Characterization of women with cervical cancer assisted at Inca by histological type.

OBJECTIVE: To determine the distribution of sociodemographic, reproductive, clinical and lifestyle habits in the cohort of women diagnosed with cervical cancer, assisted at Inca between 2012 and 2014, according to the histological type. METHODS: Retrospective observational study of a hospital cohort of 1,004 women diagnosed with cervical cancer. Data were obtained from the Inca hospital cancer registry, physical and electronic records. RESULTS: The most frequent histological type was squamous cell carcinoma (83.9%). Approximately 70% of the women aged more than 40 years. The study includes non-white women (67.4%), with less than 8 years of education (51.9%), with onset of sexual activity up to 16 years of age (40.7%), who were pregnant before (95.5%), with more than one pregnancy (82.9%), and more than two children (52.7%); 45.8% of the women were smokers or former smokers. Cervical adenocarcinoma was positively associated with earlier staging (IA-IIA) (OR = 1.79; 95%CI 1.03-3.13), as well as women with ≥ 12 years of education (OR = 6.30; 95%CI 1.97-20,13), who had no children (OR = 3.81; 95%CI 1.20 - 12,08) or who had up to two children (OR = 1.74; 95%CI 1.05 - 2,87). CONCLUSIONS: The difference between histological types is highlighted, suggesting that women with cervical adenocarcinoma may represent a distinct clinical entity of cervical neoplasia, which may require different approaches from those used in squamous cell carcinoma.

Characterization of women with cervical cancer assisted at Inca by histological type / Caracterização de mulheres com câncer cervical atendidas no Inca por tipo histológico

ABSTRACT OBJECTIVE To determine the distribution of sociodemographic, reproductive, clinical and lifestyle habits in the cohort of women diagnosed with cervical cancer, assisted at Inca between 2012 and 2014, according to the histological type. METHODS Retrospective observational study of a hospital cohort of 1,004 women diagnosed with cervical cancer. Data were obtained from the Inca hospital cancer registry, physical and electronic records. RESULTS The most frequent histological type was squamous cell carcinoma (83.9%). Approximately 70% of the women aged more than 40 years. The study includes non-white women (67.4%), with less than 8 years of education (51.9%), with onset of sexual activity up to 16 years of age (40.7%), who were pregnant before (95.5%), with more than one pregnancy (82.9%), and more than two children (52.7%); 45.8% of the women were smokers or former smokers. Cervical adenocarcinoma was positively associated with earlier staging (IA-IIA) (OR = 1.79; 95%CI 1.03-3.13), as well as women with ≥ 12 years of education (OR = 6.30; 95%CI 1.97-20,13), who had no children (OR = 3.81; 95%CI 1.20 - 12,08) or who had up to two children (OR = 1.74; 95%CI 1.05 - 2,87). CONCLUSIONS The difference between histological types is highlighted, suggesting that women with cervical adenocarcinoma may represent a distinct clinical entity of cervical neoplasia, which may require different approaches from those used in squamous cell carcinoma.

RESUMO OBJETIVO Determinar a distribuição das características sociodemográficas, reprodutivas, clínicas e de hábitos de vida na coorte de mulheres diagnosticadas com câncer cervical, atendidas no Inca entre 2012 e 2014, segundo o tipo histológico. MÉTODOS Estudo observacional retrospectivo de uma coorte hospitalar de 1.004 mulheres diagnosticadas com câncer cervical. Os dados foram obtidos pelo Registro Hospitalar de Câncer do Inca, prontuários físicos e eletrônicos. RESULTADOS O tipo histológico mais frequente foi o carcinoma de células escamosas (83,9%). Aproximadamente 70% das mulheres foram diagnosticadas com mais de 40 anos de idade. Houve a predominância de mulheres não brancas (67,4%), com menos de 8 anos de escolaridade (51,9%), com início da atividade sexual até 16 anos de idade (40,7%), que já engravidaram alguma vez na vida (95,5%), com mais de uma gestação (82,9%) e mais de dois filhos (52,7%); 45,8% das mulheres eram tabagistas ou ex-tabagistas. O adenocarcinoma cervical esteve positivamente associado ao estadiamento mais precoce (IA-IIA) (OR = 1,79; IC95% 1,03-3,13), assim como a mulheres com ≥ 12 anos de estudo (OR = 6,30; IC95% 1,97-20,13), que não tiveram filhos (OR = 3,81; IC95% 1,20-12,08) ou que tiveram até dois filhos (OR = 1,74; IC95% 1,05-2,87). CONCLUSÕES Destaca-se a diferença entre os tipos histológicos, sugerindo que as mulheres com adenocarcinoma cervical possam representar uma entidade clínica distinta de neoplasia cervical, podendo demandar abordagens diferentes das utilizadas no carcinoma de células escamosas.

Avaliação do tempo de espera no manejo terapêutico e seus efeitos na sobrevida de mulheres diagnosticadas com câncer de colo de útero em uma coorte hospitalar no INCa-II

O câncer cervical é um grave problema de saúde pública nos países em desenvolvimento, cuja mortalidade pode ser afetada por diversos fatores, como o atraso para o encaminhamento e tratamento na unidade hospitalar de referência. Avaliar os tempos de espera no tratamento prescrito segundo os fatores sociodemográficos, ambientais e clínicos, e os seus efeitos na sobrevida de mulheres diagnosticadas e tratadas com câncer do colo de útero nos anos de 2012 a 2014. Estudo observacional retrospectivo de uma coorte hospitalar de mulheres diagnosticadas com câncer de colo de útero e tratadas no INCa/II. Os dados foram obtidos pelo Registro Hospitalar de Câncer/INCa, prontuário físicos e eletrônicos, e do sistemas de faturamento hospitalar. Os intervalos analisados foram divididos notempo entre : o diagnóstico e o atendimento no INCa (T1), o diagnóstico e o início do tratamento (T2), o diagnóstico e final do tratamento (T3), o início e fim do tratamento (T4), o início da radioterapia e final da braquiterapia (T5), o final da radioterapia e início da braquiterapia (T6). As. (...)um tempo de espera maior que o recomendado pela literatura. Os intervalos até o tratamento apresentaram forte associação com o baixo nível sócio econômico e com o estadiamento avançado. Porém, o estadiamento avançado não teve a sobrevida afetada, devido à urgência na realização do tratamento pelas piores condições clínicas da mulher. O maior tempo dos diferentes tratamentos realizados, apresentou fatores relacionados ao sistema. Apenas o atraso entre início e término do tratamento afetou estatisticamente a sobrevida em 36 meses na coorte estudada.

Cervical cancer is a serious public health problem in developing countries, where mortality can be affected by several factors including the delay for referral and treatment in the hospital of reference. To assess waiting times the prescribed treatment according to sociodemographic factors, environmental and clinical, and its effects on the survival of women diagnosed and treated with cervical cancer in the years 2012-2014. This is a study retrospective observational hospital of a cohort of women diagnosed with cervical cancer and treated at the INCa / II. Data were obtained from the Hospital Cancer Register / INCa, physical and electronic records, and hospital billing systems. The intervals analyzed were divided into time between diagnosis and care in INCa (T1),between diagnosis and initiation of treatment (T2), between diagnosis and completion of treatment (T3) between the beginning and end of treatment (T4) between the beginning and end of the radiation and end of brachytherapy (T5) between the top end of radiotherapy and initiation of brachytherapy (T6). Patients. (...). All intervals presented a wait time much higher than recommended in the literature. Intervals to treatment were strongly associated with low socioeconomic level and the advanced stage. However, the advanced stage was not affected survival due to the urgency in making the treatment the worst clinical conditions of women. The longer the different treatments performed, presented factors related to the system. But only the delay between the beginning and end of treatment statistically affect survival at 36 months in the study cohort.