RESUMO
Changes in plasma fibronectin (FN) levels in acute toxic conditions have been studied in 24 patients. A significant reduction of FN concentration was found within the first days of the disease; further changes in the FN levels are related to the disease outcome and have a prognostic value. An inverse correlation was found between the FN concentration and other blood biochemical parameters (LDH, creatinine, and urea). Developed renal insufficiency in the presence of hypofibronectinemia suggests a poor prognosis of the disease.
Assuntos
Fibronectinas/sangue , Intoxicação/sangue , Doença Aguda , Humanos , PrognósticoRESUMO
The authors have developed a complex of measures including the known (tetrapolar rheoplethysmography, liver and kidney radiography) and the new tests (soft tissue scintigraphy) that have been used for the first time in this condition. Employment of these tests for the examination and monitoring the treatment of patients who were injured in the earthquake in Armenia has helped quantitatively assess the structural and functional shifts in the vital organs and injured limbs in the crush syndrome, thus being valuable for the organization and monitoring the efficacy of therapy and for predicting the outcome of injury.
Assuntos
Injúria Renal Aguda/diagnóstico , Traumatismos do Braço/diagnóstico , Síndrome de Esmagamento/diagnóstico , Desastres , Hemodinâmica/fisiologia , Rim/fisiopatologia , Traumatismos da Perna/diagnóstico , Choque Traumático/diagnóstico , Injúria Renal Aguda/etiologia , Injúria Renal Aguda/fisiopatologia , Braço/irrigação sanguínea , Traumatismos do Braço/complicações , Traumatismos do Braço/fisiopatologia , Armênia , Síndrome de Esmagamento/complicações , Síndrome de Esmagamento/fisiopatologia , Humanos , Testes de Função Renal , Perna (Membro)/irrigação sanguínea , Traumatismos da Perna/complicações , Traumatismos da Perna/fisiopatologia , Pletismografia de ImpedânciaRESUMO
The principle 'rehabilitation starts in a resuscitation ward' has been realized in the resuscitation treatment of 34 patients with the prolonged crush syndrome (PCS) who were injured during the earthquake in Armenia. Laser therapy has been fairly effective, normalizing the external respiration function and central hemodynamics and reducing the blood coagulability. Instrumental vibration massage and acupuncture are recommended to be added to rehabilitation treatment of PCS patients.