Integrative Approach to Address Male Infertility: A Case Study on Organophosphorus Compound Exposure and Traditional Medicinal Interventions.

Factors, including exposure to substances like organophosphorus compounds (OPCs), have been linked to fertility issues, which are a growing concern. In this case study, a 29-year-old farmer and his 26-year-old wife, married for the past five years, faced challenges conceiving despite several attempts. It was found that the husband's exposure to OPCs like chlorpyrifos, malathion, diazinon, etc., had impacted the quality of his sperm. However, after undergoing treatments and making lifestyle changes such as panchakarma therapy and taking Shilajit supplements, there was an improvement in sperm quality. Through in vitro fertilization using physiological intracytoplasmic sperm injection, successful fertilization and the development of high-quality blastocysts were achieved. This case demonstrates the potential for addressing infertility caused by toxins through a blend of traditional medicinal practices and modern reproductive technologies. It underscores the need for research into strategies that can reduce the effects of OPC exposure on male fertility.

Shunt connection: An intelligent skipping of contiguous blocks for optimizing MobileNet-V2.

Enabling deep neural networks for tight resource constraint environments like mobile phones and cameras is the current need. The existing availability in the form of optimized architectures like Squeeze Net, MobileNet etc., are devised to serve the purpose by utilizing the parameter friendly operations and architectures, such as point-wise convolution, bottleneck layer etc. This work focuses on optimizing the number of floating point operations involved in inference through an already compressed deep learning architecture. The optimization is performed by utilizing the advantage of residual connections in a macroscopic way. This paper proposes novel connection on top of the deep learning architecture whose idea is to locate the blocks of a pretrained network which have relatively lesser knowledge quotient and then bypassing those blocks by an intelligent skip connection, named here as Shunt connection. The proposed method helps in replacing the high computational blocks by computation friendly shunt connection. In a given architecture, up to two vulnerable locations are selected where 6 contiguous blocks are selected and skipped at the first location and 2 contiguous blocks are selected and skipped at the second location, leveraging 2 shunt connections. The proposed connection is used over state-of-the-art MobileNet-V2 architecture and manifests two cases, which lead from 33.5% reduction in flops (one connection) up to 43.6% reduction in flops (two connections) with minimal impact on accuracy.