RESUMO
BACKGROUND: Secondary hyperparathyroidism (SHPT) is one of the common complications of end-stage renal disease-uremia, and is mainly manifested as parathyroid hyperplasia and abnormal secretion of parathyroid hormone (PTH). OBJECTIVE: To investigate the value and advantages of contrast-enhanced ultrasound (CEUS) in evaluating the survival of autografts after parathyroidectomy + parathyroid autotransplantation. METHODS: In this study, 125 patients with renal failure due to polycystic kidney disease, chronic nephritis, diabetic nephropathy, lupus nephritis, and atherosclerotic nephropathy were enrolled as the participants and each of them had 4 secondary hyperactive parathyroid glands and underwent parathyroid autotransplantation. One parathyroid gland was taken from each patient and equally divided into 4 parts and placed in the subcutaneous fat of one forearm for transplantation. CEUS was performed 14 days after the transplantation to observe the micro blood supply of the graft and assess the survival and secretory function of the transplanted parathyroid. The grafts were divided into the partial survival group and the total survival group based on the enhancement characteristics. The survival of the grafts was determined by comparing the parathyroid hormone level in bilateral elbow cephalic veins 1 month after surgery. RESULTS: Among the 125 patients, 112 had linear or punctate enhancement of 2-4 parathyroid glands 14 days after surgery, and 13 patients had linear or punctate enhancement of 0-1 parathyroid gland. There were statistically significant differences in the perfusion pattern, enhancement uniformity, and parathyroid hormone levels in the cephalic veins at the elbow on both the graft and non-graft sides among all groups (P< 0.05). CONCLUSION: Compared to the detection of the difference in the parathyroid hormone level in the cephalic vein of bilateral elbows 1 month after surgery, CEUS can reflect the parathyroid survival after transplantation more quickly and accurately 2 weeks later, and provide a more rapid and agile non-invasive clinical diagnosis method.
RESUMO
Purpose: Spectators have a significant impact on match performances in soccer, but to what extent crowd support contributes to the technical and physical performances remains unclear. This study aimed to (1) investigate the differences in terms of technical and physical performances with and without spectators; and (2) identify the key factors differentiating between win and loss when playing with and without the presence of an audience. Methods: Our study examined 794 performance records from 397 matches during the 2019-2020 seasons in the Chinese Soccer Super League. The least absolute shrinkage and selection operator (LASSO)-logistic regression was utilized to select significant predictors. Using an independent t-test and the Mann-Whitney non-parametric test explores the difference between matches with and without spectators. Key factors between win and loss were explored using univariate and multivariate logistic regression analyses. Results: Our study found that cross (p < 0.01, ES = -0.24), shots (p < 0.001, ES = -0.25), and shot accuracy (p < 0.05, ES = -0.18) displayed decreasing trends whereas sprint distances (p < 0.05, ES = 0.16) presented an increasing trend without spectators comparing with the crowd support. Moreover, the above three technical variables were the main factors differentiating between wins and losses. Similarly, team and opponent quality remained important potential factors affecting the match outcome. Conclusion: Match outcome or team performance is determined by a myriad of factors, but there are clear differences in technical and physical performances between matches with and without the presence of an audience. Similarly, our study provides a better explanation for the impact of crowd support on match performances whereby coaches can deploy players and adjust match strategies for ultimate success.