The impact of the COVID-19 pandemic on physical activity, life satisfaction, anxiety, stress perception and coping strategies in student-athletes: A comparison between Belarus and Poland-countries with a different approach of anti-pandemic measures.

Background: More than two years of the COVID-19 pandemic has changed lives of people around the world and had a profound impact on the field of sports. This has resulted in decreased physical activity (PA) and changes in mental health. The goal was to assess self-reported physical activity, life satisfaction, perceived stress, choice of coping strategies and their correlations among student athletes from two neighboring countries facing different anti-pandemic strategies. Methods: Cross-sectional surveys using standardized questionnaires: International Physical Activity Questionnaire-Short Form (IPAQ-SF), Satisfaction With Life Scale (SWLS), State-Trait Anxiety Inventory (STAI), Perceived Stress Scale (PSS-10), and Coping Orientation to Problems Experienced (Mini-COPE) to compare 600 students from Physical Education and Sports departments of universities in Belarus (n = 333), where restrictions were found to be less stringent than in neighboring Poland (n = 267). Results: Minor differences in physical activities between both countries indicate that student athletes have adapted fairly quickly and found ways to keep their PA at a fairly high level. Nevertheless, higher PA was reported in the group of student athletes from Belarus. PA levels correlated with life satisfaction, anxiety and stress levels. Female students from Poland reported lower satisfaction with their lives. Their perception of stress was twice as high as that of their Belarusian counterparts. The most common coping strategy in both groups was active coping. Polish respondents less frequently used strategies of avoiding problems and seeking outside support. Conclusion: The level of physical activity and well-being of student athletes are associated with increased mental health and coping with stress. They also contribute to prevention of affective disorders during the COVID-19 pandemic. Moreover, it is dependent on the country's anti-pandemic policies.

Physical Activity, Life Satisfaction, Stress Perception and Coping Strategies of University Students in Belarus during the COVID-19 Pandemic.

The COVID-19 restrictions in Belarus turned out to be less stringent than those of its neighboring countries. Objective: We aimed to evaluate physical activity, life satisfaction, perception of stress, choice of coping strategies and their correlations among Belarusian students. An anonymous Internet survey was conducted among 1769 students studying at the faculties of physical culture (415), pedagogical (737), and medical (617) universities. International Physical Activity Questionnaires (IPAQ) and Satisfaction With Life Scale (SWLS), Perceived Stress Scale-10 (PSS-10), and Coping Orientations to Problems Experienced (mini-COPE) questionnaires were used. The respondents declared sufficient and high levels of physical activity. The level of physical activity was correlated with life satisfaction (typically for student-athletes). The least satisfaction with life and highest level of perceived stress were among future doctors. The minimum indicator of stress was noted in athletes. The most common coping strategy was active coping. Strategies of problem avoidance and seeking support from outside were not used by student-athletes. These strategies were used by pedagogical and medical students. Student-athletes have the most favorable opportunities, followed by representatives of pedagogical and medical students. The proposed classification of the levels of behavior (optimal, acceptable, satisfactory and risky) makes it possible to adjust lifestyles.

Exogenous mammalian extracellular HSP70 reduces endotoxin manifestations at the cellular and organism levels.

In this study, we checked whether HSP70 preparations of different origins are able to protect model animals (rats) from endotoxic shock and modify the response of myeloid cells to lipopolysaccharide (LPS) challenge. It was shown that HSP70 preparations can effectively protect organisms from endotoxic shock by strongly decreasing mortality and restoring both homeostasis and various hemodynamic characteristics. At the cellular level, HSP70 preparations significantly inhibit LPS-induced reactive oxygen species production in various myeloid cells and decrease NO expression in macrophages, which is enhanced after LPS priming. In parallel, HSP70 preconditioning partially normalizes neutrophil apoptosis, which is disturbed as a result of LPS stimulation. These results suggest that the antiseptic actions of HSP70 preparations are probably realized at the level of receptor membrane complexes of myeloid cells, which represent the major target of LPS action. Taken together, our findings show that extracellular mammalian HSP70 may play an important role in innate immunity modulation and stimulation of endogenous protective mechanisms, both at the cellular and organism levels, which make this protein a promising base for the development of efficient antiseptic drugs.