Diagnostic utility of long-term remote ECG monitoring in compare with 24 hour Holter monitoring in patients with atrial fibrillation after catheter radiofrequency ablation in the early postoperative period.

AIM: To evaluate the diagnostic utility of long-term remote monitoring of ECG compared with 24 hour Holter monitoring for the detection of cardiac arrhythmias and conduction disturbance in patients with atrial fibrillation (AF) after catheter radiofrequency ablation (RFA; isolation) of the pulmonary veins. MATERIALS AND METHODS: The study included 62 patients aged 58.5±11.1 years, with paroxysmal or persistent AF, after catheter RFA (pulmonary veins isolation). Patients underwent long-term remote ECG monitoring, 24 hour Holter monitoring and transthoracic echocardiogram. RESULTS: After 24 hour Holter monitoring of 62 patients with AF after RFA in 21 of them (33.9%) was detected early recurrence of AF. Remote ECG monitoring of 18 patients, detected AF in 7 patients (39%), 2 of them were asymptomatic AF recurrence. 24 hour Holter monitoring of the same 18 patients AF recurrence was not detected at all (0%). CONCLUSION: Both of devices, long-term remote monitoring of ECG and 24 hour Holter monitoring detected 45.2% of recurrence of AF. Over the wearing of both devises 24 hour Holter and long-term remote monitor the last detected more events among 18 patients (33% vs 0%). Two evens of AF recurrence were asymptomatic.

[N-terminal pro-brain natriuretic peptide and cardiac involvement in patients with hypertensive disease].

The purpose of this study was to define a correlation between N-terminal proBNP level and extent of cardiac abnormalities. A total of 40 patients with hypertension were included in the study (60.5+/-7.6 years of age; 18 men, 22 women). It was found that patients with hypertension had increased plasma N-terminal proBNP level, that it increased with age and tended to be higher in patients with concentric hypertrophy compared with those with normal geometry and eccentric hypertrophy; however, the differences were not significant. N-terminal proBNP concentration depended on ventricular septal thickness and left ventricular wall thickness. Analysis of association between N-proBNP level and parameters of myocardial diastolic function showed that increased plasma peptide levels correlated with degree of diastolic dysfunction in patients with altered left ventricular relaxation.

[The use of a pulsed magnetic field in the treatment of lupus erythematosus]. / Primenenie impul'snogo magnitnogo polia pri lechenii krasnoi volchanki.

The authors review literature data on application of impulsed magnetic field (IMF) in clinical practice. IMF introduction in LE treatment is thought beneficial because IMF antiinflammatory, analgetic effects, positive action on microcirculation, immunological reactivity, the ability to upgrade the effect of combined therapy. The trends observed in the clinical and laboratory indices allowed the authors to recommend IMF for wide application in LE.

[Effect of multifactorial sanatorium-based preventive measures on excessive body weight]. / Vozdeistvie meropriiatii mnogofaktornoi sanatornoi profilaktiki na izbytochnuiu massu tela.

The effects of various procedures and behavior patterns on excessive weight loss are demonstrated in males between 40 and 59 years of age in the course of a program carried out on a standard protocol at 15 sanatoria. The best effect was produced where medical recommendations on diet adjustment were followed strictly, as the reduction of caloric intake was more efficient here, as compared to other diets or exercise. Relative preventive effect was higher, after the same preventive procedures, in individuals with marginal obesity, as compared to those with marked obesity.

[Multi-factor prevention in sanatoria: its effect on increased arterial pressure]. / Mnogofaktornaia profilaktika v sanatoriiakh: vliianie na povyshennoe AD.

Multifactor prophylaxis of CHD and arterial hypertension was tried in 12 sanatoria in 1982 in the population of men aged 40 to 59 with initial arterial hypertension using a unified method. A significant hypotensive effect was achieved, mainly at the expense of the fact of rest itself under sanatorium conditions as a factor of isolation from stresses of everyday life. A raised level of physical activity played the most important role in preventive measures enhancing this effect.

[Study results of the comprehensive influenza prevention with vaccines and remantadine during the influenza A(H1N1) outbreak in 1979]. / Rezul'taty izucheniia kompleksnoi profilaktiki grippa vaktsinami i remantadinom vo vremia vspyshki grippa A(H1N1) v 1979 g.

During an outbreak of influenza in April, 1979, caused by A (H1N1) virus the protective effect of remantadine in combination with vaccinations using a national-made live A (H3N2) and inactivated A (H1N1) and B vaccines was studied. The best protective effect was achieved in the subjects vaccinated with influenza vaccines and given remantadine for urgent prophylaxis. Vaccination prophylaxis reduced the incidence of influenza and ARD 1.4-fold, prophylaxis with remantadine alone 2.3-fold.

[Nucleotide composition and the methylated cytosine level in the DNA from a cancerous stomach tumor]. / Nukleotidnyi sostav i uroven' metilirovannogo tsitolizina v DNK iz rakovoi opukholi zheludka.

Under study was the nucleotide content and the level of methylated cytosine (5-MC) in the DNA, isolated from adenocarcinoma of the stomach, gastric mucosa in patients with duodenal ulcer as well as from the mucosa of intact human stomach. The difference (reliable statistically) was found in the amount of 5-MC between the tissues concerned. So, in adenocarcinoma the amount of 5-MC was 4.64 +/- 0.3 mol.%, in gastric mucosa in case of duodenal ulcer--2.63 +/- 0.3 mol.%, while in mucosa of intact stomach--1.52 +/- 0.3 mol.%. The increased level of DNA methylation should influence its structure and activity.

[Protective action of remantadine during an influenza outbreak caused by virus A (H1N1) in December 1977]. / Izuchenie zashchitnogo deistviia remantadina vo vremia vspyshki grippa, vyzvannoi virusom A (H1N1), v dekabre 1977 g.

The protective effect of remantadin during an influenza outbreak in December 1977 caused by A (H1N1) virus was studied. A prophylactic administration of remantadin decreased influenza and ARD incidence by 1.5-fold. A more significant decrease of the incidence (2.5-fold) was observed among the subjects given a combination of remantadin and influenza vaccine (H3N2) a few days before the outbreak, which was apparently due to the interferon-inducing capacity of the vaccine.