Convalescent plasma therapy and remdesivir duo successfully salvaged an early liver transplant recipient with severe COVID-19 pneumonia.

The impact and clinical spectrum of COVID-19 infection in liver transplant recipients/solid organ transplants are being unveiled during this recent pandemic. The clinical experience of use of current antiviral drugs and immunomodulators are sparse in solid organ transplantation. We present the clinical course of a 49-year-old male recipient who underwent living donor liver transplant for recurrent gastrointestinal bleed and contracted severe COVID-19 pneumonia during the third postoperative week. Herein we report the successful management of severe COVID-19 pneumonia using convalescent plasma therapy and remdesivir. Recipient's clinical deterioration was halted after three consecutive convalescent plasma transfusions with improvement in hypoxia and inflammatory markers (interleukin-6 and C-reactive protein). The use of convalescent plasma therapy along with remdesivir may be an ideal combination in the management of severe COVID-19 pneumonia in solid organ transplant recipients.

High-dose morphine for intractable phantom limb pain.

Phantom limb pain is difficult to treat as existing therapies have limited effectiveness and what works for one person may not work for another. This makes the fact that research is ongoing and advancing even more important to many people who have this problem. We are reporting a case of intractable phantom limb pain whose pain did not respond to usual line of treatment and only high dose of morphine made the patient totally pain free.

Intravesical lidocaine for formalin-induced suprapubic pain: case report.

This case report describes the management of intravesical formalin induced suprapubic pain using intravesical lidocaine.