Viable mpox virus in the environment of a patient room.

We conducted a prospective environmental surveillance study to investigate the air, surface, dust, and water contamination of a room occupied by a patient infected with mpox virus (MPXV) at various stages of the illness. The patient tested positive for MPXV from a throat swab and skin lesions. Environmental sampling was conducted in a negative pressure room with 12 unidirectional high efficiency particulate air filter (HEPA) air changes per hour and daily cleaning of the surfaces. A total of 179 environmental samples were collected on days 7, 8, 13, and 21 of illness. Among the days of sampling, air, surface, and dust contamination showed the highest contamination rates on day 7 and 8 of illness, with a gradual decline to the lowest contamination level by day 21. Viable MPXV was isolated from surfaces and dust samples and no viable virus was isolated from the air and water samples.

[Molluscicidal effect comparison between TDS and MNSC in field].

OBJECTIVE: To compare the molluscicidal effects between "Luo-wei" (TDS), a plant molluscicide in 4 percent, and metaldehyde and niclosamide (MNSC) in the field. METHODS: A natural ecological environment with Oncomelania hupensis was selected as the test area, the test concentrations of TDS and MNSC were 2.5 g/m3 and 2 ml/m3 respectively by the immersion method; the test doses of TDS and MNSC were 3 g/m2 and 2 ml/m2 respectively by the spray method; the doses of WPN in a control group were 2 g/m3 and 2 g/m2 respectively by the two methods above-mentioned. The molluscicidal effects between TDS and MNSC were compared by using the synchronous design method and parallel comparative method. RESULTS: In the TDS group, the death rate of snails was 90.70% by immersion for 24 hours, reached to 81.40% after spraying for 7 days, and there were no significant differences among the observation time points in molluscicidal effects (P > 0.05). One day after the spraying, the death rate of snails was less in the TDS group compared with that in the MSCN group (P < 0.01), but the death rates of snails were similar in both groups 3 days after the spraying (P > 0.05). In the MSCN group, the death rate of snails was 99.17% by immersion for 24 hours, reached to 66.07% by spraying for 1 day. In the WPS group, the death rate of snails was 97.15% by immersion for 24 hours, reached to 71.43% after spraying for 1 day, and there were no significant differences (both P > 0.05). CONCLUSION: TDS has a good molluscicidal activity and stable efficacy, and the molluscicidal effect of TDS is similar to that of MSCN in the filed, but the molluscicidal sensitivity of TDS is lower than that of MSCN.

[Development of performance evaluation and management system on advanced schistosomiasis medical treatment].

OBJECTIVE: To construct a performance evaluation and management system on advanced schistosomiasis medical treatment, and analyze and evaluate the work of the advanced schistosomiasis medical treatment over the years. METHODS: By applying the database management technique and C++ programming technique, we inputted the information of the advanced schistosomiasis cases into the system, and comprehensively evaluated the work of the advanced schistosomiasis medical treatment through the cost-effect analysis, cost-effectiveness analysis, and cost-benefit analysis. RESULTS: We made a set of software formula about cost-effect analysis, cost-effectiveness analysis, and cost-benefit analysis. This system had many features such as clear building, easy to operate, friendly surface, convenient information input and information search. It could benefit the performance evaluation of the province's advanced schistosomiasis medical treatment work. CONCLUSION: This system can satisfy the current needs of advanced schistosomiasis medical treatment work and can be easy to be widely used.

[Analysis of advanced schistosomiasis situation in Hubei Province, 2004-2011].

There were 39 996 cases of advanced schistosomiasis in Hubei Province, 2004-2011, and most of them were of ascites type. During the period of 8 years, the assistance rate was 97.14%, the cure rate was 14.54%, the mortality rate was 5.59%, and the newly increased rates and the mortality rates declined year by year.