Recurrence of Glandular Odontogenic Cysts: A Systematic Review.

BACKGROUND: The glandular odontogenic cyst (GOC) is a benign developmental cyst of the jaws that is characterized by a high recurrence rate. METHODS: A systematic review is presented of reported cases, case series, and retrospective studies of recurrent cases of glandular odontogenic cysts, to determine the overall and detailed demographic features with documentation of the specific histologic features of the initial presentation of each cyst. Searches of detailed databases were carried out to identify articles published in the English language from 1988 to 2023. The variables were demographics, patient symptoms, cyst location, radiographic features, histopathological findings, type of treatment, and minimum eight months of follow-up. RESULTS: Eighteen cases were identified: with an equal gender presentation of 50% females and 50% males. The average age was 44.7. The mean size was 3.5 cm. The most common location was in the anterior mandible in 50% (n = 9) of cases, followed by the posterior mandible 27.8% (n = 5). Most patients were asymptomatic 55.6% (n = 10). The most common histologic features at first diagnosis were mucous cells in 88.9% (n = 16), variable thickness with 83.3% (n = 15), eosinophilic cuboidal cells 88.9% (n = 16), microcysts 83.3% (n = 15), and clear cells 77.8% (n = 14) cases. CONCLUSION: GOC has an aggressive behavior. Evidence was not conclusive to link any single or combination of histologic features to recurrence, and the strongest correlation for recurrence was the type of treatment. Since this is an uncommon cyst, more cases are needed. Follow-up should continue for at least five years, because recurrences were higher between years 3 and 5.

Gender and Antimicrobial Resistance: What Can We Learn From Applying a Gendered Lens to Data Analysis Using a Participatory Arts Case Study?

Antimicrobial resistance (AMR), the natural process by which bacteria become resistant to the medicines used to kill them, is becoming one of the greatest threats to health globally. AMR is accelerating at alarming rates due to behaviors across human, animal, and environmental health sectors as well as governance and policy shortfalls across each sector. Antimicrobial resistant infections occur through the same channels as other infectious diseases and are most common in countries/areas where there is limited access to improved sanitation facilities, reliable healthcare and health education. At the community level, much remains to be understood about the drivers of antimicrobial resistance and how to generate community-led, acceptable solutions. Gender can influence every part of an individual's health experiences; access to knowledge, healthcare facilities, financial resources and paid employment are all heavily gendered and influence behaviors relating to the procurement of antimicrobial and antibiotic agents. This analysis uses data gathered during a participatory video study designed to work with two communities in Nepal to understand drivers of antibiotic mis and over use from the perspective of the communities themselves. Findings reveal that gender impacts upon many aspects of AMR-driving behaviors within this community and stimulate essential discussion as to the importance of gender in future AMR research. This paper places a spotlight on gender in the wider AMR conversation, an area that is currently neglected, and improve our collective knowledge on the drivers of AMR from a gendered perspective.

Mean Fluoride Concentration in Drinking Water Sources of a Municipality: A Descriptive Cross-sectional Study.

Introduction: Fluoride is essential for the growth and development of teeth and bone. Excess or less fluoride consumption can have harmful effects on our bodies. Fluoride level of 0.5-1.5 mg/l is said to be optimized according to the World Health Organization. The level of fluoride varies among the different geographical regions and water sources. It is essential to find out the fluoride content of various water sources used for drinking purposes. The aim of this study was to find the mean concentration of fluoride in drinking water sources of a municipality. Methods: A descriptive cross-sectional study was conducted in a Municipality. The study was conducted from 1 December 2021 to 30 December 2021 after receiving ethical approval from the Ethical Review Board (Reference number: 1134). Water samples were collected and the fluoride content was estimated using 2-parasulfophenylazo-1,8-dihydroxy-3,6-napthalene-disulfonate colorimetric method. The data collected from the laboratory were calculated and presented in the form of a table. Point estimate and 95% Confidence Interval were calculated. Results: The mean value of fluoride content in 160 collected water samples was 0.369±0.275 mg/l (0.33-0.41, 95% Confidence Interval). Among the different wards, the fluoride content was 0.708±0.27 mg/l in ward number 12 followed by a fluoride content of 0.57±0.19 mg/l in ward number 5. Conclusions: In this study, the mean fluoride levels were lower when compared with similar studies conducted in similar settings. The levels were lower than that recommended by the World Health Organization. The various controlled methods of fluoridation have to be quickly initiated. Other means of fluoride consumption, like the use of fluoridated toothpaste, has to be recommended. Keywords: dental caries; drinking water; fluoride.

The values and principles underpinning community engagement approaches to tackling antimicrobial resistance (AMR).

This paper presents seven values underpinning the application of Community Engagement (CE) approaches to the One Health challenge of antimicrobial resistance (AMR) developed during an international workshop in June 2019. We define a value as a quality or standard which a CE project is aiming for, whilst a principle is an objective which underpins the value and facilitates its achievement. The values of Clarity, Creativity, (being) Evidence-led, Equity, Interdisciplinarity, Sustainability and Flexibility were identified by a network of 40 researchers and practitioners who utilise CE approaches to tackle complex One Health challenges including, but not limited to, AMR. We present our understanding of these seven values and their underlying principles as a flexible tool designed to support stakeholders within CE for AMR projects. We include practical guidance on working toward each value, plus case studies of the values in action within existing AMR interventions. Finally, we consider the extent to which CE approaches are appropriate to tackle AMR challenges. We reflect on these in relation to the tool, and current literature for both CE and AMR research. Authors and co-producers anticipate this tool being used to scene-set, road map and trouble shoot the development, implementation, and evaluation of CE projects to address AMR and other One Health challenges. However, the tool is not prescriptive but responsive to the context and needs of the community, opening opportunity to build a truly collaborative and community-centred approach to AMR research.