Recent advances in functionalized ferrite nanoparticles: From fundamentals to magnetic hyperthermia cancer therapy.

Cancers are fatal diseases that lead to most death of human beings, which urgently require effective treatments methods. Hyperthermia therapy employs magnetic nanoparticles (MNPs) as heating medium under external alternating magnetic field. Among various MNPs, ferrite nanoparticles (FNPs) have gained significant attention for hyperthermia therapy due to their exceptional magnetic properties, high stability, favorable biological compatibility, and low toxicity. The utilization of FNPs holds immense potential for enhancing the effectiveness of hyperthermia therapy. The main hurdle for hyperthermia treatment includes optimizing the heat generation capacity of FNPs and controlling the local temperature of tumor region. This review aims to comprehensively evaluate the magnetic hyperthermia treatment (MHT) of FNPs, which is accomplished by elucidating the underlying mechanism of heat generation and identifying influential factors. Based upon fundamental understanding of hyperthermia of FNPs, valuable insights will be provided for developing efficient nanoplatforms with enhanced accuracy and magnetothermal properties. Additionally, we will also survey current research focuses on modulating FNPs' properties, external conditions for MHT, novel technical methods, and recent clinical findings. Finally, current challenges in MHT with FNPs will be discussed while prospecting future directions.

Tunable linear-to-circular terahertz polarization convertor enabled by a plasmonic nanocomposite metasurface.

We proposed and demonstrated a metasurface based terahertz polarizer consisting of an optically responsive nanocomposite and a flexible base body, which fulfilled the function of linear-to-circular polarization conversion in transmission mode. Meanwhile, as the dynamic and stretchable materials enable the active manipulation of conversion points, evident frequency shifts for circular polarization transformation were discovered by applying laser irradiation and tension. Hence the modulation of conversion points covered a broadband with combination of those two external excitations. This THz polarization convertor may find its applications in polarization controls and beam steering, which also provides a low-cost and large-scale manufacturable method to achieve versatile active THz devices.

Splitting phenomenon of ferromagnetic resonance spectra in NiFe films deposited on periodically rippled sapphire substrates.

The splitting phenomenon of ferromagnetic resonance (FMR) spectra of Ni80Fe20 (NiFe) films deposited on periodically rippled sapphire substrates is studied experimentally and with the help of micromagnetic simulation. The analyses show that the splitting of FMR spectra is related to the periodic ripple topography of films. When the applied magnetic field is perpendicular to the ripple direction, the effective field of periodically rippled films becomes inhomogeneous. The splitting of ferromagnetic resonance spectra originates from localized FMR peaks corresponding to different regions with different effective field intensities in the rippled structure. Furthermore, the relative intensity and position between the split mode and the main FMR mode can be changed by designing ripple topography. This work would help understand the splitting phenomenon of FMR spectra for these NiFe films deposited on the periodically rippled sapphire substrates.

Tune the resonance of VO2 joined metamaterial dimers by adjacent cut wires.

Two terahertz metamaterials were joined by a conductivity variable VO2 patch to obtain a metamaterial dimer. By applying voltage or heat to the VO2 patches, active modulation of terahertz wave could be achieved. A cut-wire metamaterial was placed adjacent to the VO2 joined dimer to affect its electromagnetic response. It was found that the cut wire could heavily impact the resonance mode of the VO2 joined dimer, which gives dual resonance dips in transmission spectrum for both insulating and conducting states of VO2 patches. As a result, by tuning the conductivity of VO2, active dual band phase modulation could be achieved with high transmission window by this dimer-cut wire coupling system.

Design of LDMOS Device Modeling Method Based on Neural Network.

The rapid development of power semiconductor devices is helping to realize a low-carbon society and provide a better life for everyone. Power semiconductors not only are used in many large-scale industrial control fields such as power transmission and control in power grids, rail transit traction systems, and defense weapons and equipment, but also play a vital role in daily equipment such as home appliances, medical electronics, and electronic communications; all devices such as power steering in cars, battery chargers, cell phones, and microwave ovens utilize power electronics. This research mainly focuses on the high-voltage LDMOS device model and its implementation. Based on the in-depth study of the structure and physical mechanism of high-voltage LDMOS devices, with the help of BSIM4 core model, which is now very mature and widely used in industry, the drift region of high-voltage LDMOS is mainly modeled, and the drift region of LDMOS is modeled as a variable resistance controlled by voltage. Finally, Verilog-A language and neural network method are used to establish a compact model of LDMOS. The improved model is applied to LDMOS and can better fit the output characteristics with self-heating effect.

Vacancy tuned coupling in terahertz metamaterial arrays.

Metamaterials have shown great potential for modulation on the amplitude, phase and polarization of the terahertz wave. Here vacancies were introduced into the metamaterial arrays to tune the mutual interaction between the constituent resonators, which could heavily affect the electromagnetic response of the whole metamaterial arrays. We show that the introduced vacancies in the metamaterial arrays can effectively affect the resonance mode of the metamaterial arrays. Based upon the vacancy mediated coupling, a silicon-metal hybrid metamaterial arrays were designed to achieve active modulation of propagating terahertz waves.

High-Performance All-Optical Terahertz Modulator Based on Graphene/TiO2/Si Trilayer Heterojunctions.

In this paper, we demonstrate a trilayer hybrid terahertz (THz) modulator made by combining a p-type silicon (p-Si) substrate, TiO2 interlayer, and single-layer graphene. The interface between Si and TiO2 introduced a built-in electric field, which drove the photoelectrons from Si to TiO2, and then the electrons injected into the graphene layer, causing the Fermi level of graphene to shift into a higher conduction band. The conductivity of graphene would increase, resulting in the decrease of transmitted terahertz wave. And the terahertz transmission modulation was realized. We observed a broadband modulation of the terahertz transmission in the frequency range from 0.3 to 1.7 THz and a large modulation depth of 88% with proper optical excitation. The results show that the graphene/TiO2/p-Si hybrid nanostructures exhibit great potential for terahertz broadband applications, such as terahertz imaging and communication.

Reconfigurable nanoscale spin-wave directional coupler using spin-orbit torque.

We present a reconfigurable nanoscale spin-wave directional coupler based on spin-orbit torque (SOT). By micromagnetic simulations, it is demonstrated that the functionality and operating frequency of proposed device can be dynamically switched by inverting the whole or part of the relative magnetic configuration of the dipolar-coupled waveguides using SOT. Utilizing the effect of sudden change in coupling length, the functionality of power divider can be realized. The proposed reconfigurable spin-wave directional coupler opens a way for two-dimensional planar magnonic integrated circuits.

Semiconductor terahertz modulator arrays: the size and edge effect.

A terahertz spatial modulator is the critical component for active terahertz imaging using compressive sensing. Here small silicon pieces were put in arrays on flexible polymer substrate to fabricate semiconductor terahertz spatial modulators. By doing this, the inter-diffusion of photo-generated charge carriers is prevented for better resolution, and flexibility is achieved. Since the size of silicon is comparable to the wavelength of the terahertz wave, and the dielectric properties of the gap are very different from silicon, the optical modulation of each element is very different from the large silicon. In this Letter, the terahertz wave interaction and optical modulation of the small silicon are systematically studied by time domain spectroscopy. Notably, a strong resonance-like absorption peak was observed in a transmittance spectrum for the small silicon due to the size and edge effect. The spatial modulation of the terahertz wave was also compared between the silicon array and the large silicon samples.

Low Temperature-Derived 3D Hexagonal Crystalline Fe3O4 Nanoplates for Water Purification.

Fe3O4 nanoplates were fabricated by an anodic oxidation process and a subsequent water assisted crystallization process at low temperature, which was found to be very efficient and environmentally friendly. The as-prepared Fe3O4 nanoplates have hexagonal outlines with a thickness of about 20 nm. Tremendous grooves were distributed on the entire surfaces of the nanoplates, making the two-dimension nanoplates have a unique 3D morphology. Transmission electron microscopy results confirmed that the single-crystalline nature of the nanoplates was well maintained. Owing to the unique structures and porous morphologies, the as-prepared 3D nanoplates show excellent ability for absorbing solar energy and absorbing organic pollutants, which can be utilized for cleaning up water. Moreover, the Fe3O4 nanoplates show good magnetic properties that enable them to be easily collected and recycled. We believe this study will inspire the application of Fe3O4 nanoplates with 3D structures in energy and environmental areas.

Preparation and Optical Properties of GeBi Films by Using Molecular Beam Epitaxy Method.

Ge-based alloys have drawn great interest as promising materials for their superior visible to infrared photoelectric performances. In this study, we report the preparation and optical properties of germanium-bismuth (Ge1-xBix) thin films by using molecular beam epitaxy (MBE). GeBi thin films belong to the n-type conductivity semiconductors, which have been rarely reported. With the increasing Bi-doping content from 2 to 22.2%, a series of Ge1-xBix thin film samples were obtained and characterized by X-ray diffraction, scanning electron microscopy, and atomic force microscopy. With the increase of Bi content, the mismatch of lattice constants increases, and the GeBi film shifts from direct energy band-gaps to indirect band-gaps. The moderate increase of Bi content reduces optical reflectance and promotes the transmittance of extinction coefficient in infrared wavelengths. The absorption and transmittance of GeBi films in THz band increase with the increase of Bi contents.

Infrared Properties and Terahertz Wave Modulation of Graphene/MnZn Ferrite/p-Si Heterojunctions.

MnZn ferrite thin films were deposited on p-Si substrate and used as the dielectric layer in the graphene field effect transistor for infrared and terahertz device applications. The conditions for MnZn ferrite thin film deposition were optimized before device fabrication. The infrared properties and terahertz wave modulation were studied at different gate voltage. The resistive and magnetic MnZn ferrite thin films are highly transparent for THz wave, which make it possible to magnetically modulate the transmitted THz wave via the large magnetoresistance of graphene monolayer.

Origin of reduced magnetization and domain formation in small magnetite nanoparticles.

The structural, chemical, and magnetic properties of magnetite nanoparticles are compared. Aberration corrected scanning transmission electron microscopy reveals the prevalence of antiphase boundaries in nanoparticles that have significantly reduced magnetization, relative to the bulk. Atomistic magnetic modelling of nanoparticles with and without these defects reveals the origin of the reduced moment. Strong antiferromagnetic interactions across antiphase boundaries support multiple magnetic domains even in particles as small as 12-14 nm.

Manipulate the magnetic anisotropy of nanoparticle assemblies in arrays.

Tuning the magnetic anisotropy of nanoparticle assemblies is critical for their applications such as on-chip magnetic electronic components and electromagnetic wave absorption. In this work, we developed a facile hierarchical self-assembly method to separately control the magnetic shape and magnetocrystalline anistropy of individual nanoparticle assemblies in arrays. Since magnetic nanoparticle assemblies in the array have the same size, shape and alignment, we are able to study the magnetic properties of individual nanoparticle assembly by measuring the whole arrays. The interplay between the two magnetic anisotropies was systematically studied for disk- and bar-shaped nanoparticle assemblies. Maximum magnetic anisotropy was obtained when the easy axis of magnetic nanoparticles was aligned along the long axes of the bar-shaped nanoparticles assemblies.

Effect of Al2O3 Buffer Layers on the Properties of Sputtered VO2 Thin Films.

VO2 thin films were grown on silicon substrates using Al2O3 thin films as the buffer layers. Compared with direct deposition on silicon, VO2 thin films deposited on Al2O3 buffer layers experience a significant improvement in their microstructures and physical properties. By optimizing the growth conditions, the resistance of VO2 thin films can change by four orders of magnitude with a reduced thermal hysteresis of 4 °C at the phase transition temperature. The electrically driven phase transformation was measured in Pt/Si/Al2O3/VO2/Au heterostructures. The introduction of a buffer layer reduces the leakage current and Joule heating during electrically driven phase transitions. The C-V measurement result indicates that the phase transformation of VO2 thin films can be induced by an electrical field.

Magnetic Nanoparticles: Material Engineering and Emerging Applications in Lithography and Biomedicine.

We present an interdisciplinary overview of material engineering and emerging applications of iron oxide nanoparticles. We discuss material engineering of nanoparticles in the broadest sense, emphasizing size and shape control, large-area self-assembly, composite/hybrid structures, and surface engineering. This is followed by a discussion of several non-traditional, emerging applications of iron oxide nanoparticles, including nanoparticle lithography, magnetic particle imaging, magnetic guided drug delivery, and positive contrast agents for magnetic resonance imaging. We conclude with a succinct discussion of the pharmacokinetics pathways of iron oxide nanoparticles in the human body -- an important and required practical consideration for any in vivo biomedical application, followed by a brief outlook of the field.

Magnetic nanoparticle assembly arrays prepared by hierarchical self-assembly on a patterned surface.

Inverted pyramid hole arrays were fabricated by photolithography and used as templates to direct the growth of colloidal nanoparticle assemblies. Cobalt ferrite nanoparticles deposit in the holes to yield high quality pyramid magnetic nanoparticle assembly arrays by carefully controlling the evaporation of the carrier fluid. Magnetic measurements indicate that the pyramid magnetic nanoparticle assembly arrays preferentially magnetize perpendicular to the substrate.

High-speed and broadband terahertz wave modulators based on large-area graphene field-effect transistors.

We present a broadband terahertz wave modulator with improved modulation depth and switch speed by cautiously selecting the gate dielectric materials in a large-area graphene-based field-effect transistor (GFET). An ultrathin Al2O3 film (∼60 nm) is deposited by an atomic-layer-deposition technique as a high-k gate dielectric layer, which reduces the Coulomb impurity scattering and cavity effect, and thus greatly improves the modulation performance. Our modulator has achieved a modulation depth of 22% and modulation speed of 170 kHz in a frequency range from 0.4 to 1.5 THz, which is a large improvement in comparison to its predecessor of SiO2-based GFET.

A generalized diffusion model for growth of nanoparticles synthesized by colloidal methods.

A nanoparticle growth model is developed to predict and guide the syntheses of monodisperse colloidal nanoparticles in the liquid phase. The model, without any a priori assumptions, is based on the Fick's law of diffusion, conservation of mass and the Gibbs-Thomson equation for crystal growth. In the limiting case, this model reduces to the same expression as the currently accepted model that requires the assumption of a diffusion layer around each nanoparticle. The present growth model bridges the two limiting cases of the previous model i.e. complete diffusion controlled and adsorption controlled growth of nanoparticles. Specifically, the results show that a monodispersion of nanoparticles can be obtained both with fast monomer diffusion and with surface reaction under conditions of small diffusivity to surface reaction constant ratio that results is growth 'focusing'. This comprehensive description of nanoparticle growth provides new insights and establishes the required conditions for fabricating monodisperse nanoparticles critical for a wide range of applications.

Ten-nanometer dense hole arrays generated by nanoparticle lithography.

Large area dense hole arrays with a feature size of ~10 nm were generated using self-assembled monolayers of nanoparticles as etch masks. To fabricate the hole arrays, monolayers of nanoparticles were irradiated by electron beam to turn surfactants into amorphous carbon, treated by acid to remove the nanoparticle cores, and then etched by CF(4) to deepen the holes. Evaporated gold films preferentially diffuse into the holes to generate gold nanoparticle arrays. However no obvious diffusion into holes was observed for a sputtered iron platinum film.