RESUMO
Ginsenosides are the main active component of Panax ginseng. It has been shown that ginsenosides have antineoplastic, antiaging, immunologic function enhancing and other pharmacological actions. In this article, result of experimental studies showed ginsenosides extracted from stem and leaf of Panax ginseng (GSL) has inductive differentiation effect on all types of acute nonlymphocytic leukemia cells in primary culture. The effect on M5, M4 was most potent, followed by M1, M2 and the least, on M3. Through analysis, it was considered that the inductive differentiation effect of ginsenosides might be due to the comprehensive effect of increasing intracellular cAMP and inducing interferon. Since GSL have some other important actions, therefore, if it could be used as a differentiation inducer in clinical practice or combined with other antineoplastic drugs, it would show co-antineoplastic actions in many aspect.
Assuntos
Transformação Celular Neoplásica/efeitos dos fármacos , Leucemia Mieloide Aguda/tratamento farmacológico , Leucemia Mieloide Aguda/patologia , Saponinas/uso terapêutico , Adolescente , Adulto , Idoso , Diferenciação Celular , Feminino , Ginsenosídeos , Humanos , Leucemia Monocítica Aguda/tratamento farmacológico , Leucemia Monocítica Aguda/patologia , Leucemia Mielomonocítica Aguda/tratamento farmacológico , Leucemia Mielomonocítica Aguda/patologia , Masculino , Pessoa de Meia-Idade , Panax , Plantas MedicinaisRESUMO
This article introduces a new method of combining the oral surgery and oral prosthesis into one operation. This method can greatly shorten treatment time. It is used to treat a badly decayed tooth with an apical lesion and to repair it with a post crown at the same time. Since March 1975 more than 20 cases have been treated in this manner with a favorable outcome.