Factors affecting nutritional knowledge, attitude, practices and dietary intake among national players in Kathmandu, Nepal: a cross-sectional study.

INTRODUCTION: Good nutrition knowledge and nutrient intake have been regarded as significant determinants in enhancing athletes' performance and overall health status. This study aimed to assess knowledge, attitude, and practices of nutrition and dietary intake among athletes. METHODS: A cross-sectional study was conducted from January to April 2022 among national athletes from two sports clubs in Kathmandu Metropolitan City, Nepal. A semi-structured questionnaire was used to collect the data. Anthropometric measurements and dietary intake were recorded. Bivariate and multivariate binary logistic regression was used to estimate the crude odds ratios (cOR), and adjusted odds ratios (aOR) with 95% confidence intervals (CIs). RESULTS: A total of 270 players were included in this study (mean age, 25 years; 49.6% male, 50.4% female). Almost half of the athletes had good nutrition knowledge [54.1% (146/270)], attitude [56.7% (153/270)], and practices [50% (135/270)] scores. The mean energy, carbohydrate, protein, and fat intake were 35.0 kcal/kg/day, 5.6, 0.9, and 0.9 g/kg/day, respectively. Likewise, mean calcium and iron intake were 370, and 12.5 mg, respectively. In the multivariate model, families with monthly household income less than 50,000 Nepalese rupees ($400) (adjusted Odds Ratio/aOR = 2.58; 95% CI: 1.12 to 5.96), and those who did not receive diet plan (aOR = 3.14; 95% CI: 1.25 to 7.84) were more likely to have poor nutrition knowledge. Players who did not check food labelling (aOR = 1.44; 95% CI: 0.78 to 2.63) were more likely to have negative attitude towards nutrition. Players who did not ever attend nutrition class (aOR = 3.54; 95% CI: 1.46 to 8.54) and those who did not consume different food during off and on the season of sports (aOR = 2.36; 95% CI: 1.39 to 4.01) were more likely to have poor nutrition practice. CONCLUSIONS: Half of the athletes' nutritional knowledge, attitudes, and practices score were satisfactory. Nutrient intake among athletes was suboptimal. Nutrition intervention programs are critical to improve nutritional knowledge, attitude and practice related to dietary intake among national athletes in Nepal.

Crops' response to the emergent air pollutants.

MAIN CONCLUSION: Consequences of air pollutants on physiology, biology, yield and quality in the crops are evident. Crop and soil management can play significant roles in attenuating the impacts of air pollutants. With rapid urbanization and industrialization, air pollution has emerged as a serious threat to quality crop production. Assessing the effect of the elevated level of pollutants on the performance of the crops is crucial. Compared to the soil and water pollutants, the air pollutants spread more rapidly to the extensive area. This paper has reviewed and highlighted the major findings of the previous research works on the morphological, physiological and biochemical changes in some important crops and fruits exposed to the increasing levels of air pollutants. The crop, soil and environmental factors governing the effect of air pollutants have been discussed. The majority of the observations suggest that the air pollutants alter the physiology and biochemical in the plants, i.e., while some pollutants are beneficial to the growth and yields and modify physiological and morphological processes, most of them appeared to be detrimental to the crop yields and their quality. A better understanding of the mechanisms of the uptake of air pollutants and crop responses is quite important for devising the measures ‒ at both policy and program levels ‒ to minimize their possible negative impacts on crops. Further research directions in this field have also been presented.

Guideline based knowledge and practice of physicians in the management of COPD in a low- to middle-income country.

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death, with 80% of the total death occurring in low- to middle-income countries (LMICs). Nepal is one of the LMIC; COPD is a highly prevalent and significant public health issue often underdiagnosed. Medical physicians' good knowledge and practice to diagnose and treat COPD can help reduce the disease burden. OBJECTIVES: To determine the level of knowledge, practice and factors influencing the practice of physicians regarding COPD management based on GOLD guidelines. DESIGN: A cross-sectional descriptive study using a structured questionnaire was conducted among medical physicians working in Bagmati and Gandaki province of Nepal. Out of total scores, physicians knowledge and practice were graded according to Bloom's original cut-off point for good (≥80%), satisfactory (60%-78%) and poor (<60%). RESULT: A total of 152 medical physicians participated in this study. Out of the possible total score 20, the mean score on knowledge was 17.8 ± 2.4, and out of possible total score eight, the mean score on practice was 5.3 ± 1.3. The correlation test between total knowledge and practice scores showed r = 0.18 and p value <0.02. The most selected factors hindering the appropriate management of COPD was lack of patient follow up and lack of professional training in COPD. Other factors included patient unwillingness to discuss smoking quit plan, lack of screening tool, unavailability of spirometry and physician unawareness of available medicine to treat COPD. CONCLUSION: Despite physicians having good knowledge in COPD, the practice in COPD management is below guideline-recommended. There is a significant, very low positive correlation between total knowledge score and practice score. Proper COPD training to physicians, disease awareness among patients, easy availability of diagnostic equipment and medication can help improve physicians' practice and appropriately manage COPD patients.

A Bibliometric Analysis on Nonpoint Source Pollution: Current Status, Development, and Future.

Nonpoint source pollution (NPS) has become the leading factor of global water quality problems, attracting great attention from governments and researchers in various countries. Based on this situation, understanding the current research status of NPS can help guide future research. However, most of the current reviews only describe the research status of some specific aspects but fail to quantify the research hotspots and development trends on the whole, which limits the overall understanding of NPS. In this paper, bibliometrics was used to study the current status, hotspots, and frontiers of NPS research during 1991-2015, and the future research development was predicted. Over the past 15 years, there has been a remarkable growth trend in publication output, and the participation of countries/territories has also increased. Journal of Environmental Quality, Journal of Hydrology, and Total Environmental Science were the top three journals. Sharpley AN and Arnold JG from the USA were the most productive authors with the best quality articles. The major author clusters and research regions are located in North America and Europe, followed by East Asia. The United States dominates this research field, with the largest number of independent and collaborative articles. Chinese authors gained more attention through international cooperation. Keyword analysis confirmed that water quality and nutrients were the main concerns of NPS pollution research, which mainly involved a number of research topics, such as pollutant emission reduction research and the evaluation and simulation of pollutants' migration and their transformation under different situations, while pesticides were less of a concern, which suggests that the abuse of pesticides has come under control. Meanwhile, SWAT was the dominating model in the last decade partly because it satisfied the growing needs of watershed-scale management.

Digital soil mapping in the Bara district of Nepal using kriging tool in ArcGIS.

Digital soil mapping has been widely used to develop statistical models of the relationships between environmental variables and soil attributes. This study aimed at determining and mapping the spatial distribution of the variability in soil chemical properties of the agricultural floodplain lands of the Bara district in Nepal. The study was carried out in 23 Village Development Committees with 12,516 ha total area, in the southern part of the Bara district. A total of 109 surface soil samples (0 to 15 cm depth) were collected and analyzed for pH, organic matter (OM), nitrogen (N), phosphorus (P, expressed as P2O5), potassium (K, expressed as K2O), zinc (Zn), and boron (B) status. Descriptive statistics showed that most of the measured soil chemical variables (other than pH and P2O5) were skewed and non-normally distributed and logarithmic transformation was then applied. A geostatistical tool, kriging, was used in ArcGIS to interpolate measured values for those variables and several digital map layers were developed based on each soil chemical property. Geostatistical interpolation identified a moderate spatial variability for pH, OM, N, P2O5, and a weak spatial variability for K2O, Zn, and B, depending upon the use of amendments, fertilizing methods, and tillage, along with the inherent characteristics of each variable. Exponential (pH, OM, N, and Zn), Spherical (K2O and B), and Gaussian (P2O5) models were fitted to the semivariograms of the soil variables. These maps allow farmers to assess existing farm soils, thus allowing them to make easier and more efficient management decisions and maintain the sustainability of productivity.

Pediatric Central Nervous System Tumors in Nepal: Retrospective Analysis and Literature Review of Low- and Middle-Income Countries.

BACKGROUND: Central nervous system (CNS) tumors are the most common cause of cancer-related death in children. Little is known about the demographics and treatment of pediatric brain tumors in low- and middle-income countries (LMICs). METHODS: We performed a retrospective chart review of all pediatric patients who presented to the neurosurgical service at Tribhuvan University Teaching Hospital in Kathmandu, Nepal from 2009-2014 and collected information on patients <18 years old who received a diagnosis of a CNS tumor. We analyzed age, gender, clinical presentation, extent of surgical resection, histopathology, and length of hospital stay. We also conducted a literature review using specific terminology to capture studies of pediatric neuro-oncologic epidemiology conducted in LMICs. Study location, length of study, sample size, study type, and occurrence of 4 common pediatric brain tumors were extracted. RESULTS: We identified 39 cases of pediatric CNS tumors, with 62.5% observed in male children. We found that male children (median = 13 years) presented later than female children (median = 8 years). The most frequently observed pediatric brain tumor type was ependymoma (17.5%), followed by astrocytoma (15%) and medulloblastoma (15%). Surgical resection was performed for 80% of cases, and gross total resection reported in 62.9% of all surgeries. More than half (54.1%) of patients had symptoms for more than 28 days before seeking treatment. Symptomatic hydrocephalus was noted in 57.1% of children who presented with CNS tumors. The literature review yielded studies from 18 countries. Study length ranged from 2-20 years, and sample sizes varied from 35-1948. Overall, we found more pronounced variation in the relative frequencies of the most common pediatric brain tumors, compared with high-income countries. CONCLUSIONS: We present the first operative series of childhood CNS tumors in Nepal. Children often had delayed diagnosis and treatment of a tumor, despite symptoms. More comprehensive data are required to develop improved treatment and management algorithms in the context of a given country's demographics and medical capabilities for childhood CNS tumors.

Phenotypic variation in the plant pathogenic bacterium Acidovorax citrulli.

Acidovorax citrulli causes bacterial fruit blotch (BFB) of cucurbits, a disease that threatens the cucurbit industry worldwide. Despite the economic importance of BFB, little is known about pathogenicity and fitness strategies of the bacterium. We have observed the phenomenon of phenotypic variation in A. citrulli. Here we report the characterization of phenotypic variants (PVs) of two strains, M6 and 7a1, isolated from melon and watermelon, respectively. Phenotypic variation was observed following growth in rich medium, as well as upon isolation of bacteria from inoculated plants or exposure to several stresses, including heat, salt and acidic conditions. When grown on nutrient agar, all PV colonies possessed a translucent appearance, in contrast to parental strain colonies that were opaque. After 72 h, PV colonies were bigger than parental colonies, and had a fuzzy appearance relative to parental strain colonies that are relatively smooth. A. citrulli colonies are generally surrounded by haloes detectable by the naked eye. These haloes are formed by type IV pilus (T4P)-mediated twitching motility that occurs at the edge of the colony. No twitching haloes could be detected around colonies of both M6 and 7a1 PVs, and microscopy observations confirmed that indeed the PVs did not perform twitching motility. In agreement with these results, transmission electron microscopy revealed that M6 and 7a1 PVs do not produce T4P under tested conditions. PVs also differed from their parental strain in swimming motility and biofilm formation, and interestingly, all assessed variants were less virulent than their corresponding parental strains in seed transmission assays. Slight alterations could be detected in some DNA fingerprinting profiles of 7a1 variants relative to the parental strain, while no differences at all could be seen among M6 variants and parental strain, suggesting that, at least in the latter, phenotypic variation is mediated by slight genetic and/or epigenetic alterations.