RESUMO
AIM: To evaluate the diagnostic utility of long-term remote monitoring of ECG compared with 24 hour Holter monitoring for the detection of cardiac arrhythmias and conduction disturbance in patients with atrial fibrillation (AF) after catheter radiofrequency ablation (RFA; isolation) of the pulmonary veins. MATERIALS AND METHODS: The study included 62 patients aged 58.5±11.1 years, with paroxysmal or persistent AF, after catheter RFA (pulmonary veins isolation). Patients underwent long-term remote ECG monitoring, 24 hour Holter monitoring and transthoracic echocardiogram. RESULTS: After 24 hour Holter monitoring of 62 patients with AF after RFA in 21 of them (33.9%) was detected early recurrence of AF. Remote ECG monitoring of 18 patients, detected AF in 7 patients (39%), 2 of them were asymptomatic AF recurrence. 24 hour Holter monitoring of the same 18 patients AF recurrence was not detected at all (0%). CONCLUSION: Both of devices, long-term remote monitoring of ECG and 24 hour Holter monitoring detected 45.2% of recurrence of AF. Over the wearing of both devises 24 hour Holter and long-term remote monitor the last detected more events among 18 patients (33% vs 0%). Two evens of AF recurrence were asymptomatic.
Assuntos
Fibrilação Atrial , Ablação por Cateter , Eletrocardiografia Ambulatorial , Idoso , Fibrilação Atrial/diagnóstico , Fibrilação Atrial/terapia , Humanos , Pessoa de Meia-Idade , Ablação por Radiofrequência , Recidiva , Fatores de Tempo , Resultado do TratamentoRESUMO
The purpose of this study was to define a correlation between N-terminal proBNP level and extent of cardiac abnormalities. A total of 40 patients with hypertension were included in the study (60.5+/-7.6 years of age; 18 men, 22 women). It was found that patients with hypertension had increased plasma N-terminal proBNP level, that it increased with age and tended to be higher in patients with concentric hypertrophy compared with those with normal geometry and eccentric hypertrophy; however, the differences were not significant. N-terminal proBNP concentration depended on ventricular septal thickness and left ventricular wall thickness. Analysis of association between N-proBNP level and parameters of myocardial diastolic function showed that increased plasma peptide levels correlated with degree of diastolic dysfunction in patients with altered left ventricular relaxation.
Assuntos
Hipertensão/diagnóstico , Hipertensão/fisiopatologia , Peptídeo Natriurético Encefálico/sangue , Fragmentos de Peptídeos/sangue , Idoso , Feminino , Coração/anatomia & histologia , Coração/fisiologia , Coração/fisiopatologia , Testes de Função Cardíaca , Ventrículos do Coração/fisiopatologia , Humanos , Hipertensão/sangue , Hipertensão/patologia , Hipertrofia Ventricular Esquerda , Masculino , Pessoa de Meia-Idade , Remodelação VentricularAssuntos
Bloqueadores dos Canais de Cálcio/uso terapêutico , Hipertensão/tratamento farmacológico , Taquicardia Supraventricular/tratamento farmacológico , Verapamil/uso terapêutico , Pressão Sanguínea/efeitos dos fármacos , Pressão Sanguínea/fisiologia , Frequência Cardíaca/efeitos dos fármacos , Frequência Cardíaca/fisiologia , Humanos , Hipertensão/complicações , Hipertensão/fisiopatologia , Taquicardia Supraventricular/complicações , Taquicardia Supraventricular/fisiopatologia , Resultado do TratamentoRESUMO
The authors review literature data on application of impulsed magnetic field (IMF) in clinical practice. IMF introduction in LE treatment is thought beneficial because IMF antiinflammatory, analgetic effects, positive action on microcirculation, immunological reactivity, the ability to upgrade the effect of combined therapy. The trends observed in the clinical and laboratory indices allowed the authors to recommend IMF for wide application in LE.
Assuntos
Lúpus Eritematoso Sistêmico/terapia , Magnetismo/uso terapêutico , Adolescente , Adulto , Idoso , Criança , Doença Crônica , Quimioterapia Combinada , Estudos de Avaliação como Assunto , Feminino , Humanos , Masculino , Métodos , Pessoa de Meia-Idade , Indução de RemissãoRESUMO
The effects of various procedures and behavior patterns on excessive weight loss are demonstrated in males between 40 and 59 years of age in the course of a program carried out on a standard protocol at 15 sanatoria. The best effect was produced where medical recommendations on diet adjustment were followed strictly, as the reduction of caloric intake was more efficient here, as compared to other diets or exercise. Relative preventive effect was higher, after the same preventive procedures, in individuals with marginal obesity, as compared to those with marked obesity.
Assuntos
Obesidade/prevenção & controle , Adulto , Dieta Redutora , Terapia por Exercício , Hospitais Especializados , Humanos , Masculino , Pessoa de Meia-Idade , Cooperação do PacienteRESUMO
Multifactor prophylaxis of CHD and arterial hypertension was tried in 12 sanatoria in 1982 in the population of men aged 40 to 59 with initial arterial hypertension using a unified method. A significant hypotensive effect was achieved, mainly at the expense of the fact of rest itself under sanatorium conditions as a factor of isolation from stresses of everyday life. A raised level of physical activity played the most important role in preventive measures enhancing this effect.
Assuntos
Doença das Coronárias/prevenção & controle , Hipertensão/terapia , Adulto , Dieta Redutora , Dieta Hipossódica , Estâncias para Tratamento de Saúde , Humanos , Hiperlipidemias/terapia , Hipertensão/prevenção & controle , Masculino , Pessoa de Meia-Idade , Obesidade/dietoterapia , Risco , Prevenção do Hábito de FumarRESUMO
During an outbreak of influenza in April, 1979, caused by A (H1N1) virus the protective effect of remantadine in combination with vaccinations using a national-made live A (H3N2) and inactivated A (H1N1) and B vaccines was studied. The best protective effect was achieved in the subjects vaccinated with influenza vaccines and given remantadine for urgent prophylaxis. Vaccination prophylaxis reduced the incidence of influenza and ARD 1.4-fold, prophylaxis with remantadine alone 2.3-fold.
Assuntos
Adamantano/análogos & derivados , Surtos de Doenças/prevenção & controle , Vacinas contra Influenza/administração & dosagem , Influenza Humana/prevenção & controle , Rimantadina/uso terapêutico , Adolescente , Adulto , Anticorpos Antivirais/análise , Avaliação de Medicamentos , Humanos , Vírus da Influenza A Subtipo H1N1 , Vírus da Influenza A/imunologia , Placebos , Vacinação/métodos , Vacinas Atenuadas/administração & dosagemRESUMO
Under study was the nucleotide content and the level of methylated cytosine (5-MC) in the DNA, isolated from adenocarcinoma of the stomach, gastric mucosa in patients with duodenal ulcer as well as from the mucosa of intact human stomach. The difference (reliable statistically) was found in the amount of 5-MC between the tissues concerned. So, in adenocarcinoma the amount of 5-MC was 4.64 +/- 0.3 mol.%, in gastric mucosa in case of duodenal ulcer--2.63 +/- 0.3 mol.%, while in mucosa of intact stomach--1.52 +/- 0.3 mol.%. The increased level of DNA methylation should influence its structure and activity.
Assuntos
Citosina/análogos & derivados , DNA de Neoplasias/análise , Nucleotídeos/análise , Neoplasias Gástricas/análise , 5-Metilcitosina , Adenocarcinoma/análise , Composição de Bases , Citosina/análise , Úlcera Duodenal/metabolismo , Mucosa Gástrica/análise , Humanos , Masculino , Metilação , Pessoa de Meia-IdadeRESUMO
The protective effect of remantadin during an influenza outbreak in December 1977 caused by A (H1N1) virus was studied. A prophylactic administration of remantadin decreased influenza and ARD incidence by 1.5-fold. A more significant decrease of the incidence (2.5-fold) was observed among the subjects given a combination of remantadin and influenza vaccine (H3N2) a few days before the outbreak, which was apparently due to the interferon-inducing capacity of the vaccine.