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1.
Clin Oncol (R Coll Radiol) ; 23(3): 216-22, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21185700

RESUMO

AIMS: The treatment of patients with synchronous bilateral breast cancer is a challenge. We present a report of dosimetric data of patients with bilateral chest walls as the target treated with electron arc therapy. MATERIALS AND METHODS: Ten consecutive patients who had undergone electron arc therapy to the bilateral chest wall for breast cancer were analysed. After positioning and immobilisation, patients underwent computed tomography scans from the neck to the upper abdomen. Electron arc plans were generated using the PLATO RTS (V1.8.2 Nucletron) treatment planning system. Electron energy was chosen depending upon the depth and thickness of the planning target volume (PTV). For all patients, the arc angle ranged between 80 and 280° (start angle 80°, stop angle 280°). The homogeneity index, coverage index and doses to organs at risk were evaluated. The patient-specific output factor and thermoluminescence dosimetry (TLD) measurements were carried out for all patients. The total planned dose to the PTV was 50Gy/25 fractions/5 weeks. RESULTS: The mean PTV (± standard deviation) was 568.9 (±116)cm(3). The mean PTV coverage was 89 (±5.8)% of the prescribed dose. For the right lung, the mean values of D(1) and D(10) were 46 (±7.6) and 30 (±9)Gy, respectively. For the left lung, the mean values of D(1) and D(10) were 45 (±7) and 27 (±8)Gy, respectively. For the heart, the mean values of D(1), D(5) and D(10) were 21 (±15), 13.5 (±12) and 9 (±9)Gy, respectively. The mean values of TLD at various pre-specified locations on the chest wall surface were 1.84, 1.82, 1.82, 1.89 and 1.78Gy, respectively CONCLUSION: The electron arc technique for treating the bilateral chest wall is a feasible and pragmatic technique. This technique has the twin advantages of adequate coverage of the target volume and sparing of adjacent normal structures. However, compared with other techniques, it needs a firm quality assurance protocol for dosimetry and treatment delivery.


Assuntos
Neoplasias da Mama/patologia , Neoplasias da Mama/radioterapia , Planejamento da Radioterapia Assistida por Computador/métodos , Radioterapia/métodos , Parede Torácica/efeitos da radiação , Feminino , Humanos , Radiometria , Dosagem Radioterapêutica
2.
Australas Phys Eng Sci Med ; 30(2): 127-34, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17682402

RESUMO

A new model of the telecobalt unit (TCU), Theratron Equinox-80, (MDS Nordion, Canada) equipped with a single 60 degree motorized wedge (MW), four universal wedges (UW) for 15 degrees, 30 degrees, 45 degrees and 60 degrees have been evaluated. MW was commissioned in Eclipse (Varian, Palo Alto, USA) 3D treatment planning system (TPS). The profiles and central axis depth doses (CADD) were measured with Wellhofer blue water phantom for MW and the measured data was commissioned in Eclipse. These profiles and CADD for MW were compared with UW in a homogeneous phantom generated in Eclipse for various field sizes. The dose was also calculated in the same phantom at 10 cm depth. For the particular MW angle and the respective open and MW beam weights, the dose was measured for a field size of 10 cm x 10 cm in a MEDTEC water phantom at 10 cm depth with a 0.13 cc thimble ion chamber (Scanditronix Wellhofer, Uppsala, Sweden) and a NE electrometer (Nuclear Enterprises, UK). Measured dose with ion chamber was compared with the TPS calculated dose. MW angle verification was also done on the Equinox for four angles (15 degrees, 30 degrees, 45 degrees and 60 degrees). The variation in measured and calculated dose at 10 cm depth was within 2%. The measured and the calculated wedge angles were in good agreement within 2 degrees. The motorized wedges were successfully commissioned in Eclipse for four wedge angles.


Assuntos
Cobalto , Imagens de Fantasmas , Planejamento da Radioterapia Assistida por Computador/instrumentação , Dosagem Radioterapêutica , Fatores de Tempo
3.
Australas Phys Eng Sci Med ; 30(1): 25-32, 2007 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17508598

RESUMO

Purpose of this study was to report in a together our experience of using ion chambers, TLD, MOSFET and EDR2 film for dosimetric verification of IMRT plans delivered with dynamic multileaf collimator (DMLC). Two ion chambers (0.6 and 0.13 CC) were used. All measurements were performed with a 6MV photon beam on a Varian Clinac 6EX LINAC equipped with a Millennium MLC. All measurements were additionally carried out with (LiF:Mg,TI) TLD chips. Five MOSFET detectors were also irradiated. EDR2 films were used to measure coronal planar dose for 10 patients. Measurements were carried out simultaneously for cumulative fields at central axis and at off-axis at isocenter plane (+/- 1, and +/- 2 cm). The mean percentage variation between measured cumulative central axis dose with 0.6 cc ion chamber and calculated dose with TPS was -1.4% (SD 3.2). The mean percentage variation between measured cumulative absolute central axis dose with 0.13 cc ion chamber and calculated dose with TPS was -0.6% (SD 1.9). The mean percentage variation between measured central axis dose with TLD and calculated dose with TPS was -1.8% (SD 2.9). A variation of less than 5% was found between measured off-axis doses with TLD and calculated dose with TPS. For all the cases, MOSFET agreed within +/- 5%. A good agreement was found between measured and calculated isodoses. Both ion chambers (0.6 CC and 0.13 CC) were found in good agreement with calculated dose with TPS.


Assuntos
Radiometria/instrumentação , Planejamento da Radioterapia Assistida por Computador/instrumentação , Radioterapia Conformacional/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Humanos , Radiometria/métodos , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador/métodos , Radioterapia Conformacional/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
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