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1.
Nursing ; 54(6): 58-60, 2024 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-38758000

RESUMO

ABSTRACT: Stay interviews can strengthen employee engagement and increase retention. This quality improvement project aimed to determine nurses' motivations for staying on their current unit by conducting peer-led stay interviews. Participants responded positively to the stay interview process.


Assuntos
Entrevistas como Assunto , Motivação , Recursos Humanos de Enfermagem Hospitalar , Grupo Associado , Humanos , Recursos Humanos de Enfermagem Hospitalar/psicologia , Reorganização de Recursos Humanos , Melhoria de Qualidade , Satisfação no Emprego
2.
Part Fibre Toxicol ; 21(1): 14, 2024 Mar 08.
Artigo em Inglês | MEDLINE | ID: mdl-38459567

RESUMO

Wildland fires contribute significantly to the ambient air pollution burden worldwide, causing a range of adverse health effects in exposed populations. The toxicity of woodsmoke, a complex mixture of gases, volatile organic compounds, and particulate matter, is commonly studied in vitro using isolated exposures of conventionally cultured lung cells to either resuspended particulate matter or organic solvent extracts of smoke, leading to incomplete toxicity evaluations. This study aimed to improve our understanding of the effects of woodsmoke inhalation by building an advanced in vitro exposure system that emulates human exposure of the airway epithelium. We report the development and characterization of an innovative system that permits live-cell monitoring of the intracellular redox status of differentiated primary human bronchial epithelial cells cultured at an air-liquid interface (pHBEC-ALI) as they are exposed to unfractionated woodsmoke generated in a tube furnace in real time. pHBEC-ALI exposed to freshly generated woodsmoke showed oxidative changes that were dose-dependent and reversible, and not attributable to carbon monoxide exposure. These findings show the utility of this novel system for studying the molecular initiating events underlying woodsmoke-induced toxicity in a physiologically relevant in vitro model, and its potential to provide biological plausibility for risk assessment and public health measures.


Assuntos
Poluição do Ar , Material Particulado , Humanos , Material Particulado/toxicidade , Fumaça/efeitos adversos , Pulmão , Células Epiteliais
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