1.
J Org Chem
; 73(12): 4644-9, 2008 Jun 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18505288
RESUMO
Butanone side chains at arenes and hetarenes, efficiently introduced by a Heck-type reaction, are transformed to annulated thieno[3,2-b]thiophenes in a domino redox process under Willgerodt-Kindler conditions. A nucleophilic aromatic substitution with an intermediary thioenolate is a reasonable key step of this process.