and coordination among regions, provinces and cities show a large imbalance. (2) In the sample period, the overall difference in the coupling and coordination between digital economy development and carbon emissions reduction shows an expanding trend, and the overall difference results are attributed to regional differences. (3) There is a significant spatial correlation in the coupling and coordination degree of digital economy development and carbon emissions reduction among cities. The paper systematically grasps the status of coupling and coordination development, the source of difference and spatial correlation between the digital economy and carbon reduction in Chinese cities. A dependence relationship has been established, which is digital economy development and carbon emissions reduction, and an interactive promotion pattern has been revealed between the digital economic system and the carbon emissions reduction system.


Assuntos
Desenvolvimento Econômico , Humanos , Carbono , China , Cidades
14.
Light Sci Appl ; 12(1): 6, 2023 Jan 02.
Artigo em Inglês | MEDLINE | ID: mdl-36588111

RESUMO

Phonon-assisted photon upconversion (UPC) is an anti-Stokes process in which incident photons achieve higher energy emission by absorbing phonons. This letter studies phonon-assisted UPC in twisted 2D semiconductors, in which an inverted contrast between UPC and conventional photoluminescence (PL) of WSe2 twisted bilayer is emergent. A 4-fold UPC enhancement is achieved in 5.5° twisted bilayer while PL weakens by half. Reduced interlayer exciton conversion efficiency driven by lattice relaxation, along with enhanced pump efficiency resulting from spectral redshift, lead to the rotation-angle-dependent UPC enhancement. The counterintuitive phenomenon provides a novel insight into a unique way that twisted angle affects UPC and light-matter interactions in 2D semiconductors. Furthermore, the UPC enhancement platform with various superimposable means offers an effective method for lighting bilayers and expanding the application prospect of 2D stacked van der Waals devices.

15.
Inorg Chem ; 62(6): 2838-2847, 2023 Feb 13.
Artigo em Inglês | MEDLINE | ID: mdl-36709429

RESUMO

The development of a high current density with high energy conversion efficiency electrocatalyst is vital for large-scale industrial application of alkaline water splitting, particularly seawater splitting. Herein, we design a self-supporting Co3(PO4)2-MoO3-x/CoMoO4/NF superaerophobic electrode with a three-dimensional structure for high-performance hydrogen evolution reaction (HER) by a reasonable devise of possible "Co-O-Mo hybridization" on the interface. The "Co-O-Mo hybridization" interfaces induce charge transfer and generation of fresh oxygen vacancy active sites. Consequently, the unique heterostructures greatly facilitate the dissociation process of H2O molecules and enable efficient hydrogen spillover, leading to excellent HER performance with ultralow overpotentials (76 and 130 mV at 100 and 500 mA cm-2) and long-term durability of 100 h in an alkaline electrolyte. Theoretical calculations reveal that the Co3(PO4)2-MoO3-x/CoMoO4/NF promotes the adsorption/dissociation process of H2O molecules to play a crucial role in improving the stability and activity of HER. Our results exhibit that the HER activity of non-noble metal electrocatalysts can be greatly enhanced by rational interfacial chemical bonding to modulate the heterostructures.

16.
Sci Total Environ ; 854: 158598, 2023 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-36108849

RESUMO

Exposure to PM2.5 increases blood pressure (BP) and cardiovascular morbidity and mortality. We conducted a randomized controlled panel study in Shijiazhuang, China among 55 healthy college students randomly assigned to either the control (CON) or SPORTS group with intervention of 2000 m jogging in 20 min for 3 times in 4 days, and 3-round health examinations from November 15, 2020 to December 6, 2020. We aimed to evaluate whether moderate physical activity (PA) protected BP health against PM2.5 exposure and explore potential mechanisms through myokines and inflammation. Individual PM2.5 exposure was calculated based on outdoor and indoor PM2.5 concentration monitoring data as well as time-activity diary of each subject. In the CON group, the exposure-response curve for SBP was linear with a threshold concentration of approximately 31 µg/m3, while an increment of SBP level was 4.38 mm Hg (95%CI: 0.17 mm Hg, 8.59 mm Hg) at lag03 for each 10-µg/m3 increase in PM2.5, using linear mixed-effect models. For inflammatory indicators, PM2.5 exposure was associated with significant increases in eosinophil counts and proportion in CON group, but decreases in MCP-1 and TNF-α in SPORTS group. Meanwhile, higher myokines including CLU and IL-6 were observed in SPORTS group compared to the CON group. Further mediation analyses revealed that eosinophil counts mediated the elevated BP in CON group, whereas MCP-1 and TNF-α were also crucial mediating cytokines for the SPORTS group, as well as CLU and IL-6 acted as mediators on BP and inflammation indicators in SPORTS group. This study suggests that moderate PA could counteract the elevated BP induced by PM2.5 exposure via myokines-suppressed inflammation pathways.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Hipertensão , Humanos , Pressão Sanguínea , Poluentes Atmosféricos/toxicidade , Poluentes Atmosféricos/análise , Material Particulado/toxicidade , Material Particulado/análise , Exposição Ambiental/efeitos adversos , Exposição Ambiental/análise , Interleucina-6 , Fator de Necrose Tumoral alfa , Inflamação/induzido quimicamente , China , Exercício Físico , Poluição do Ar/análise
17.
Artigo em Inglês | MEDLINE | ID: mdl-36497614

RESUMO

Driven by the information technology revolution, using artificial intelligence to promote intelligent manufacturing while achieving carbon emissions reduction is increasingly the focus of international attention. Given this, based on the fact that China's industrial manufacturing is more intelligent, this paper uses industrial sector data and robot data from 2000 to 2017 to examine the impact of intelligent manufacturing on industrial carbon dioxide emissions and to discuss its internal mechanism. The research found that intelligent manufacturing significantly inhibits carbon dioxide emissions in the industrial sectors. The emission reduction effect is more obvious in industries with higher carbon emissions and intelligence. The mechanism test shows that intelligent manufacturing mainly achieves industrial emission reduction by reducing fossil energy consumption in the production process and improving energy use efficiency. The research findings of this paper provide favorable evidence for using new technologies, such as artificial intelligence, to achieve carbon emissions reduction, and validate the importance of intelligent manufacturing in tackling climate change in the future. It provides an essential reference for developing countries to use artificial intelligence for their carbon emissions reduction goals.


Assuntos
Inteligência Artificial , Dióxido de Carbono , Dióxido de Carbono/análise , Indústrias , Comércio , Mudança Climática , China , Desenvolvimento Econômico
18.
Comput Biol Med ; 148: 105885, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-35930957

RESUMO

Recurrent spontaneous abortion (RSA) is a frequent abnormal pregnancy with long-term psychological repercussions that disrupt the peace of the whole family. In the diagnosis and treatment of RSA worsened by thyroid disorders, recurrent spontaneous abortion is also a significant obstacle. The pathogenesis and possible treatment methods for RSA are yet unclear. Using clinical information, vitamin D and thyroid function measurements from normal pregnant women with RSA, we attempt to build a framework for conducting an effective analysis for RSA in this research. The framework is presented by combining the joint self-adaptive sime mould algorithm (JASMA) with the common kernel learning support vector machine with maximum-margin hyperplane theory, abbreviated as JASMA-SVM. The JASMA has a complete set of adaptive parameter change methods, which improves the algorithm's global search and optimization capabilities and guarantees that it speeds convergence and departs from the local optimum. On CEC 2014 benchmarks, the property of JASMA is validated, and then it is utilized to concurrently optimize parameters and select optimal features for SVM on RSA data from VitD, thyroid hormone levels, and thyroid autoantibodies. The statistical results demonstrate that the proposed JASMA-SVM can be treated as a potential tool for RSA with accuracy of 92.998%, MCC of 0.92425, sensitivity of 93.286%, specificity of 93.064%.


Assuntos
Aborto Habitual , Algoritmos , Feminino , Humanos , Gravidez , Máquina de Vetores de Suporte
19.
Artigo em Inglês | MEDLINE | ID: mdl-35897486

RESUMO

This study aimed to evaluate the effects of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) on cognitive flexibility in young adults with differing levels of aerobic fitness. Sixty-six young adults were grouped into high- and low-fit groups based on their final running distance on the 20 m Progressive Aerobic Cardiovascular Endurance Run (PACER) test. Individuals participated in a 10 min HIIE, a 20 min HIIE, a 20 min MICE, and a control session (reading quietly in a chair) in a counterbalanced order. The more-odd shifting task was completed before and approximately 5 min after each intervention to assess cognitive flexibility. The results showed that young adults with a high fitness level gained greater benefits in terms of switch cost from the 20 min HIIE, while low-fitness participants benefited more from the 10 min HIIE and the 20 min MICE. These findings suggest that aerobic fitness may influence the effect of acute HIIE and MICE on cognitive flexibility. Young adults should consider individual fitness level when adopting time-effective and appropriate exercise routines to improve cognitive flexibility.


Assuntos
Exercício Físico , Treinamento Intervalado de Alta Intensidade , Cognição , Treinamento Intervalado de Alta Intensidade/métodos , Humanos
20.
J Environ Manage ; 319: 115650, 2022 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-35820308

RESUMO

As a major carbon dioxide-emitting country, China set carbon trading market to reduce enterprise carbon emissions through the rational allocation of carbon quotas among different enterprises and regions. The market has also conducted a preliminary exploration for the country to achieve carbon dioxide emissions peak in 2030 and carbon neutrality in 2060 while actively addressing the challenges of global climate change. This study analysed the emission reduction effect of China's carbon trading pilot policy, especially the role of carbon quota and carbon trading price. The analysis used county-level panel data from 1997 to 2017, regarded the implementation of the carbon trading pilot policy as a quasi-natural experiment, and used the difference-in-differences method. The results showed that, first, the policy implementation not only reduced regional carbon emissions but also inhibited carbon dioxide emissions per capita, with long-term effects. Second, the carbon emission reduction effect brought by the carbon pilot policy showed significant heterogeneous results with the different degrees of regional carbon emissions and environmental supervision. The effect was greater in areas with higher carbon emission density and stronger legal supervision. Third, the difference in carbon quota allocations resulted in different emission reduction effects, among which the historical method had the strongest effect. The carbon quota price and number of enterprises participating carbon trading market were the key factors affecting carbon emission reduction.


Assuntos
Dióxido de Carbono , Gases de Efeito Estufa , China , Motivação , Políticas
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