Exploring the relationship between perceived loneliness and subjective cognitive decline in older individuals.

OBJECTIVE: Loneliness has been associated to a greater risk of cognitive decline and dementia in older individuals. However, evidence on whether this association also exists for older individuals who complain of cognitive problems is limited. We conducted a survey to examine the association between subjective cognitive decline in the working memory domain, perceived loneliness, depression, anxiety, and stress in older individuals with different profiles. METHODS: A total of 302 healthy, old individuals completed 3 questionnaires to assess subjective cognitive problems in attention, executive functions, storage, depression, anxiety, stress, and perceived loneliness. RESULTS: We conducted a cluster analysis and 3 clusters of individuals with different profiles emerged. Individuals with greater subjective cognitive problems (cluster 1) in the attention and storage domains, reported higher perceived loneliness and stress but not depression. In contrast, individuals with the least subjective cognitive problems (cluster 3) in the storage domain, reported lower perceived loneliness. CONCLUSIONS: Individuals with higher subjective cognitive decline also report higher levels of perceived loneliness but not more depression than their peers. However, this correlation is present only for individuals with mild subjective cognitive decline (cluster 2). The implications for future research and interventions are discussed.

The relationship between self, value-based reward, and emotion prioritisation effects.

People show systematic biases in perception, memory, attention, and decision-making to prioritise information related to self, reward, and positive emotion. A long-standing set of experimental findings points towards putative common properties of these effects. However, the relationship between them remains largely unknown. Here, we addressed this question by assessing and linking these prioritisation effects generated by a common associative matching procedure in three experiments. Self, reward, and positive emotion prioritisation effects were assessed using cluster and shift function analyses to explore and test associations between these effects across individuals. Cluster analysis revealed two distinct patterns of the relationship between the biases. Individuals with faster responses showed a smaller reward and linear positive association between reward and emotion biases. Individuals with slower responses demonstrated a large reward and no association between reward and emotion biases. No evidence of the relationship between self and value-based reward or positive emotion prioritisation effects was found among the clusters. A shift function indicated a partial dominance of high-reward over low-reward distributions at later processing stages in participants with slower but not faster responses. Full stochastic dominance of self-relevance over others and positive over neutral emotion was pertinent to each subgroup of participants. Our findings suggest the independent origin of the self-prioritisation effect. In contrast, commonalities in cognitive mechanisms supporting value-based reward and positive emotion processing are subject to individual differences. These findings add important evidence to a steadily growing research base about the relationship between basic behavioural drivers.

Social contacts and loneliness affect the own age bias for emotional faces.

Individuals are better at recognizing faces of their own age group (Own Age Bias) but it is unclear whether this bias occurs also for emotional faces and to what extent is affected by loneliness. Young individuals (N = 235) completed an age categorization task on faces of young and old individuals showing neutral, happy, and angry expressions. After a filler task, they categorized as seen or novel the original set of faces intermixed with a new set. Findings showed an Own Age Bias for novel young faces but no evidence that emotion eliminates it. Recognition accuracy was better for emotional faces, but the two factors did not interact. Importantly, low loneliness was linked to an Own Age Bias for novel happy faces. These findings are discussed in the context of current theoretical accounts of the Own Age Bias and of the effects of loneliness on attention and memory.

Perceived Impact of Outdoor Swimming on Health: Web-Based Survey.

BACKGROUND: Outdoor swimming in lakes, lidos (outdoor pools), rivers, and the sea has grown in popularity in many countries, including the United Kingdom. Many anecdotal accounts indicate improvements in medical conditions, which are considered a consequence of outdoor swimming. OBJECTIVE: The aim of this study is to better understand outdoor swimmers' perceptions of their health and the extent to which participation impacted their existing self-reported symptoms. METHODS: A survey was conducted to investigate outdoor swimming behaviors and reports of any diagnosed medical conditions. Medical conditions were coded into categories, and descriptive statistics were generated regarding the outdoor swimmers' behaviors and the effect that outdoor swimming had on their medical symptoms if any. The medical categories were clustered into five larger categories based on their prevalence in the current sample: mental health; musculoskeletal and injury; neurological; cardiovascular and blood disease; and other, which comprises inflammatory, immune, endocrine, and respiratory conditions. RESULTS: In total, 722 outdoor swimmers responded, of whom 498 (68.9%) were female. The probability of outdoor swimming having some positive impact on health across all medical categories was 3.57 times higher compared with no impact (B=1.28, 95% CI 0.63-1.91; P<.001), 44.32 times higher for the mental health category (B=3.79, 95% CI 2.28-5.30; P<.001), 5.25 times higher for musculoskeletal and injury category (B=1.66, 95% CI 0.52-2.79; P=.004), and 4.02 times higher for the other category (B=1.39, 95% CI 0.27-2.51; P=.02). Overall, outdoor swimming was associated with perceived reductions in symptoms of poor mental health (χ22=25.1; P<.001), musculoskeletal and injury (χ22=8.2; P=.04), cardiovascular and blood (χ22=14.7; P=.006), and other conditions (χ22=18.2; P<.001). CONCLUSIONS: Physical activity in the form of outdoor swimming is perceived to have positive impacts on health and is associated with perceived symptom reductions in mental health, musculoskeletal and injury, and cardiovascular and blood conditions. This study cannot provide causal relationships or provide mechanistic insights. However, it does provide a starting point for more targeted prospective intervention research into individual conditions or categories of conditions to establish the impact in those who choose to start outdoor swimming.

Self-prioritization is supported by interactions between large-scale brain networks.

Resting-state functional magnetic resonance imaging (fMRI) has provided solid evidence that the default mode network (DMN) is implicated in self-referential processing. The functional connectivity of the DMN has also been observed in tasks where self-referential processing leads to self-prioritization (SPE) in perception and decision-making. However, we are less certain about whether (i) SPE solely depends on the interplay within parts of the DMN or is driven by multiple brain networks and (ii) whether SPE is associated with a unique component of interconnected networks or can be explained by related effects such as emotion prioritization. We addressed these questions by identifying and comparing topological clusters of networks involved in self-and emotion prioritization effects generated in an associative-matching task. Using network-based statistics, we found that SPE controlled by emotion is supported by a unique component of interacting networks, including the medial prefrontal part of the DMN (MPFC), frontoparietal network (FPN) and insular salience network (SN). This component emerged as a result of a focal effect confined to few connections, indicating that interaction between DMN, FPC and SN is critical to cognitive operations for the SPE. This result was validated on a separate data set. In contrast, prioritization of happy emotion was associated with a component formed by interactions between the rostral prefrontal part of SN, posterior parietal part of FPN and the MPFC, whereas sad emotion reveals a cluster of the DMN, dorsal attention network (DAN) and visual medial network (VMN). We discussed theoretical and methodological aspects of these findings within the more general domain of social cognition.

It is not always positive: emotional bias in young and older adults.

Healthy ageing has been associated with a bias toward positive information and greater psychological well-being. However, to what extent this positivity bias also applies to prioritizing positive information under emotional competition is unclear. Old and young adults performed a word-face interference task, in which they responded to the valence of positive and negative target-words while ignoring happy or angry distractor-faces that could be affectively congruent or incongruent. A control condition with scrambled neutral distractor-faces was also used. Findings showed small facilitation effects with faster responses when targets and distractors were affectively congruent and large interference effects with slower responses when targets and distractors were affectively incongruent compared to the control condition. Importantly, whereas for younger adults there was a similar pattern of interference from happy and angry distractor-faces, for older adults there was greater interference from angry distractor-faces. The present findings are discussed in the context of emotional bias literature.

Self-Positivity or Self-Negativity as a Function of the Medial Prefrontal Cortex.

Self and emotions are key motivational factors of a person strivings for health and well-being. Understanding neural mechanisms supporting the relationship between these factors bear far-reaching implications for mental health disorders. Recent work indicates a substantial overlap between self-relevant and emotion information processing and has proposed the medial prefrontal cortex (MPFC) as one shared neural signature. However, the precise cognitive and neural mechanisms represented by the MPFC in investigations of self- and emotion-related processing are largely unknown. Here we examined whether the neural underpinnings of self-related processing in the MPFC link to positive or negative emotions. We collected fMRI data to test the distinct and shared neural circuits of self- and emotion-related processing while participants performed personal (self, friend, or stranger) and emotion (happy, sad, or neutral) associative matching tasks. By exploiting tight control over the factors that determine the effects of self-relevance and emotions (positive: Happy vs. neutral; negative: Sad vs. neutral), our univariate analysis revealed that the ventral part of the MPFC (vmPFC), which has established involvement in self-prioritisation effects, was not recruited in the negative emotion prioritisation effect. In contrast, there were no differences in brain activity between the effects of positive emotion- and self-prioritisation. These results were replicated by both region of interest (ROI)-based analysis in the vmPFC and the seed- to voxel functional connectivity analysis between the MPFC and the rest of the brain. The results suggest that the prioritisation effects for self and positive emotions are tightly linked together, and the MPFC plays a large role in discriminating between positive and negative emotions in relation to self-relevance.

Illness Perception Mediates the Relationship Between the Severity of Symptoms and Perceived Health Status in Patients With Behçet Disease.

OBJECTIVE: The aim of this study was to investigate the relationship between psychological representations of illness, perceived health status, and self-assessment of symptom severity in patients with Behçet disease, a rare long-term incurable condition with unclear etiology. METHODS: Using cross-sectional survey design, data on self-administered questionnaires on illness perception, health status, symptoms severity, and demographic characteristics were collected from 273 patients with Behçet disease (age range, 18-65 years). The data were subjected to mediation analysis to test whether cognitive and emotional components of illness perception mediate the relationship between the severity of symptoms and heath status. RESULTS: The results support our hypotheses that cognitive components of illness perception (perceived consequences and identity of the illness) mediate the link between symptom activity and pain, whereas emotional components of the illness (emotional representations about the illness) mediate the relationship between disease activity and perceived energy level. CONCLUSIONS: The robustness of these mediation effects suggests potential directions for clinical psychologists and health care practitioners in developing support programs. We supplement our study with Open Access database containing information about type of medication, comorbid mood disorder, and detailed measurement of the severity of BD symptoms for sharing and accumulating multidisciplinary knowledge aiming to support the development of interventions. Addressing psychological aspects of BD will help to manage complex patients effectively.

An anterior-posterior axis within the ventromedial prefrontal cortex separates self and reward.

Although theoretical discourse and experimental studies on the self- and reward-biases have a long tradition, currently we have only a limited understanding of how the biases are represented in the brain and, more importantly, how they relate to each other. We used multi-voxel pattern analysis to test for common representations of self and reward in perceptual matching in healthy human subjects. Voxels across an anterior-posterior axis in ventromedial prefrontal cortex (vmPFC) distinguished (i) self-others and (ii) high-low reward, but cross-generalization between these dimensions decreased from anterior to posterior vmPFC. The vmPFC is characterized by a shift from a common currency for value to independent, distributed representations of self and reward across an anterior-posterior axis. This shift reflected changes in functional connectivity between the posterior part of the vmPFC and the frontal pole when processing self-associated stimuli, and the middle frontal gyrus when processing stimuli associated with high reward. The changes in functional connectivity were correlated with behavioral biases, respectively, to the self and reward. The distinct representations of self and reward in the posterior vmPFC are associated with self- and reward-biases in behavior.

Integration of identity and emotion information in faces: fMRI evidence.

Separate neural systems have been implicated in the recognition of facial identity and emotional expression. A growing number of studies now provide evidence against this modular view by demonstrating that integration of identity and emotion information enhances face processing. Yet, the neural mechanisms that shape this integration remain largely unknown. We hypothesize that the presence of both personal and emotional expression target information triggers changes in functional connectivity between frontal and extrastriate areas in the brain. We report and discuss three important findings. First, the presence of target identity and emotional expression in the same face was associated with super capacity and violations of the independent processing of identity and expression cues. Second, activity in the orbitofrontal cortex (OFC) was associated with the presence of redundant targets and changes in functional connectivity between a particular region of the right OFC (BA11/47) and bilateral visual brain regions (the inferior occipital gyrus (IOG)). Third, these changes in connectivity showed a strong link to behavioural measures of capacity processing. We suggest that the changes in functional connectivity between the right OFC and IOG reduce variability of BOLD responses in the IOG, enhancing integration of identity and emotional expression cues in faces.

Changes in intrinsic functional connectivity and group relevant salience: The case of sport rivalry.

Studies have shown that attending to salient group relevant information could increase the BOLD activity across distributed neural networks. However, it is unclear how attending to group relevant information changes the functional connectivity across these networks. We investigated this issue combining resting states and task-based fMRI experiment. The task involved football fans learning associations between arbitrary geometric shapes and the badges of in-group, the rival and the neutral football teams. Upon learning, participants viewed different badge/shape pairs and their task was to judge whether the viewed pair was a match or a mismatch. For whole brain analyses increased activity was found in the IFG, DLPFC, AI, fusiform gyrus, precuneus and pSTS (all in the left hemisphere) for the rival over the in-group mismatch. Further, the ROI analyses revealed larger beta-values for the rival badge in the left pSTS, left AI and the left IFG. However, larger beta-values were found in the left pSTS and the left IFG (but not AI) for the in-group shape. The intrinsic functional connectivity analyses revealed that compare to the pre-task, post task functional connectivity was decreased between the left DLPFC and the left AI. In contrast, it was increased between the left IFG and the left AI and this was correlated with the difference in RT for the rival vs. in-group team. Our findings suggest that attending to group relevant information differentially affects the strength of functional coupling in attention networks and this can be explained by the saliency of the group relevant information.

Dissociating biases towards the self and positive emotion.

We examined whether self-biases in perceptual matching reflect the positive valence of self-related stimuli. Participants associated geometric shapes with either personal labels (e.g., you, friend, stranger) or faces with different emotional expressions (e.g., happy, neutral, sad). They then judged whether shape-label or shape-face pairs were as originally shown or re-paired. Match times were faster to self-associated stimuli and to stimuli associated with the most positive valence. In addition, both the self-bias and the positive emotion bias were reliable across individuals in different test sessions. In contrast there was no sign of a correlation between the self-bias and the emotion-bias effects. We argue that self-bias and the bias to stimuli linked to positive emotion are separate and may reflect different underlying processes.

Super-capacity me! Super-capacity and violations of race independence for self- but not for reward-associated stimuli.

Participants are biased in responding to stimuli associated with themselves compared with stimuli related to other people. This self-bias may reflect the reward value of self-related stimuli (Sui, He, & Humphreys, 2012). In this article, we examined the identification of self- and reward-associated stimuli under conditions in which either single or redundant stimuli were presented. The redundant stimuli could be the same shape or they could be different shapes both associated with either the self or a friend or high or low reward. We formally tested whether the redundant stimuli violated the independent race model for the identification of multiple stimuli (Miller, 1982) and whether the redundant stimuli were processed with super- or limited-capacity (Townsend & Eidels, 2011). We found that redundant self stimuli alone both violated the independent race model and were processed with super-capacity. In contrast, the redundant high reward stimuli did not show race inequality and were associated with limited capacity processing. The data advance our theoretical understanding of self bias both by demonstrating that it can be distinguished from effects of reward, and by suggesting that self-bias can result from the enhanced integration of stimuli associated with the self. The implications for understanding self bias effects are discussed.

The processing of facial identity and expression is interactive, but dependent on task and experience.

Facial identity and emotional expression are two important sources of information for daily social interaction. However the link between these two aspects of face processing has been the focus of an unresolved debate for the past three decades. Three views have been advocated: (1) separate and parallel processing of identity and emotional expression signals derived from faces; (2) asymmetric processing with the computation of emotion in faces depending on facial identity coding but not vice versa; and (3) integrated processing of facial identity and emotion. We present studies with healthy participants that primarily apply methods from mathematical psychology, formally testing the relations between the processing of facial identity and emotion. Specifically, we focused on the "Garner" paradigm, the composite face effect and the divided attention tasks. We further ask whether the architecture of face-related processes is fixed or flexible and whether (and how) it can be shaped by experience. We conclude that formal methods of testing the relations between processes show that the processing of facial identity and expressions interact, and hence are not fully independent. We further demonstrate that the architecture of the relations depends on experience; where experience leads to higher degree of inter-dependence in the processing of identity and expressions. We propose that this change occurs as integrative processes are more efficient than parallel. Finally, we argue that the dynamic aspects of face processing need to be incorporated into theories in this field.

Interactions between Identity and Emotional Expression in Face Processing across the Lifespan: Evidence from Redundancy Gains.

We tested how aging affects the integration of visual information from faces. Three groups of participants aged 20-30, 40-50, and 60-70 performed a divided attention task in which they had to detect the presence of a target facial identity or a target facial expression. Three target stimuli were used: (1) with the target identity but not the target expression, (2) with the target expression but not the target identity, and (3) with both the target identity and target expression (the redundant target condition). On nontarget trials the faces contained neither the target identity nor expression. All groups were faster in responding to a face containing both the target identity and emotion compared to faces containing either single target. Furthermore the redundancy gains for combined targets exceeded performance limits predicted by the independent processing of facial identity and emotion. These results are held across the age range. The results suggest that there is interactive processing of facial identity and emotion which is independent of the effects of cognitive aging. Older participants demonstrated reliably larger size of the redundancy gains compared to the young group that reflect a greater experience with faces. Alternative explanations are discussed.

Differential interactions between identity and emotional expression in own and other-race faces: effects of familiarity revealed through redundancy gains.

We examined relations between the processing of facial identity and emotion in own- and other-race faces, using a fully crossed design with participants from 3 different ethnicities. The benefits of redundant identity and emotion signals were evaluated and formally tested in relation to models of independent and coactive feature processing and measures of processing capacity for the different types of stimuli. There was evidence for coactive processing of identity and emotion that was linked to super capacity for own-race but not for other-race faces. In addition, the size of the redundancy gain for other-race faces varied with the amount of social contact participants had with individuals from the other race. The data demonstrate qualitative differences in the processing of facial identity and emotion cues in own and other races. The results also demonstrate that the level of integration of identity and emotion cues in faces may be determined by life experience and exposure to individuals of different ethnicities.

Interactions between facial emotion and identity in face processing: evidence based on redundancy gains.

Interactions between the processing of emotion expression and form-based information from faces (facial identity) were investigated using the redundant-target paradigm, in which we specifically tested whether identity and emotional expression are integrated in a superadditive manner (Miller, Cognitive Psychology 14:247-279, 1982). In Experiments 1 and 2, participants performed emotion and face identity judgments on faces with sad or angry emotional expressions. Responses to redundant targets were faster than responses to either single target when a universal emotion was conveyed, and performance violated the predictions from a model assuming independent processing of emotion and face identity. Experiment 4 showed that these effects were not modulated by varying interstimulus and nontarget contingencies, and Experiment 5 demonstrated that the redundancy gains were eliminated when faces were inverted. Taken together, these results suggest that the identification of emotion and facial identity interact in face processing.