Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros

Ano de publicação
Tipo de documento
Intervalo de ano de publicação
1.
Hemoglobin ; 41(2): 83-88, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28589738

RESUMO

Brazilian Quilombolas are communities composed of African-derived populations that have their territories guaranteed by the Brazilian Constitution. The present study investigated the hemoglobin (Hb) variants among these population groups. This study was conducted in a total of 2843 individuals of Brazilian Quilombola communities of the Bahia, Pará, and Piauí states. All the participants had their Hb profiles evaluated. The Hb S (HBB: c.20A>T) variant was described in all the studied localities. However, the individuals in Bahia State had the highest frequency of the Hb C (HBB: c.19G>A) variant; individuals from Piauí State had a higher frequency of the Hb D-Punjab (HBB: c.364G>C) variant compared to the other states, and individuals from Pará State only carried the Hb S variant. The present study revealed a specific distribution of Hb variants that could represent different waves of African influence in these Brazilian populations.


Assuntos
Frequência do Gene , Hemoglobina Falciforme/genética , Hemoglobinas Anormais/genética , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Brasil , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
2.
Rev. bras. hematol. hemoter ; 31(6): 471-472, 2009. graf
Artigo em Português | LILACS | ID: lil-540380

RESUMO

The most highly prevalent inherited disease in Brazil and in the world, sickle cell anemia, is considered a public health problem. Characterized by homozygosis for the hemoglobin S gene, the individual has a range of signs and symptoms that require careful treatment. The sickle cell trait is characterized by heterozygosis for the hemoglobin S gene, however the carrier does not express the disease. In the current study we aimed at verifying the presence of the sickle cell trait in 1000 blood donors of the Hematology and Hemotherapy Center of the State of Piauí (Hemopi) in the period from October 2007 to April 2008. After analysis by alkaline and acid electrophoresis, positive cases were confirmed by molecular biology. We obtained rates of 3.4 percent for hemoglobin AS and 5 percent for hemoglobin AC, with a total frequency of 3.9 percent in the total of 1,000 blood donors.


Assuntos
Humanos , Anemia Falciforme , Doadores de Sangue , Hemoglobinas
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA