RESUMO
Phyllodes tumors of the breast are uncommon, and 6.2% of phyllodes tumors behave in a malignant fashion. The metastatic spread of malignant phyllodes tumor is mainly hematogenous to lung and bone, and malignant phyllodes tumor metastasizing to the ovary is rare, with only 2 cases reported. We report the third case of metastatic malignant phyllodes tumor to the ovary with a focus on the differential diagnosis of ovarian cancer.
Assuntos
Neoplasias da Mama , Neoplasias Ovarianas , Tumor Filoide , Mama/patologia , Neoplasias da Mama/diagnóstico , Feminino , Humanos , Neoplasias Ovarianas/diagnóstico , Tumor Filoide/diagnóstico , Tumor Filoide/patologiaRESUMO
A 61-year-old man developed double vision subsequent to diarrheal illness. Mixed horizontal-vertical gaze palsy in both eyes, diminution of tendon reflexes, and gaze nystagmus were noted. His horizontal gaze palsy was accompanied by gaze nystagmus in the abducent direction, indicative of the disturbance in central nervous system. Neither limb weakness nor ataxia was noted. Serum anti-GQ1b antibody was detected. Brain magnetic resonance imaging (MRI) findings were normal. The patient was diagnosed as having acute ophthalmoparesis. The ophthalmoparesis and nystagmus gradually disappeared in 3 months. The accompanying nystagmus suggests that central nervous system disturbance may also be present with acute ophthalmoparesis.
Assuntos
Nistagmo Patológico/etiologia , Oftalmoplegia/etiologia , Doença Aguda , Biomarcadores/sangue , Gangliosídeos/imunologia , Humanos , Imunoglobulina G/sangue , Masculino , Pessoa de Meia-Idade , Síndrome de Miller Fisher/complicações , Síndrome de Miller Fisher/diagnósticoRESUMO
Short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) is a rare primary headache syndrome. The diagnostic criteria include attacks of unilateral orbital, supraorbital or temporal stabbing pain accompanied by one of the following: conjunctival injection and/or tearing, nasal congestion and/or rhinorrhea, and eyelid edema. The duration of pain is 2 seconds to 10 minutes, and the frequency of attacks is described as once a day or more. The etiology and pathology of SUNA has yet to be documented. We report an 18-year-old man with SUNA. Lomerizine hydrochloride which is used as a preventive medicine for migraine, improved his headaches.
Assuntos
Síndrome SUNCT/diagnóstico , Adolescente , Analgésicos/uso terapêutico , Nervos Cranianos , Humanos , Imageamento por Ressonância Magnética , Masculino , Neuralgia , Piperazinas/uso terapêutico , Síndrome SUNCT/tratamento farmacológicoRESUMO
Pseudomigraine with pleocytosis (PMP) is an uncommon disease in Japan. The diagnostic criteria include at least one episode of transient neurological deficit accompanied or followed by migraine-like severe headache, cerebrospinal fluid (CSF) lymphocytosis, and normal neuroimaging. Both the etiology and the pathophysiology of PMP is not yet well defined. We report a 40-year-old man with a PMP-like syndrome. He came to our clinic because of severe throbbing headache and amnesia, and the examination showed CSF lymphocytosis of 23/mm3, a transient decrease of cerebral blood flow in the left thalamus. All the symptoms were completely resolved within 2 months.
Assuntos
Amnésia/epidemiologia , Encéfalo/irrigação sanguínea , Linfocitose/líquido cefalorraquidiano , Linfocitose/epidemiologia , Transtornos de Enxaqueca/epidemiologia , Adulto , Comorbidade , Lobo Frontal/fisiopatologia , Humanos , Masculino , Fluxo Sanguíneo Regional , Síndrome , Lobo Temporal/fisiopatologia , Tálamo/fisiopatologia , Fatores de Tempo , Tomografia Computadorizada de Emissão de Fóton ÚnicoRESUMO
A 17-year-old boy without a significant past medical history presented with recurrent cluster-like headaches induced by meals for 3 years. Magnetic resonance images showed a pituitary tumor. Just after starting treatment with cabergoline, the headaches resolved completely and the patient has been absolutely free from such headache attacks for 2 years.
Assuntos
Antineoplásicos/uso terapêutico , Cefaleia Histamínica/etiologia , Ergolinas/uso terapêutico , Neoplasias Hipofisárias/tratamento farmacológico , Prolactinoma/tratamento farmacológico , Adolescente , Cabergolina , Ingestão de Alimentos , Humanos , Masculino , Neoplasias Hipofisárias/complicações , Prolactinoma/complicações , Recidiva , Resultado do TratamentoRESUMO
The n-hexane and ethyl acetate extracts of the stems and the ethyl acetate extracts of roots from Prangos pabularia afforded an gamma-pyrone derivative and furanocoumarin derivatives with three glucose and gamma-pyrone (pabularin A, B and C), along with 26 previously known compounds (18 coumarins, six terpenoids and two glycosides). Their structures were established on the basis of spectroscopic studies. Of these, 16 coumarin derivatives isolated from P. pabularia were tested for antibacterial activity and inhibition of cytokine release.