RESUMO
The problem of antibiotic-associated conditions is one of the most actual problems of clinical practice. The antibiotic-associated diarrhea is a multidisciplinary problem. Investigations of the small intestine microecological status and assessment of microflora at the patients receiving antibiotics testifies to dysbiosis existence. In article results of open-label investigation of a multispecies probiotic RioFlora Balance using for antibiotic-associated diarrhea prophylaxis in patients used antibacterial therapy are presented.
Assuntos
Antibacterianos/efeitos adversos , Colo/microbiologia , Diarreia/microbiologia , Diarreia/prevenção & controle , Probióticos/uso terapêutico , Adulto , Antibacterianos/administração & dosagem , Antibacterianos/uso terapêutico , Broncopneumonia/tratamento farmacológico , Colo/efeitos dos fármacos , Diarreia/induzido quimicamente , Fezes/microbiologia , Feminino , Humanos , Masculino , Probióticos/administração & dosagem , Resultado do TratamentoAssuntos
Anti-Inflamatórios não Esteroides/efeitos adversos , Gastroenteropatias/prevenção & controle , Inibidores da Bomba de Prótons/uso terapêutico , Anti-Inflamatórios não Esteroides/administração & dosagem , Anti-Inflamatórios não Esteroides/uso terapêutico , Comportamento de Escolha , Diabetes Mellitus/tratamento farmacológico , Interações Medicamentosas , Gastroenteropatias/induzido quimicamente , Gastroenteropatias/metabolismo , Humanos , Hipertensão/complicações , Hipertensão/tratamento farmacológico , Isquemia Miocárdica/complicações , Isquemia Miocárdica/tratamento farmacológico , Obesidade/complicações , Obesidade/tratamento farmacológico , Osteocondrose/complicações , Osteocondrose/tratamento farmacológico , Padrões de Prática Médica , Inibidores da Bomba de Prótons/administração & dosagem , Inibidores da Bomba de Prótons/efeitos adversosRESUMO
In this article result of medication methocinium iodide (Methacin) using at patients with irritable bowel syndrome are observed.
Assuntos
Síndrome do Intestino Irritável/tratamento farmacológico , Antagonistas Muscarínicos/administração & dosagem , Oxifenônio/administração & dosagem , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos RetrospectivosRESUMO
The discussion concerns onset and pathogenesis of functional intestinal diseases. Current data are presented on association of functional intestinal diseases with different infectious agents with illustration on the model of postinfectious irritable colon syndrome (ICS). ICS-like conditions in patients who had previously intestinal infections are considered.
Assuntos
Bactérias/isolamento & purificação , Mucosa Intestinal/microbiologia , Síndrome do Intestino Irritável/microbiologia , Humanos , Fatores de RiscoRESUMO
The aim of the clinical research was to study the efficacy of Saccharomyces boulardii in treatment of patients with Inflammatory Bowel Diseases. Results of investigation demonstrate more rapid regression of intestinal dyspepsia symptoms, decreasing clinical activity of IBD and improvement of intestinal microbiota composition in IBD patients have been treated by Saccharomyces boulardii. Lyophilized Saccharomyces boulardii are compatible with medical agents of the standard IBD therapy and have high level of safety.
Assuntos
Doenças Inflamatórias Intestinais/microbiologia , Doenças Inflamatórias Intestinais/terapia , Saccharomyces , Feminino , Humanos , Intestinos/microbiologia , MasculinoRESUMO
According to the 1996 WHO Report, the world is heading for a major crisis in public health as outbreaks of new and re-emerging infectious diseases are striking at increasing frequencies within the past 10 to 15 years. The given information is true not only for an infection. On the other side eventually a food of the persons considerably changes. The urgent question which needs to be addressed is the nutrition modification and optimization for public health improvement.
Assuntos
Abastecimento de Alimentos , Alimentos , Avaliação Nutricional , Feminino , Humanos , MasculinoRESUMO
Irritable bowel syndrome is one of the most frequent diseases of the digestive system. Psychodiagnostic investigation of patients with IBS testifies to presence of asthenic frustration. In article results of preparation Ladasten use are presented in therapy of patients with irritable bowel syndrome.
Assuntos
Adamantano/análogos & derivados , Ansiedade/tratamento farmacológico , Astenia/tratamento farmacológico , Síndrome do Intestino Irritável/tratamento farmacológico , Adamantano/administração & dosagem , Adamantano/uso terapêutico , Ansiedade/psicologia , Astenia/psicologia , Quimioterapia Combinada , Feminino , Fármacos Gastrointestinais/administração & dosagem , Fármacos Gastrointestinais/uso terapêutico , Humanos , Síndrome do Intestino Irritável/psicologia , Masculino , Testes Neuropsicológicos , Inquéritos e Questionários , Resultado do TratamentoRESUMO
The authors consider mechanism of biliary dysfunction in cholelithiasis responsible for the development of secondary changes in parenchyma and pancreatic ductal system and effect of cholecystectomy on bile lithogenecity in patients with chronic biliary pancreatitis. A high-precision technique for instrumental diagnosis (endosonography) yielded data on the role of microliths and biliary sludge in pathogenesis of chronic biliary pancreatitis. The necessity to use ursodeoxycholic acid derivatives for the treatment of this pathology is substantiated.
Assuntos
Bile/metabolismo , Colecistectomia/efeitos adversos , Colelitíase/cirurgia , Pâncreas/patologia , Pancreatite Crônica/etiologia , Adulto , Idoso , Colagogos e Coleréticos/uso terapêutico , Colangiopancreatografia Retrógrada Endoscópica , Colelitíase/diagnóstico , Endossonografia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Pâncreas/diagnóstico por imagem , Pancreatite Crônica/diagnóstico , Pancreatite Crônica/tratamento farmacológico , Prognóstico , Ácido Ursodesoxicólico/uso terapêuticoRESUMO
AIM: To study efficacy of a combination of proton pump inhibitor (PPI) and bismuth tripotassium dicitrate (BTD) in gastric ulcers (GU) induced by non-steroid anti-inflammatory drugs (NSAD) in rheumatic patients with factors affecting PPI efficacy. MATERIAL AND METHODS: Fifty rheumatic patients entered the study (5 males and 45 females, mean age 63.5 +/- 6.2 years) with NSAD-induced GU. Criteria of participation in the study: ulcer size > 1.0 cm, 2 and more ulcers, administration of glucocorticoids (GC) and/or cytotoxic drugs. The patients were divided into two groups. Group 1 patients received omeprasol 20 mg twice a day + BTD 240 mg twice a day; group 2 patients received omeprasol alone 20 mg twice a day. The groups were matched by demographic and clinical parameters, consisted mainly of women with rheumatoid arthritis, most of the patients took GC, methotrexate or leflunamid. The result of the treatment was evaluated by the findings of endoscopic examination 4 and 8 weeks after treatment. RESULTS: Three patients from group 1 and 2 patients from group 2 were withdrawn from the study. For 4 weeks ulcer heeling was achieved in 15 patients of group 1 (68.2%) and 8 patients of group 2 (34.8%), p = 0.038. On week 8 ulcers healed in 86.3 and 78.3% patients, respectively. Severe side effects were absent. CONCLUSION: Combination of omeprasol with BTD stimulated heeling of NSAD-induced gastric ulcer.
Assuntos
Anti-Inflamatórios não Esteroides/efeitos adversos , Antiulcerosos/uso terapêutico , Omeprazol/uso terapêutico , Compostos Organometálicos/uso terapêutico , Inibidores da Bomba de Prótons/uso terapêutico , Úlcera Gástrica/tratamento farmacológico , Idoso , Anti-Inflamatórios não Esteroides/uso terapêutico , Quimioterapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Úlcera Gástrica/induzido quimicamente , Resultado do TratamentoRESUMO
The article contains information about severe side effects of long-term acid suppression with non-select proton pump inhibitors (PPI) treatment of gastroesophageal reflux disease (GERD). As far as concern patients with heartborn without esophagitis (non-erosive GERD) using PPI doesn't correspond the pathogenesis and hardly has any advantages. Therapy with gastric acidity inhibitors increases risk of acute gastroenteritis and community-acquired pneumonia. Quality of life is rising and symptoms of gastro-esophageal reflux are getting away thanks to topical harmless treatment GERD without severe esophagitis Pepsan-R.
Assuntos
Refluxo Gastroesofágico/tratamento farmacológico , Fármacos Gastrointestinais/uso terapêutico , Antagonistas dos Receptores H2 da Histamina/uso terapêutico , Inibidores da Bomba de Prótons/efeitos adversos , Relação Dose-Resposta a Droga , Fraturas do Colo Femoral/epidemiologia , Fraturas do Colo Femoral/etiologia , Ácido Gástrico/metabolismo , Refluxo Gastroesofágico/etiologia , Refluxo Gastroesofágico/metabolismo , Fármacos Gastrointestinais/administração & dosagem , Fármacos Gastrointestinais/efeitos adversos , Antagonistas dos Receptores H2 da Histamina/administração & dosagem , Antagonistas dos Receptores H2 da Histamina/efeitos adversos , Humanos , Pneumonia/epidemiologia , Pneumonia/etiologia , Inibidores da Bomba de Prótons/administração & dosagem , Inibidores da Bomba de Prótons/uso terapêutico , Qualidade de Vida , Fatores de TempoRESUMO
In this article the comparative analysis of various methods of Helicobacter pylori verification is shown. Also algorithm of optimization of helicobacteriosis diagnostic, developed on the basis of a comparative estimation of results of various diagnostic techniques is presented. According to this algorithm, for increase of accuracy of helicobacteriosis diagnostic it is recommended to use at least two, and it is better three diagnostic methods: the combination of fast urease test or Helic-test with a histologic method (biopsy material from a stomach corpus) or polymerase chain reaction (ureC gene detection) is preferable. For an efficiency estimation of eradication therapy we recommend "Helic-test" as an effective noninvasive method that is especially important for children.
Assuntos
Doenças do Sistema Digestório/microbiologia , Infecções por Helicobacter/microbiologia , Helicobacter pylori/genética , Helicobacter pylori/patogenicidade , Fatores de Virulência/genética , Doenças do Sistema Digestório/tratamento farmacológico , Farmacorresistência Bacteriana/genética , Genes Bacterianos , Infecções por Helicobacter/tratamento farmacológico , Helicobacter pylori/efeitos dos fármacos , Humanos , VirulênciaRESUMO
It is known, that anxiety is one of the most wide-spread mental disorders in-between psychiatric state and it takes part in pathogenesis a lot of somatic diseases as well. At the same time the host bowel microbiota participates in metabolic control of vital human functions such as mood and behavioural reactions. This title connection reveals some new therapeutic opportunity in treatment of psychiatric disorders that based on using with probiotics. In case non-clinically significant anxiety it is claimed to use probiotic (Enterol) however in case clinically significant anxiety it is claimed to use non-benzodiazepine tranquilizer (Stresam).
Assuntos
Ansiolíticos/uso terapêutico , Transtornos de Ansiedade , Enteropatias , Oxazinas/uso terapêutico , Probióticos/uso terapêutico , Transtornos de Ansiedade/complicações , Transtornos de Ansiedade/tratamento farmacológico , Transtornos de Ansiedade/patologia , Transtornos de Ansiedade/fisiopatologia , Comportamento/efeitos dos fármacos , Humanos , Enteropatias/complicações , Enteropatias/dietoterapia , Enteropatias/patologia , Enteropatias/fisiopatologiaAssuntos
Antibacterianos/administração & dosagem , Claritromicina/administração & dosagem , Farmacorresistência Bacteriana , Infecções por Helicobacter , Helicobacter pylori , Úlcera Gástrica , Feminino , Infecções por Helicobacter/tratamento farmacológico , Infecções por Helicobacter/epidemiologia , Humanos , Masculino , Federação Russa/epidemiologia , Úlcera Gástrica/tratamento farmacológico , Úlcera Gástrica/epidemiologia , Úlcera Gástrica/microbiologia , População UrbanaRESUMO
In the article the questions of eating attitudes of people in advanced age are considered. Inspection of 54 people of St. Petersburg in the age from 65 to 84 included questioning (biological, social and questions of eating contents), estimation of eating attitude (the eating attitude test EAT-26, the Dutch eating behaviour questionnaire) and psychological testing (techniques of an estimation of complaints, attitudes, levels of anxiousness, depression, astenia, aggression and quality of life). Symptoms of eating disorders with restrictive and emotional tendencies were registered in 14,8% of people of advanced age. Communications of eating attitude with social factors, eating preferences, application of a diet, a degree of a dissatisfaction of body weight, arterial blood pressure and psychological parameters have been revealed.