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1.
Zhonghua Nan Ke Xue ; 30(2): 132-138, 2024 Feb.
Artigo em Chinês | MEDLINE | ID: mdl-39177346

RESUMO

OBJECTIVE: To investigate the effects of visualized precision electrophysiological diagnosis and transcutaneous low-frequency electrical stimulation (TES) on hypoxia-induced ED in high-altitude areas. METHODS: This study included 152 ED patients from high-altitude hypoxic areas treated by TES based on the parameters obtained from visualized precision electrophysiological diagnosis. We followed up the patients for 1 to 3 months and compared their IIEF-5 scores, nocturnal penile tumescence and rigidity (NPTR) and infrared thermal metabolic technology (TMT)-based temperature of the whole body and diseased parts before and after treatment. RESULTS: All the patients successfully completed 1 to 3 courses of TES. There were no statistically significant differences in the IIEF-5 scores (P<0.05) and penile tip optimal erection rigidity and duration (P<0.01) of the patients before and after treatment. TMT images indicated a temperature change of >1.5 ℃ in the penis and bilateral inguinal regions after treatment, suggesting the effectiveness of electrical stimulation. No recurrence was observed during the follow-up. CONCLUSION: TES based on the parameters obtained from visualized precision electrophysiological diagnosis has a definite effect on hypoxia-induced ED by enhancing oxygen supply to the penile corpus cavernosum and improving its function and structure.


Assuntos
Altitude , Disfunção Erétil , Hipóxia , Estimulação Elétrica Nervosa Transcutânea , Humanos , Masculino , Estimulação Elétrica Nervosa Transcutânea/métodos , Disfunção Erétil/terapia , Disfunção Erétil/diagnóstico , Pênis/fisiopatologia , Ereção Peniana , Resultado do Tratamento
2.
BMC Genomics ; 25(1): 354, 2024 Apr 09.
Artigo em Inglês | MEDLINE | ID: mdl-38594645

RESUMO

The homeodomain-leucine zipper (HD-Zip) gene family plays a pivotal role in plant development and stress responses. Nevertheless, a comprehensive characterization of the HD-Zip gene family in kiwifruit has been lacking. In this study, we have systematically identified 70 HD-Zip genes in the Actinidia chinensis (Ac) genome and 55 in the Actinidia eriantha (Ae) genome. These genes have been categorized into four subfamilies (HD-Zip I, II, III, and IV) through rigorous phylogenetic analysis. Analysis of synteny patterns and selection pressures has provided insights into how whole-genome duplication (WGD) or segmental may have contributed to the divergence in gene numbers between these two kiwifruit species, with duplicated gene pairs undergoing purifying selection. Furthermore, our study has unveiled tissue-specific expression patterns among kiwifruit HD-Zip genes, with some genes identified as key regulators of kiwifruit responses to bacterial canker disease and postharvest processes. These findings not only offer valuable insights into the evolutionary and functional characteristics of kiwifruit HD-Zips but also shed light on their potential roles in plant growth and development.


Assuntos
Actinidia , Proteínas de Homeodomínio , Proteínas de Homeodomínio/genética , Genoma de Planta , Filogenia , Actinidia/genética , Zíper de Leucina/genética , Regulação da Expressão Gênica de Plantas , Proteínas de Plantas/genética , Perfilação da Expressão Gênica
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