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Interact Cardiovasc Thorac Surg ; 7(2): 184-7, 2008 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-18089616

RESUMO

Junctional ectopic tachycardia (JET) is a major cause of postoperative morbidity after complete repair of tetralogy of Fallot (TOF). Propranolol is a known medication used in patients with TOF to prevent and control hypercyanotic spells. Despite this, there is little information regarding the relation between preoperative use of propranolol and the incidence of postoperative JET. The aim of this study was to examine the effect of preoperative use of propranolol on the incidence of postoperative JET after full surgical repair of TOF. A retrospective analysis of 109 patients in whom 57 patients received preoperative propranolol (propranolol group) was compared with 52 patients who did not receive propranolol preoperatively (control group). The incidence of postoperative JET was significantly higher in the control group (38%) than the propranolol group (21%) P=0.042. The propranolol group had significantly less mechanical ventilation time, less ICU stay and less total hospital stay than the control group (P<0.05). Our findings suggest that the preoperative use of propranolol may decrease the incidence of JET after full surgical repair of TOF. A prospective randomized study may help to elucidate the exact relationship between the preoperative use of propranolol and the incidence of postoperative JET.


Assuntos
Antiarrítmicos/uso terapêutico , Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Propranolol/uso terapêutico , Taquicardia Ectópica de Junção/prevenção & controle , Tetralogia de Fallot/cirurgia , Pré-Escolar , Cuidados Críticos , Feminino , Seguimentos , Humanos , Incidência , Lactente , Tempo de Internação , Masculino , Projetos de Pesquisa , Respiração Artificial , Estudos Retrospectivos , Taquicardia Ectópica de Junção/epidemiologia , Taquicardia Ectópica de Junção/etiologia , Fatores de Tempo , Resultado do Tratamento
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