1.
Discov Nano
; 18(1): 81, 2023 Jun 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37382753
RESUMO
The development of oligonucleotide nanoassemblies with small molecules has shown great potential in bio-medical applications. However, the interaction of negatively charged oligonucleotides with halogenated small molecules represents a scientific challenge. Here, we introduced a distinct allyl bromide halogenated scaffold, which exhibits specific interaction with adenine nucleic bases of the oligonucleotides, thus leading to the formation of self-assembled nanostructures.