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3.
J Reprod Med ; 51(5): 399-404, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16779987

RESUMO

OBJECTIVE: To assess the feasibility of applying postoperative objective criteria for preoperative evaluation of scheduled gynecologic cases. STUDY DESIGN: A preoperative evaluation program was introduced in which all surgeons were asked to voluntarily submit a 1-page case summary questionnaire for each elective gynecologic surgical procedure. A committee of departmental peers reviewed each submission for appropriateness of indications and completeness of preoperative evaluation. Cases were evaluated against quality assessment criteria sets created by the American College of Obstetricians and Gynecologists. Reviewed summaries were categorized as either meeting criteria, not meeting criteria but appropriate, not meeting criteria or no pertinent criteria available for the procedure planned. RESULTS: In all, 2,005 elective gynecologic surgical procedures were performed by 70 active surgeons during the 1-year study period; 1,166 procedures (58%) were reported. Of 70 surgeons, 57 reported at least 1 procedure, but only 6 were 100% compliant with their surgical submissions. In total, 1,008 procedures (86% of reported cases) met the criteria or were deemed appropriate by committee review. In 166 instances, additional information was requested from and provided by the surgeon before the case could be adjudicated. CONCLUSION: A voluntary program of preoperative surgical case review for scheduled gynecologic procedures appeared feasible but resulted in only modest initial participation.


Assuntos
Procedimentos Cirúrgicos em Ginecologia , Revisão dos Cuidados de Saúde por Pares , Cuidados Pré-Operatórios/métodos , Centros Médicos Acadêmicos , Relações Comunidade-Instituição , Estudos de Viabilidade , Feminino , Guias como Assunto , Procedimentos Cirúrgicos em Ginecologia/métodos , Humanos , Controle de Qualidade
4.
Am J Med Genet A ; 131(2): 179-85, 2004 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-15523614

RESUMO

Ring chromosome 7 is a rare but well documented chromosomal aberration in man. So far at least 14 cases have been reported in the literature showing a variable but distinct pattern of phenotypic characteristics in affected individuals. Besides others, skin findings as pigmented naevi are especially frequent. Loss of chromosomal material from the terminal chromosome arms in the structurally abnormal ring chromosome 7 as well as somatic mosaicism with loss or gain of chromosome 7 has been suggested to be responsible for the clinical symptoms. We now report another case of a ring chromosome 7 in a 14-year-old boy with multiple remarkable congenital naevi, where we could demonstrate for the first time somatic mosaicism showing significant gain of chromosome 7 within a highly proliferating melanocytic congenital naevus (MCN).


Assuntos
Cromossomos Humanos Par 7 , Nevo Pigmentado/congênito , Nevo Pigmentado/genética , Cromossomos em Anel , Anormalidades Múltiplas/genética , Adolescente , Análise Citogenética , Humanos , Hibridização in Situ Fluorescente , Linfócitos , Masculino , Mosaicismo
5.
Melanoma Res ; 14(4): 269-76, 2004 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-15305157

RESUMO

The purpose of the study was to evaluate whether signal-enhanced color Doppler sonography (CDS) is superior to native CDS in detection of characteristic vascularity patterns that are important for the differentiation between benign and malignant lymphadenopathy in patients with cutaneous melanomas. Twenty-two melanoma patients presenting with 24 structures suspicious for metastases in B-Mode sonography were examined using native and signal-enhanced CDS in a prospective two-center study. Presumptive sonographic diagnoses were compared with results of histopathological and follow-up examinations. Signal-enhanced CDS gave additional information about vascularization of lymph node metastases and reactive lymph nodes, which was indicative for the differential diagnosis in 12 of 24 examinations. For lymph node metastases, signal enhancement improved the visualization of accessory peripheral vessels in four of 10 examinations. Concerning reactive lymph nodes, hilar vessels in part with branching to the lymph node periphery could be better identified after application of the contrast enhancer in eight of 13 examinations. Signal-enhanced CDS is demonstrated as an important additional diagnostic tool for improved differentiation between malignant and reactive lymph nodes and may be of special value in preventing unnecessary lymphadenectomy in small reactive lymph nodes.


Assuntos
Metástase Linfática/diagnóstico por imagem , Melanoma/diagnóstico por imagem , Melanoma/patologia , Neoplasias Cutâneas/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Fibroadenoma/diagnóstico por imagem , Fibroadenoma/patologia , Seguimentos , Humanos , Inflamação/diagnóstico por imagem , Inflamação/patologia , Metástase Linfática/patologia , Masculino , Melanoma/irrigação sanguínea , Pessoa de Meia-Idade , Neoplasias Cutâneas/irrigação sanguínea , Neoplasias Cutâneas/diagnóstico por imagem , Ultrassonografia Doppler em Cores
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