Perioperative cardiac complications.

Although infrequent, perioperative cardiac complications are a source of major morbidity and mortality. As the population ages, the prevalence of cardiovascular disease is increasing. For physicians who refer patients for surgery as well as for clinicians directly involved in perioperative medical care, an understanding of perioperative cardiac complications, reduction of such complications, and treatment of complications is essential. This article summarizes the approach to perioperative hypertension, hypotension, myocardial ischemia, myocardial infarction, and congestive heart failure.

Postoperative arrhythmias and conduction disorders.

Cardiac arrhythmias are common in the perioperative period. Most arrhythmias are clinically benign. Occasionally, cardiac arrhythmias and conduction disturbances can pose a major additional risk to the patient in the perioperative and postoperative periods. The current availability of a wide array of techniques for controlling serious arrhythmias--pharmacologic, electrical, and interventional--enable the physician to manage most arrhythmias and conduction disturbances successfully. The added risks posed by arrhythmias and conduction disturbances in the perioperative period now can be minimized.

Use of enoxaparin for the chronically anticoagulated patient before and after procedures.

Patients who require chronic anticoagulation and a procedure have been traditionally managed either by stopping warfarin and starting intravenous standard heparin or by adjusted dose subcutaneous standard heparin or taken off all anticoagulation for a week before the procedure. Enoxaparin may be useful as an alternative method of anticoagulation, avoiding hospitalization and the need for frequent monitoring.

Adenosine radionuclide perfusion imaging in the preoperative evaluation of patients undergoing peripheral vascular surgery.

To define the clinical and adenosine test variables that predicted perioperative cardiac events, 122 patients who received adenosine radionuclide perfusion imaging before peripheral vascular surgery were reviewed. Events included pulmonary edema, an ischemic end point of acute myocardial infarction (AMI) or cardiac death. Five patients underwent coronary revascularization before the surgical procedure. Of the 117 remaining patients, 19 had pulmonary edema, 10 had an AMI, and 2 died after peripheral vascular surgery. Most of the patients (78%) were in an intermediate-risk group as indicated by the presence of > or = 1 clinical risk factor as defined by the Eagle criteria. The only predictor of perioperative pulmonary edema was a history of congestive heart failure (33% vs 4%; p = 0.002). No clinical variables predicted AMI or death. The adenosine variables that were univariate predictors of AMI and death were the number of reversible perfusion defects (1.75 +/- 1.84 vs 0.75 +/- 0.90; p = 0.001) and the number of coronary artery distributions with a radionuclide perfusion defect (1.33 +/- 0.64 vs 0.85 +/- 0.67; p = 0.022). The number of reversible perfusion defects was the only multivariate predictor of ischemic events (p = 0.017). The presence of > 1 reversible defect was associated with an increased frequency of ischemic events (68% vs 28%; p = 0.045). The sensitivity and specificity of > 1 reversible defect was 58% and 73%, respectively, with a positive and negative predictive value of 19% and 94%.(ABSTRACT TRUNCATED AT 250 WORDS)

Approach to the patient with palpitations.

Palpitations are a common complaint present in up to 16% of outpatients. They are nonspecific and in only 15% of patients do they correlate with a cardiac arrhythmia. The significance of palpitations is related to the presence or absence of underlying cardiac disease, the clinical setting in which palpitations occur, and the characteristics and severity of symptoms. This article presents a concise approach to the evaluation of the ambulatory patient with palpitations.

Approaching the surgical patient. Role of the medical consultant.

Medical consultants will no longer "clear patients" but will "prepare them" for surgery instead. They will be required to possess the expertise in assessing a patient's risk for surgery, managing perioperative medications, caring for postoperative complications, maintaining appropriate conduct in the role as consultant, and recording accurate documentation of level of service for third party reimbursement.

Cardiac risk stratification prior to vascular surgery.

A cardiac etiology is the cause of death in approximately 40% to 60% of patients who die in the early postoperative period following vascular surgery. A variety of modalities has been proposed to identify the patient at risk before the surgical procedure. This article puts these modalities in perspective and discusses the increased risk of cardiac complication for the vascular surgery patient, identifies the patient at risk, and defines methods to decrease patient risk.

Noncardiac surgery in the elderly patient with cardiovascular disease.

The elderly patient with cardiovascular disease who undergoes noncardiac surgery presents a challenge to the medical-surgical team. A high prevalence of cardiac disease necessitates a preoperative in-depth search for the presence of cardiovascular risk factors and their reversal if possible. Aging is associated with an altered physiologic response to the stress of surgery as well as to anesthetic agents and perioperative medications, requiring that the elderly patient often be treated quite differently than the younger surgical patient. This article provides guidelines for the estimation of the risk of cardiac complication due to noncardiac surgery and discusses the identification and management of acute and chronic cardiovascular problems in the perioperative period.

Deep vein thrombosis: prophylaxis in acute spinal cord injured patients.

The purpose of this prospective, randomized study was to evaluate the efficacy of low-dose heparin, alone or in combination with electric stimulation, in the prevention of deep vein thrombosis (DVT) in C2 to T11 motor complete and incomplete-preserved motor, nonfunctional spinal cord injured patients. The tibialis anterior and gastrocnemius-soleus muscle groups were stimulated bilaterally, using 50 microsecond pulses given at 10Hz with a four-second "on" and an eight-second "off" cycle for 23 hours daily over a 28-day period. Forty-eight patients, less than two weeks after injury, were randomly assigned to saline placebo (n = 17), low-dose heparin (5,000U, subcutaneous every eight hours) (n = 16), and low-dose heparin plus electric stimulation (n = 15). A normal 125-I fibrinogen scan and impedance plethysmography were required for entry into the study. Surveillance for DVT was evaluated by daily 125-I fibrinogen scanning. Venography was performed to confirm a positive impedance plethysmography and/or 125-I fibrinogen scanning tests for two consecutive days and at the completion of the study. The incidence of DVT was 8 of 17 in the placebo group, 8 of 16 in the low-dose heparin group, and 1 of 15 in the electric stimulation plus low-dose heparin group. The use of electric stimulation plus low-dose heparin significantly (p less than 0.05) decreased the incidence of DVT compared to the other treatments.

Dihydroergotamine/heparin in the prevention of deep-vein thrombosis after total hip replacement. A controlled, prospective, randomized multicenter trial.

In a randomized, double-blind, placebo-controlled multicenter trial, the efficacy and safety of dihydroergotamine mesylate/heparin sodium as a prophylactic agent for deep-vein thrombosis were evaluated in 148 patients who were forty years old or more and who underwent total hip replacement. The incidence of venographically proved postoperative deep-vein thrombosis was 52 per cent in the placebo group and 25 per cent in the dihydroergotamine mesylate/heparin sodium group (p = 0.002). Proximal thrombi developed in only 5 per cent and extensive thrombi, in only 10 per cent of the patients who received dihydroergotamine mesylate/heparin sodium. In contrast, proximal thrombi and extensive thrombi developed in 19 and 25 per cent, respectively, of the patients in the placebo group (p less than 0.05). Adverse reactions in the two groups did not differ significantly: in the treatment group they consisted primarily of hematoma at the site of injection (9 per cent), hematoma at the wound (5 per cent), and excessive postoperative bleeding, and in the placebo group there was hematoma at the site of injection (3 per cent). It was concluded that the combination agent dihydroergotamine mesylate/heparin sodium was effective and safe prophylaxis against deep-vein thrombosis for the patients who underwent total hip replacement in this study.

Noncardiac surgery in the patient with heart disease.

Optimal care of the patient with heart disease undergoing noncardiac surgery requires that the members of the surgical team, including anesthesiologist, internist-cardiologist, and surgeon, be familiar with the cardiovascular response to surgery, preoperative cardiac risk stratification, and the unique pathogenesis of cardiac complications that may occur in the perioperative period. Preoperative evaluation and computation of cardiac risk, anesthetic considerations, along with perioperative care of the patient with ischemic heart disease, valvular heart disease, congestive heart failure, arrhythmias and conduction disorders, and hypertension is discussed.

The medical consultant.

This article reviews the historical development of the medical consultant. The major articles that have set the foundation for this art are reviewed. Future directions and a mnemonic for successful consultations are presented.

Injection of household spray insecticide.

During a three-week period, two patients who had attempted suicide by injecting themselves with commercially available household spray insecticides were seen in our emergency department. Both presented with cellulitis at and adjacent to the injection sites, and both were admitted for intravenous antibiotics, warm soaks, and elevation. In both patients abscesses subsequently developed in the areas of cellulitis. It is not clear whether the pathologic processes in these two patients were primarily due to inoculation of microorganisms or to the effects of the insecticide per se.