Hypertension in postmenopausal Indonesian Women: fluctuating Body Mass Index as a potential predictor of decreasing blood pressure.

Background: The burden of Hypertension (HT) [P1][YT2] in Indonesian postmenopausal women has increased over the past years. Obesity is the most prevalent risk of HT among postmenopausal women. Objective: This study evaluates the relationship of fluctuating BMI with BP in postmenopausal women in Bogor, Indonesia. Methods: This longitudinal study acquired secondary data from a previous study of the "Cohort Study of NCD' Risk Factors" along with a two-year follow-up. Data were analyzed from a total of 888 postmenopausal women aged ≥ 25 years[P3][wr4]. BMI and BP fluctuations were calculated from baseline BMI at the first visit (T1) until the observation period (T7). The significance of panel analysis at p value < 0.05.[P5][wr6]. Results: The fixed-effect model showed a significant correlation between BMI changes with the changes in SBP and DBP and fluctuating BMI with SBP. After adjustment for physical activity, 1 kg of weight gain will increase SBP and DBP in normotensive, controlled, and uncontrolled hypertensive individuals. After adjusting for smoking, BMI reduction by 1% would lower the SBP as much as 2-3 mmHg compared to a stable BMI. Conclusions: Fluctuating BMI was a predictor in decreasing BP in postmenopausal women, so it could be used to control HT.

A systematic review and meta-analysis of dementia prevalence in seven developing countries: A STRiDE project.

The STRiDE project sets out to support the development of effective dementia policy in middle-income countries (Brazil, India, Indonesia, Jamaica, Kenya, Mexico, and South Africa). As part of this it will generate new data about the prevalence of dementia for a subset of these countries. This study aims to identify the current estimates of dementia prevalence in these countries and where the gaps lie in the current literature. A systematic review was completed on 30th April 2019 across electronic databases, identifying dementia prevalence literature originating from any of the seven countries. Four hundred and twenty-nine records were identified following de-duplication; 28 studies met the inclusion criteria and were included in the systematic review. Pooled estimates of dementia prevalence ranged from 2% to 9% based on DSM-IV criteria; these figures were generally higher in studies using other diagnostic criteria (e.g. the 10/66 algorithm). Available prevalence data varied between countries. Only Brazil, Mexico and India had data derived from studies judged as having a low risk of bias. Irrespective of country, studies often were not explicit in detailing the representativeness of their sample, or whether there was non-response bias. Further transparent and externally valid dementia prevalence research is needed across the STRiDE countries.