[Characteristics of formation of endogenous intoxication syndrome in patients with non-viral chronic hepatitis].

The complex evaluation of the intensity of lipid peroxidation, endogenous intoxication syndrome, blood microcirculation disorder and surfactant activity of blood serum has been performed in patients with hepatitis of non-viral etiology. The article presents the peculiarities of changes of blood medium-molecular peptides, average corpuscular volume of erythrocytes, albumin/gamma-globulin coefficient in patients with chronic hepatitis of non-viral etiology with different activity degree. These indices were proposed to evaluate endogenous intoxication syndrome. On the basis of the analysis of changes of tension-rheometric indices the method of assessment of chronic hepatitis activity of non-viral etiology has been worked out.