RESUMO
All 899 roommates exposed to methicillin-resistant Staphylococcus aureus (MRSA) index cases were studied over 57 months. MRSA detection is better at approximately 3 days (50%-55%) or 7 days (56%) after contact has been broken than day 0 (30%). Polymerase chain reaction testing at day 3 performs similarly to culture at day 7. Nasal/rectal screening provides superior detection than nasal alone. Those exposed >48 hours are at significantly greater risk of colonization.
Assuntos
Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Quartos de Pacientes , Infecções Estafilocócicas/epidemiologia , Infecções Estafilocócicas/transmissão , Técnicas Bacteriológicas/métodos , Humanos , Controle de Infecções/métodos , Programas de Rastreamento/métodos , Mucosa Nasal/microbiologia , Reação em Cadeia da Polimerase/métodos , Reto/microbiologia , Infecções Estafilocócicas/microbiologia , Fatores de TempoRESUMO
All medical and high-risk surgical patients were screened for methicillin-resistant Staphylococcus aureus colonization over 3.5 years. The sensitivities of nasal and rectal swabs were 68% and 62%, respectively. Naris and open-skin-site swabs detected 467 (74%) of 627 adult carriers identified. Rectal swabs detected an additional 160 (26%) carriers.
Assuntos
Staphylococcus aureus Resistente à Meticilina , Mucosa Nasal/microbiologia , Reto/microbiologia , Infecções Estafilocócicas/diagnóstico , Adulto , Portador Sadio/microbiologia , Infecção Hospitalar/microbiologia , Humanos , Vigilância da População , Sensibilidade e EspecificidadeRESUMO
An updated IDI-MRSA assay version was released to address the assay's low positive predictive value (PPV). A prospective analysis of two assay versions indicated no significant improvement in the PPV. Colonization by methicillin-resistant Staphylococcus aureus in 24% of patients would not have been detected if only nasal samples had been tested, as approved, by this molecular method.