Monovalent vaccination with inactivated SARS-CoV-2 BA.5 protects hamsters against Omicron but not non-Omicron variants.

We compared the protective effects of inactivated SARS-CoV-2 vaccines derived from the ancestral and the currently circulating BA.5.2 strains against infection with multiple variants in Syrian golden hamsters. Vaccination with BA.5.2 effectively protected against infection with the Omicron subvariants including XBB.1, but not the Alpha or Delta variant. In contrast, hamsters vaccinated with the ancestral strain demonstrated decent neutralization activity against both the Omicron and non-Omicron variants. Our findings might instruct future design and formulation of SARS-CoV-2 vaccines.

FarSeg++: Foreground-Aware Relation Network for Geospatial Object Segmentation in High Spatial Resolution Remote Sensing Imagery.

Geospatial object segmentation, a fundamental Earth vision task, always suffers from scale variation, the larger intra-class variance of background, and foreground-background imbalance in high spatial resolution (HSR) remote sensing imagery. Generic semantic segmentation methods mainly focus on the scale variation in natural scenarios. However, the other two problems are insufficiently considered in large area Earth observation scenarios. In this paper, we propose a foreground-aware relation network (FarSeg++) from the perspectives of relation-based, optimization-based, and objectness-based foreground modeling, alleviating the above two problems. From the perspective of the relations, the foreground-scene relation module improves the discrimination of the foreground features via the foreground-correlated contexts associated with the object-scene relation. From the perspective of optimization, foreground-aware optimization is proposed to focus on foreground examples and hard examples of the background during training to achieve a balanced optimization. Besides, from the perspective of objectness, a foreground-aware decoder is proposed to improve the objectness representation, alleviating the objectness prediction problem that is the main bottleneck revealed by an empirical upper bound analysis. We also introduce a new large-scale high-resolution urban vehicle segmentation dataset to verify the effectiveness of the proposed method and push the development of objectness prediction further forward. The experimental results suggest that FarSeg++ is superior to the state-of-the-art generic semantic segmentation methods and can achieve a better trade-off between speed and accuracy.

E2SCNet: Efficient Multiobjective Evolutionary Automatic Search for Remote Sensing Image Scene Classification Network Architecture.

Remote sensing image scene classification methods based on deep learning have been widely studied and discussed. However, most of the network architectures are directly reliant on natural image processing methods and are fixed. A few studies have focused on automatic search mechanisms, but they cannot weigh the interpretation accuracy and the parameter quantity for practical application. As a result, automatic global search methods based on multiobjective evolutionary computation have more advantages. However, in the ranking process, the network individuals with large parameter quantities are easy to eliminate, but a higher accuracy may be obtained after full training. In addition, evolutionary neural architecture search methods often take several days. In this article, in order to solve the above concerns, we propose an efficient multiobjective evolutionary automatic search framework for remote sensing image scene classification deep learning network architectures (E2SCNet). In E2SCNet, eight kinds of lightweight operators are used to build a diversified search space, and the coding connection mode is flexible. In the search process, a large model retention mechanism is implemented through two-step multiobjective modeling and evolutionary search, where one step involves the "parameter quantity and accuracy", and the other step involves the "parameter quantity and accuracy growth quantity." Moreover, a super network is constructed to share the weight in the process of individual network evaluation and promote the search speed. The effectiveness of E2SCNet is proven by comparison with several networks designed by human experts and networks obtained by gradient and evolutionary computing-based search methods.

Impact of delayed response on wearable cognitive assistance.

Wearable cognitive assistants (WCA) are anticipated to become a widely-used application class, in conjunction with emerging network infrastructures like 5G that incorporate edge computing capabilities. While prototypical studies of such applications exist today, the relationship between infrastructure service provisioning and its implication for WCA usability is largely unexplored despite the relevance that these applications have for future networks. This paper presents an experimental study assessing how WCA users react to varying end-to-end delays induced by the application pipeline or infrastructure. Participants interacted directly with an instrumented task-guidance WCA as delays were introduced into the system in a controllable fashion. System and task state were tracked in real time, and biometric data from wearable sensors on the participants were recorded. Our results show that periods of extended system delay cause users to correspondingly (and substantially) slow down in their guided task execution, an effect that persists for a time after the system returns to a more responsive state. Furthermore, the slow-down in task execution is correlated with a personality trait, neuroticism, associated with intolerance for time delays. We show that our results implicate impaired cognitive planning, as contrasted with resource depletion or emotional arousal, as the reason for slowed user task executions under system delay. The findings have several implications for the design and operation of WCA applications as well as computational and communication infrastructure, and additionally for the development of performance analysis tools for WCA.