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1.
Toxicology ; 463: 152967, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34619302

RESUMO

Blister agents damage the skin, eyes, mucous membranes and subcutaneous tissues. Other toxic effects may occur after absorption. The response of the Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) to a request from the OPCW Director-General in 2013 on the status of medical countermeasures and treatments to blister agents is updated through the incorporation of the latest information. The physical and toxicological properties of sulfur mustard and clinical effects and treatments are summarised. The information should assist medics and emergency responders who may be unfamiliar with the toxidrome of sulfur mustard and its treatment.


Assuntos
Substâncias para a Guerra Química/intoxicação , Gás de Mostarda/intoxicação , Animais , Humanos , Contramedidas Médicas
2.
Toxicology ; 413: 13-23, 2019 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-30500381

RESUMO

The Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) has provided advice in relation to the Chemical Weapons Convention on assistance and protection. We present the SAB's response to a request from the OPCW Director-General in 2014 for information on the best practices for preventing and treating the health effects from acute, prolonged, and repeated organophosphorus nerve agent (NA) exposure. The report summarises pre- and post-exposure treatments, and developments in decontaminants and adsorbing materials, that at the time of the advice, were available for NAs. The updated information provided could assist medics and emergency responders unfamiliar with treatment and decontamination options related to exposure to NAs. The SAB recommended that developments in research on medical countermeasures and decontaminants for NAs should be monitored by the OPCW, and used in assistance and protection training courses and workshops organised through its capacity building programmes.


Assuntos
Comitês Consultivos/normas , Substâncias para a Guerra Química/toxicidade , Descontaminação/normas , Contramedidas Médicas , Agentes Neurotóxicos/toxicidade , Antídotos/uso terapêutico , Descontaminação/métodos , Humanos , Países Baixos , Compostos Organofosforados/toxicidade , Resultado do Tratamento
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